[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100530594":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":30,"centralContacts":34,"locations":40,"responsibleParty":57,"collaborators":30,"id":61,"slug":62,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":30,"eligibilityCriteria":67,"healthyVolunteers":63,"sex":68,"minAge":69,"maxAge":70,"enrollmentInfo":71,"targetDuration":30,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":80,"overallStatus":42,"whyStopped":30,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"Umraniye Education and Research Hospital","OTHER_GOV",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"PROXİMAL ADDUKTOR CANAL BLOCK GROUP","ACTIVE_COMPARATOR","Patients are placed in the supine position and a high-frequency linear probe is inserted for a cross-sectional image of the groin and thigh. The femoral nerve is identified in the short axis near the inguinal crease and the ultrasound transducer is placed caudally beyond the femoral triangle. The location of the proximal block is determined where the superficial femoral artery passes under the medial border of the sartorius muscle (usually 8-12 cm distal to the inguinal crease). Using the in-plane technique, a 100 mm peripheral nerve block needle is advanced until the tip of the needle passes the sartorius muscle and enters the adductor canal from the lateral side of the superficial femoral artery, and 20 mL 0.375% Bupivacaine is administered. To verify block success, sensory function is assessed by pinprick testing along the saphenous nerve distribution by comparing the pinprick sensation to the unaffected limb.",[13],"Other: ADDUKTOR CANAL BLOCK",{"label":15,"type":10,"description":16,"interventionNames":17},"DİSTAL ADDUKTOR CANAL BLOCK GROUP","Patients are placed in the supine position, the mid-thigh point is determined as half the distance between the groin crease and the top of the patella. After the mid-thigh mark is marked with a sterile marking pen, the ultrasound transducer is positioned for a transverse view of the adductor canal into the mid-thigh. Under USG imaging, the femoral artery and saphenous nerve are identified. The distal position is determined where the USG probe moves away from the sartorius muscle of the femoral artery and proceeds deep into the adductor hiatus, and a 100 mm block needle passes the sartorius muscle with an in plane technique and 20 mL 0.375% Bupivacaine is administered to the lateral side of the femoral artery and saphenous nerve.",[13],{"label":19,"type":20,"description":21,"interventionNames":22},"CONTROL GROUP","SHAM_COMPARATOR","No nerve block procedure is applied to patients.",[23],"Other: CONTROL GROUP",[25,31],{"type":26,"name":27,"description":28,"armGroupLabels":29,"otherNames":30},"OTHER","ADDUKTOR CANAL BLOCK","All patients who will undergo adductor canal block are sedated with midazolam 0.03 mg\u002Fkg in the preoperative preparation room, after standard monitoring. After 2-3 ml skin infiltration with 2% lidocaine under sterile conditions, a block is applied under USG guidance.To verify block success, sensory function is assessed by pinprick testing along the saphenous nerve distribution by comparing the pinprick sensation to the unaffected limb.All patients are monitored in the operating room and in a sitting position, 10-20 mg (2-4 ml) of heavy marcaine (0.5% bupivacaine hydrochloride and dextrose monohydrate) is applied to the subarachnoid space by entering the L3-4 or L4-5 space with a 25-gauge Whitrace needle.For postoperative multimodal analgesia, which is routinely applied to all patients, intravenous PCA (patient controlled analgesia )tramadol and paracetamol 10 mg \u002F kg iv (8 hours apart) will be given.",[15,9],null,{"type":26,"name":19,"description":32,"armGroupLabels":33,"otherNames":30},"No nerve block procedure is applied to patients.All patients are monitored in the operating room and in a sitting position, 10-20 mg (2-4 ml) of heavy marcaine (0.5% bupivacaine hydrochloride and dextrose monohydrate) is applied to the subarachnoid space by entering the L3-4 or L4-5 space with a 25-gauge Whitrace needle.For postoperative multimodal analgesia, which is routinely applied to all patients, intravenous PCA (patient controlled analgesia) tramadol 50 mg at 10 mg \u002F hour basal rate after loading (20 mg bolus dose + 30 minutes lock time) and paracetamol 10 mg \u002F kg iv (8 hours apart) will be given.",[19],[35],{"name":36,"role":37,"phone":38,"phoneExt":30,"email":39},"Zeliha TUNCEL","CONTACT","+90 505 357 74 83","zelihalara@yahoo.com",[41],{"facility":5,"status":42,"city":43,"state":44,"zip":45,"country":46,"countryCode":30,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"RECRUITING","Istanbul","Umraniye","34734","Turkey (Türkiye)",{"type":48,"coordinates":49},"Point",[50,51],28.94966,41.01384,{"lat":51,"lon":50},[54],{"name":55,"role":37,"phone":56,"phoneExt":30,"email":39},"ZELİHA TUNCEL, ass prof","5053577483",{"type":58,"investigatorFullName":59,"investigatorTitle":60,"investigatorAffiliation":5,"oldNameTitle":30,"oldOrganization":30},"PRINCIPAL_INVESTIGATOR","Zeliha Alicikus","head of Anesthesia and reanimation","100530594","investigation-of-the-effect-of-proximal-and-distal-adductor-canal-block-in-knee-replacement-surgery-100530594",false,"NCT06188806","Investigation of the Effect of Proximal and Distal Adductor Canal Block in Knee Replacement Surgery","Investigation of the Effect of Proximal and Distal Adductor Canal Block on Pain Control and Functional Mobility in Total Knee Prosthesis Surgery Performed Under Spinal Anesthesia","Inclusion Criteria:\n\n* Medications for unilateral TKA surgery\n\n  * Patients aged 18-85\n  * ASA 1-3\n\nExclusion Criteria:\n\n* Patients under 18 years of age and over 85 years of age\n* Patients with ASA 4 and above\n* Patients with cognitive impairment\n* Patients with application site infection\n* Patients allergic to local anesthesia\n* Patients receiving anticoagulant therapy\n* Patients with bleeding diathesis\n* Patients with chronic opioid or substance use\n* Patients with insulin-dependent diabetes mellitus\n* patients with neuropathy\n\n  * patients with hepatic or renal failure\n* Patients who do not accept the procedure to be applied","ALL","18 Years","85 Years",{"count":72,"type":73},78,"ESTIMATED","INTERVENTIONAL",[76],"NA","to investigate the effect of adductor canal block applied with two different approaches in the treatment of pain after TKA surgery on pain control and functional mobility.",[79],"Knee Osteoarthritis",[81],"adduktor canal block,knee artroplasti,postoperative pain","2025-11-16",{"date":84,"type":85},"2025-11-19","ACTUAL",{"date":87,"type":85},"2023-11-10",{"date":89,"type":73},"2026-03-30",{"name":5,"class":6},1]