[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100627108":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":22,"locations":32,"responsibleParty":50,"collaborators":10,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":10,"eligibilityCriteria":58,"healthyVolunteers":54,"sex":59,"minAge":60,"maxAge":10,"enrollmentInfo":61,"targetDuration":64,"studyType":65,"phases":10,"briefSummary":66,"conditions":67,"keywords":70,"overallStatus":72,"whyStopped":10,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":82},{"fullName":5,"class":6},"The First Affiliated Hospital with Nanjing Medical University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"IVL group",null,"Patients in the IVL group all received intravascular lithotripsy treatment.",[13],"Procedure: percutaneous coronary intervention",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"PROCEDURE","percutaneous coronary intervention","All enrolled patients underwent Intravascular Lithotripsy (IVL) and Percutaneous Coronary Intervention (PCI) under guideline-directed management.",[9],[21],"intravascular lithotripsy",[23,28],{"name":24,"role":25,"phone":26,"phoneExt":10,"email":27},"Chunjian Li, PHD","CONTACT","13701465229","lijay@njmu.edu.cn",{"name":29,"role":25,"phone":30,"phoneExt":10,"email":31},"Lei Xu, MD","18262632237","xu.lei720@163.com",[33],{"facility":34,"status":10,"city":35,"state":36,"zip":37,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"First Affiliated Hospital of Nanjing Medical University","Nanjing","Jiangsu","210000","China","CN",{"type":41,"coordinates":42},"Point",[43,44],118.77778,32.06167,{"lat":44,"lon":43},[47],{"name":48,"role":25,"phone":49,"phoneExt":10,"email":27},"Li chunjian, Phd","+86 13701465229",{"type":51,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100627108","intravascular-imaging-guided-intravascular-lithotripsy-for-severe-coronary-calcified-lesions-100627108",false,"NCT07444346","Intravascular Imaging-Guided Intravascular Lithotripsy for Severe Coronary Calcified Lesions.","Intravascular Imaging-Guided Intravascular Lithotripsy for Severe Coronary Calcified Lesions, a Prospective,Observational, Single-center Registry Study.","Inclusion Criteria:\n\n1. Patients with coronary angiography showing vessel diameter stenosis ≥ 70% and moderate to severe calcification;\n2. Reference vessel diameter ≥ 2.5 mm;\n3. Signed informed consent form.\n\nExclusion Criteria:\n\n1. Patients with comorbid conditions such as malignant tumors and an expected lifespan of less than 1 year;\n2. Patients with hemodynamic instability;\n3. Patients classified as New York Heart Association (NYHA) functional class IV;\n4. Any other conditions deemed by the investigator as unsuitable for enrollment.","ALL","18 Years",{"count":62,"type":63},200,"ESTIMATED","6 Months","OBSERVATIONAL","This study aims to investigate the efficacy and safety of intravascular lithotripsy (IVL) balloon in treating coronary calcified lesions at our center.",[68,69],"Coronary Artery Calcification","Coronary Artery Disease",[21,71,17],"coronary artery calcification","NOT_YET_RECRUITING","2026-02-26",{"date":75,"type":76},"2026-03-02","ACTUAL",{"date":78,"type":63},"2026-02-10",{"date":80,"type":63},"2027-01-30",{"name":5,"class":6},1]