[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100637321":3},{"organization":4,"armGroups":7,"interventions":15,"overallOfficials":31,"centralContacts":32,"locations":38,"responsibleParty":53,"collaborators":31,"id":55,"slug":56,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":59,"acronym":31,"eligibilityCriteria":60,"healthyVolunteers":61,"sex":62,"minAge":63,"maxAge":64,"enrollmentInfo":65,"targetDuration":31,"studyType":68,"phases":69,"briefSummary":71,"conditions":72,"keywords":77,"overallStatus":83,"whyStopped":31,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},{"fullName":5,"class":6},"Northern Arizona University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Experimental Group","EXPERIMENTAL","Trials will take place over-ground and\u002For on a treadmill. Participants will ambulate for up to 40 minutes. Frequent breaks will be provided between trials and conditions to avoid fatigue and a maximum of 15 minutes of continuous ambulation will take place between breaks. When deemed necessary by the research staff or participant, crutches, canes, walkers, an overhead support system, or other ambulation or safety aid will be used to minimize the risk of a severe fall.\n\nList of ambulation activities will include no more than\n\n1. Walking at a mild incline\u002Fdecline (0°-15°) on treadmill or over-ground\n2. Ascending or descending stairs\n3. Stand to sit and sit to stand transitions\n4. All terrain walking over ground\n5. Turning\n6. Any combination of the above-mentioned activities\n\nThe above activities will be performed with the passive prosthesis and the motorized prosthesis in the \"off\", \"transparent\", and \"powered\" configurations.",[13,14],"Device: Passive prosthesis","Device: Motorized prosthesis",[16,25],{"type":17,"name":18,"description":19,"armGroupLabels":20,"otherNames":21},"DEVICE","Passive prosthesis","The participant will perform the study protocol with their \"take home\" prosthesis and\u002For another suitable passive prosthesis.",[9],[22,23,24],"take home prosthesis","control","baseline",{"type":17,"name":26,"description":27,"armGroupLabels":28,"otherNames":29},"Motorized prosthesis","The motorized prosthesis is an experimental device. The device is constructed from plastic and metal. It has motors, sensors, and electronic systems to control the prosthesis to mimic the behavior of a biological joint. The device is determined non-significant risk by the sponsor's Institutional Review Board.",[9],[30],"powered prosthesis",null,[33],{"name":34,"role":35,"phone":36,"phoneExt":31,"email":37},"Dante A Archangeli, PhD","CONTACT","928-421-3563","dante.archangeli@nau.edu",[39],{"facility":5,"status":31,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Flagstaff","Arizona","86001","United States","US",{"type":46,"coordinates":47},"Point",[48,49],-111.65127,35.19807,{"lat":49,"lon":48},[52],{"name":34,"role":35,"phone":36,"phoneExt":31,"email":37},{"type":54,"investigatorFullName":31,"investigatorTitle":31,"investigatorAffiliation":31,"oldNameTitle":31,"oldOrganization":31},"SPONSOR","100637321","investigation-of-motorized-lower-limb-prostheses-100637321",false,"NCT07584707","Investigation of Motorized Lower-limb Prostheses","Inclusion Criteria:\n\n* Individuals age 18 to 85 with or without lower-limb amputation\n* Able to understand and follow simple directions in English based on ability to provide verbal consent\n* Able to walk at least 30 feet with or without a walking aid\n* Able to safely fit into a device configuration and tolerate assistance\n* Individuals with lower-limb amputation must receive physician approval to participate in the study.\n\nExclusion Criteria:\n\n* Any neurological, musculoskeletal (other than lower-limb amputation) or cardiorespiratory injury, health condition (including pregnancy), or diagnosis that would affect the ability to walk as directed for short periods of time.\n* Participant or caregiver report that the perspective participant's physician has recommended that they not engage in moderate intensity walking exercise.\n* Subject mass greater than the engineered limit of the device (90 kg or 198 lbs) Note: No exclusions will be made on the basis of race, gender or ethnic background.",true,"ALL","18 Years","85 Years",{"count":66,"type":67},20,"ESTIMATED","INTERVENTIONAL",[70],"NA","The goal of this clinical trial is to learn if a motorized prosthesis can improve mobility in individuals with amputation. The main question it aims to answer is:\n\n* Does motorized prosthesis improve ambulation speed, balance, control, or efficiency when performing everyday activities?\n* What problems arise when using a motorized prosthesis? Researchers will compare mobility of the participants when using and not using the motorized prosthesis to see if mobility and\u002For function improves.\n\nParticipants will perform various activities with and without the motorized prosthesis including:\n\n* Walking at a mild incline\u002Fdecline (0°-15°) on treadmill or over-ground\n* Ascending or descending stairs\n* Stand to sit and sit to stand transitions\n* All terrain walking over ground\n* Turning\n* Any combination of the above-mentioned activities",[73,74,75,76],"Ambulation With the \"Take Home\" or Passive Prosthesis","Ambulation With the Motorized Prosthesis in the \"Off\" Configuration","Ambulation With the Motorized Prosthesis in the \"Transparent\" Condition","Ambulation With the Motorized Prosthesis in the \"Powered\" Condition",[78,79,80,81,82],"motorized prosthesis","ambulation","biomechanics","mobility","amputation","NOT_YET_RECRUITING","2026-05-07",{"date":86,"type":87},"2026-05-13","ACTUAL",{"date":89,"type":67},"2026-04-16",{"date":91,"type":67},"2029-03-15",{"name":5,"class":6},1]