[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100591337":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":20,"locations":30,"responsibleParty":47,"collaborators":10,"id":49,"slug":50,"hasResults":51,"nctId":52,"briefTitle":53,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":51,"sex":56,"minAge":10,"maxAge":10,"enrollmentInfo":57,"targetDuration":10,"studyType":60,"phases":10,"briefSummary":61,"conditions":62,"keywords":65,"overallStatus":70,"whyStopped":10,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":80},{"fullName":5,"class":6},"Guangdong Provincial People's Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"ICG Fluorescence Group",null,"For patients with bone and soft tissue tumors, indocyanine green (ICG) is administered intravenously preoperatively. A tailored surgical plan is developed based on tumor location, anatomical complexity, histological subtype, and tumor stage. During surgery, a near-infrared (NIR) fluorescence imaging system is utilized for real-time intraoperative imaging and fluorescence-guided verification of tumor margins. Postoperatively, pathological examination of resected specimens is performed, and the positive margin rate is calculated based on histopathological findings.",[13],"Drug: Indocyanine green (ICG)",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"DRUG","Indocyanine green (ICG)","Indocyanine green (ICG; National Drug Approval No. H20213567, Ruida Pharmaceuticals) is administered intravenously 24 hours preoperatively at a dose of 2 mg\u002Fkg. The drug is dissolved in 250 mL of normal saline using a light-protected infusion set and infused at a constant rate over 60 minutes. Alternatively, a 0.5 mg\u002Fkg dose may be administered via IV infusion 1-3 hours before surgery.",[9],[21,26],{"name":22,"role":23,"phone":24,"phoneExt":10,"email":25},"Zhang Yu, Ph.D.","CONTACT","8613602744495","luck_2001@126.com",{"name":27,"role":23,"phone":28,"phoneExt":10,"email":29},"Yan Yuan, Ph.D.","8613178504143","Yuan_Yan2021@163.com",[31],{"facility":5,"status":10,"city":32,"state":33,"zip":34,"country":35,"countryCode":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"Guangzhou","Guangdong","516008","China","CN",{"type":38,"coordinates":39},"Point",[40,41],113.25,23.11667,{"lat":41,"lon":40},[44,46],{"name":22,"role":23,"phone":45,"phoneExt":10,"email":25},"+8613178504143",{"name":27,"role":23,"phone":10,"phoneExt":10,"email":29},{"type":48,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100591337","investigation-into-the-safety-and-efficacy-of-icg-labeled-fluorescence-imaging-technology-in-guiding-the-resection-of-bone-and-soft-tissue-tumors-100591337",false,"NCT06979115","Investigation Into the Safety and Efficacy of ICG-Labeled Fluorescence Imaging Technology in Guiding the Resection of Bone and Soft Tissue Tumors","ICG-BST","Inclusion Criteria:\n\n1. Histologically confirmed diagnosis of bone and soft tissue tumors (according to the WHO Classification of Tumours of Soft Tissue and Bone, 4th Edition).\n2. Medically fit to undergo surgical treatment based on preoperative evaluation.\n3. Absence of cardiovascular, anesthesia-related, or other surgical contraindications.\n\nExclusion Criteria:\n\n1. Presence of severe or chronic kidney, liver, or pulmonary diseases.\n2. Autonomous thyroid nodules or allergy to iodine\u002Fshellfish.\n3. Deemed unable to tolerate surgery based on preoperative evaluation.","ALL",{"count":58,"type":59},40,"ESTIMATED","OBSERVATIONAL","Investigate the application protocol, feasibility, and efficacy of indocyanine green (ICG)-assisted near-infrared (NIR) fluorescence-guided resection in bone and soft tissue tumors. Assess the incidence of adverse events and evaluate the safety of the protocol.",[63,64],"Bone Neoplasms","Soft Tissue Neoplasms",[66,67,68,69],"Soft tissue neoplasms","Bone neoplasms","Indocyanine green","Near-infrared","NOT_YET_RECRUITING","2025-05-12",{"date":73,"type":74},"2025-05-18","ACTUAL",{"date":76,"type":59},"2025-05-25",{"date":78,"type":59},"2028-12-31",{"name":5,"class":6},1]