[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100615546":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":15,"locations":21,"responsibleParty":37,"collaborators":10,"id":39,"slug":40,"hasResults":41,"nctId":42,"briefTitle":43,"officialTitle":44,"acronym":10,"eligibilityCriteria":45,"healthyVolunteers":46,"sex":47,"minAge":48,"maxAge":49,"enrollmentInfo":50,"targetDuration":10,"studyType":53,"phases":10,"briefSummary":54,"conditions":55,"keywords":60,"overallStatus":24,"whyStopped":10,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":78},{"fullName":5,"class":6},"Marmara University","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Lipedema group",null,"Participants diagnosed with lipedema based on established clinical criteria, including characteristic bilateral lower-extremity adipose tissue enlargement, pain or tenderness on palpation, easy bruising, and preservation of foot anatomy. Diagnosis is confirmed by a physiatrist or relevant specialist through medical history and physical examination. These participants will undergo radiographic foot assessment, hypermobility evaluation, and functional testing as part of the study protocol.",{"label":13,"type":10,"description":14,"interventionNames":10},"Control group","Age- and BMI-matched female participants presenting with nonspecific foot pain but without a diagnosis or clinical suspicion of lipedema, lymphedema, connective tissue disorders, or systemic inflammatory disease. These individuals will undergo the same radiographic, hypermobility, and functional assessments as the lipedema group, allowing for direct comparison of foot morphology and joint mobility parameters.",[16],{"name":17,"role":18,"phone":19,"phoneExt":10,"email":20},"Gökçenur Yalçın, M.D., PMR Specialist","CONTACT","+90 216 414 05 45","gokce_cihaner@hotmail.com",[22],{"facility":23,"status":24,"city":25,"state":10,"zip":10,"country":26,"countryCode":10,"cosmosGeoPoint":27,"geoPoint":32,"contacts":33},"Marmara University Pendik Training and Research Hospital","RECRUITING","Istanbul","Turkey (Türkiye)",{"type":28,"coordinates":29},"Point",[30,31],28.94966,41.01384,{"lat":31,"lon":30},[34],{"name":35,"role":18,"phone":36,"phoneExt":10,"email":20},"Gökçenur Yalçın","+90 216 625 45 45",{"type":38,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100615546","investigation-of-medial-longitudinal-arch-and-foot-function-in-patients-with-lipedema-100615546",false,"NCT07294014","Investigation of Medial Longitudinal Arch and Foot Function in Patients With Lipedema","Investigation of Medial Longitudinal Arch and Foot Function in Patients With Lipedema: A Cross-Sectional Study","General Inclusion Criteria (Apply to All Participants)\n\n* Female participants\n* Age 18 years or older\n* Able to read and write (literacy requirement)\n* Availability of bilateral lateral foot radiographs obtained within the past 1 year in the hospital PACS system\n* Willing and able to provide written and verbal informed consent\n\nAdditional eligibility criteria for Lipedema Group\n\n\\- Clinical diagnosis of lipedema according to Halk and Damstra criteria.\n\nAdditional eligibility criteria for Control group:\n\n* Female patients presenting with nonspecific foot pain\n* Similar age and BMI range as the lipedema group\n* No clinical diagnosis or suspicion of lipedema\n\nExclusion Criteria (Apply to all participants)\n\n* Pregnancy\n* Illiteracy\n* Inability or unwillingness to provide written and verbal informed consent\n* History of lower extremity fracture, trauma, or orthopedic surgery\n* Diagnosis of diabetes mellitus\n* Known rheumatologic disease\n* Known polyneuropathy or peripheral nerve injury affecting the lower extremities",true,"FEMALE","18 Years","65 Years",{"count":51,"type":52},32,"ESTIMATED","OBSERVATIONAL","Lipedema is a chronic adipose tissue disorder that commonly leads to joint laxity, hypermobility, and functional limitations, yet its impact on foot morphology has not been systematically examined. This case-control study aims to investigate whether patients with lipedema exhibit a higher prevalence of generalized joint hypermobility and foot structural abnormalities-specifically pes planus-compared with age- and BMI-matched controls. Using radiographic measurements (Meary angle and calcaneal inclination angle), clinical hypermobility assessment, and validated functional scales, the study seeks to determine the relationship between lipedema, hypermobility, and foot function.",[56,57,58,59],"Lipedema","Hypermobility Syndrome (Disorder)","Pes Planus","Joint Hypermobility",[61,62,63,64,65,66,67,68],"lipedema","mypermobility","foot function","pes planus","joint hyper mobility","foot morphology","Meary angle","calcaneal inclination angle","2025-12-31",{"date":71,"type":72},"2026-01-02","ACTUAL",{"date":74,"type":52},"2026-01-01",{"date":76,"type":52},"2026-04-01",{"name":5,"class":6},1]