[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100610772":3},{"organization":4,"armGroups":7,"interventions":21,"overallOfficials":37,"centralContacts":43,"locations":53,"responsibleParty":76,"collaborators":27,"id":79,"slug":80,"hasResults":81,"nctId":82,"briefTitle":83,"officialTitle":84,"acronym":85,"eligibilityCriteria":86,"healthyVolunteers":81,"sex":87,"minAge":88,"maxAge":89,"enrollmentInfo":90,"targetDuration":27,"studyType":93,"phases":94,"briefSummary":96,"conditions":97,"keywords":99,"overallStatus":55,"whyStopped":27,"lastUpdateSubmitDate":104,"lastUpdatePostDateStruct":105,"startDateStruct":108,"completionDateStruct":110,"leadSponsor":112,"locationsCount":113},{"fullName":5,"class":6},"Ataturk University","OTHER",[8,16],{"label":9,"type":10,"description":11,"interventionNames":12},"ITM + SAPB + Dex","EXPERIMENTAL","Before induction, 200 µg intrathecal morphine via a 27G Sprotte spinal needle from L3-L4; intraoperative 1 g paracetamol IV and 50 mg dexketoprofen IV; dexmedetomidine 0.5 µg\u002Fkg loading (15 min) followed by a 0.5 µg\u002Fkg\u002Fh infusion; unilateral SAPB with 30 mL of 0.25% bupivacaine under ultrasound guidance at the end of surgery; basal tramadol PCA without infusion IV in the PACU (20 mg each bolus, maximum 200 mg\u002F24 h); if necessary, 50 mg tramadol IV for VAS\\>4.",[13,14,15],"Drug: Intrathecal Morphine","Procedure: Serratus Anterior Plane Block (SAPB) group","Drug: Dexmedetomidine",{"label":17,"type":18,"description":19,"interventionNames":20},"SAPB + Dex (No ITM)","ACTIVE_COMPARATOR","Same protocol, but no intrathecal morphine. Intraoperatively, 1 g paracetamol IV and 50 mg dexketoprofen IV; dexmedetomidine 0.5 µg\u002Fkg loading dose (15 min) followed by a 0.5 µg\u002Fkg\u002Fh infusion; unilateral SAPB with 30 mL of 0.25% bupivacaine at the end of surgery; basal intravenous tramadol PCA (20 mg each bolus, maximum 200 mg\u002F24 h) in the PACU; if necessary, 50 mg tramadol IV for VAS \\>4.",[14,15],[22,28,33],{"type":23,"name":24,"description":25,"armGroupLabels":26,"otherNames":27},"DRUG","Intrathecal Morphine","200 µg morphine sulfate, single-dose via L3-L4, 27G Sprotte spinal needle, prior to induction.",[9],null,{"type":29,"name":30,"description":31,"armGroupLabels":32,"otherNames":27},"PROCEDURE","Serratus Anterior Plane Block (SAPB) group","Ultrasound-guided unilateral SAPB at end of surgery with 30 mL 0.25% bupivacaine.",[9,17],{"type":23,"name":34,"description":35,"armGroupLabels":36,"otherNames":27},"Dexmedetomidine","Loading dose 0.5 µg\u002Fkg over 15 minutes, then 0.5 µg\u002Fkg\u002Fh continuous infusion intraoperatively.",[9,17],[38,41],{"name":39,"affiliation":5,"role":40},"İREM ATEŞ","PRINCIPAL_INVESTIGATOR",{"name":42,"affiliation":5,"role":40},"Nuray Uzun",[44,49],{"name":45,"role":46,"phone":47,"phoneExt":27,"email":48},"İrem Ateş Associate Professor (Doçent Doktor)","CONTACT","+90 532 740 12 58","driremates@hotmail.com",{"name":50,"role":46,"phone":51,"phoneExt":27,"email":52},"Mehmet Akif Yılmaz, assistant doctor","+90 534 653 35 39","mehmetakifyilmaz025@gmail.com",[54,67],{"facility":5,"status":55,"city":56,"state":27,"zip":57,"country":58,"countryCode":27,"cosmosGeoPoint":59,"geoPoint":64,"contacts":65},"RECRUITING","Erzurum","25000","Turkey (Türkiye)",{"type":60,"coordinates":61},"Point",[62,63],41.27694,39.90861,{"lat":63,"lon":62},[66],{"name":50,"role":46,"phone":51,"phoneExt":27,"email":52},{"facility":5,"status":55,"city":56,"state":27,"zip":68,"country":58,"countryCode":27,"cosmosGeoPoint":69,"geoPoint":71,"contacts":72},"25240",{"type":60,"coordinates":70},[62,63],{"lat":63,"lon":62},[73],{"name":74,"role":46,"phone":75,"phoneExt":27,"email":52},"Mehmet Akif Yilmaz","05346533539",{"type":40,"investigatorFullName":77,"investigatorTitle":78,"investigatorAffiliation":5,"oldNameTitle":27,"oldOrganization":27},"irem ateş","Principal Investigator İrem Ateş","100610772","intrathecal-morphine-for-recovery-and-outcomes-after-vats-100610772",false,"NCT07231926","Intrathecal Morphine for Recovery and Outcomes After VATS","The Effects of Intrathecal Morphine in Addition to Serratus Anterior Plane Block and Dexmedetomidine on Postoperative Recovery (QoR-15) and Systemic Inflammation in Video-Assisted Thoracoscopic Surgery: A Randomized Controlled Trial","IMPROVE-VATS","Inclusion Criteria:\n\n* Elective video-assisted thoracoscopic surgery (VATS) planned\n* Age 18-70 years\n* ASA physical status I-III\n* Body mass index (BMI) \\\u003C35 kg\u002Fm²\n\nExclusion Criteria:\n\n* Coagulopathy\n* Opioid dependence or intolerance\n* Allergy to local anesthetics\n* Contraindications to neuraxial blockade\n* Chronic pain history\n* Renal or hepatic failure","ALL","18 Years","70 Years",{"count":91,"type":92},52,"ESTIMATED","INTERVENTIONAL",[95],"NA","This study will compare two different methods of pain management in patients undergoing video-assisted thoracoscopic surgery (VATS). One group will receive a combination of spinal morphine, nerve block, and dexmedetomidine, while the other group will receive a nerve block and dexmedetomidine without spinal morphine. All patients will receive standard pain medications after surgery. The purpose is to see if adding spinal morphine improves pain control and recovery after surgery.",[98],"Postoperative Pain Management in Video-Assisted Thoracoscopic Surgery",[100,101,24,102,103],"Video-Assisted Thoracoscopic Surgery","Postoperative Analgesia","Patient-Controlled Analgesia (PCA)","Thoracic Surgery Pain Management","2026-02-03",{"date":106,"type":107},"2026-02-05","ACTUAL",{"date":109,"type":107},"2025-12-01",{"date":111,"type":92},"2026-06-02",{"name":5,"class":6},2]