[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100597064":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":11,"centralContacts":20,"locations":26,"responsibleParty":39,"collaborators":11,"id":42,"slug":43,"hasResults":44,"nctId":45,"briefTitle":46,"officialTitle":46,"acronym":47,"eligibilityCriteria":48,"healthyVolunteers":44,"sex":49,"minAge":50,"maxAge":51,"enrollmentInfo":52,"targetDuration":11,"studyType":55,"phases":56,"briefSummary":58,"conditions":59,"keywords":62,"overallStatus":29,"whyStopped":11,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":74},{"fullName":5,"class":6},"University of Freiburg","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Venous occlusion pressure measurements","EXPERIMENTAL",null,[13],"Device: venous occlusion pressure Measurement",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":11},"DEVICE","venous occlusion pressure Measurement","non-invasive venous occlusion pressure of a targeted periorbital vein is measured in parallel to clinical standard CSF dyanmic testing including standard CSF infusiontest",[9],[21],{"name":22,"role":23,"phone":24,"phoneExt":11,"email":25},"Katharina Wolf","CONTACT","+4976127050010","katharina.wolf@uniklinik-freiburg.de",[27],{"facility":28,"status":29,"city":30,"state":11,"zip":11,"country":31,"countryCode":32,"cosmosGeoPoint":33,"geoPoint":38,"contacts":11},"Klinik für Neurochirurgie, Universitätsklinikum Freiburg","RECRUITING","Freiburg im Breisgau","Germany","DE",{"type":34,"coordinates":35},"Point",[36,37],7.85222,47.9959,{"lat":37,"lon":36},{"type":40,"investigatorFullName":22,"investigatorTitle":41,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"PRINCIPAL_INVESTIGATOR","Funktionsoberärztin Leiterin der Liquorzirkulations-Ambulanz Fachärztin für Neurologie","100597064","investigation-of-a-new-window-into-intracranial-pressure-venous-occlusion-pressure-of-the-isolated-periorbital-vein-100597064",false,"NCT07053631","Investigation of a New Window Into Intracranial Pressure: Venous Occlusion Pressure of the Isolated Periorbital Vein","VOPxICP","Inclusion Criteria:\n\n* Medical indication to perform routine craniospinal CSF dynamic testing according to standard operative procedures\n* Aged 18-95\n* Willing and able to provide valid signed informed consent\n\nExclusion Criteria:\n\n* Patients with any known ongoing, or history of, abnormal CSF communication\n* Patients with any kind of prior intervention for CSF diversion\n* Patients with acute brain damage within the preceding 6 months\n* Patients with transdural surgery within the preceding 6 months\n* Head wounds or hematoma that could hinder access to measurement site\n* Any known pathological condition linked to the orbital socket influencing venous outflow","ALL","18 Years","95 Years",{"count":53,"type":54},10,"ESTIMATED","INTERVENTIONAL",[57],"NA","Elevated intracranial pressure (ICP) occurs when pressure inside the skull rises above normal levels, potentially leading to brain damage or herniation. Monitoring ICP is critical for managing conditions like brain tumors, traumatic brain injury, and stroke. Current ICP monitoring methods are invasive and carry risks, including infection and brain damage. For less severe cases, lumbar puncture is a safer, less invasive alternative. This study explores the potential of a non-invasive method, using venous pressure near the eye, to estimate ICP. The goal is to assess whether the results from this non-invasive approach are similar to the invasive lumbar CSF pressure measurements.",[60,61],"Indication for CSF Dynamic Testing","Indication for CSF Infusion Test",[63,64],"ICP","non-invasive ICP assessment","2025-07-01",{"date":67,"type":68},"2025-07-08","ACTUAL",{"date":70,"type":68},"2025-04-07",{"date":72,"type":54},"2025-12-08",{"name":5,"class":6},1]