[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100623147":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":18,"centralContacts":25,"locations":35,"responsibleParty":52,"collaborators":18,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":18,"eligibilityCriteria":62,"healthyVolunteers":58,"sex":63,"minAge":18,"maxAge":18,"enrollmentInfo":64,"targetDuration":18,"studyType":67,"phases":68,"briefSummary":70,"conditions":71,"keywords":73,"overallStatus":75,"whyStopped":18,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},{"fullName":5,"class":6},"Semmelweis University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"ciNPWT","EXPERIMENTAL","Group of patients being treated with prophylactic NPWT after emergency laparotomy.",[13],"Device: Prophylactic\u002FIncisional Negative Pressure Wound Therapy",{"label":15,"type":16,"description":17,"interventionNames":18},"Control","NO_INTERVENTION","Group of patients being treated with \"regular\" wound dressing.",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"DEVICE","Prophylactic\u002FIncisional Negative Pressure Wound Therapy","Negative Pressure Wound Therapy device used on closed laparotomy wound to prevent SSI.",[9],[26,31],{"name":27,"role":28,"phone":29,"phoneExt":18,"email":30},"Balázs Bánky","CONTACT","+36-20-825-8915","bankybalazs@gmail.com",{"name":32,"role":28,"phone":33,"phoneExt":18,"email":34},"Andras Herczeg","+36-20-670-1721","herczeg.andras.ivan@semmelweis.hu",[36],{"facility":37,"status":18,"city":38,"state":18,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"Semmelweis University, Department of Surgery, Transplantation and Gastroenterology","Budapest","1082","Hungary","HU",{"type":43,"coordinates":44},"Point",[45,46],19.04045,47.49835,{"lat":46,"lon":45},[49,51],{"name":50,"role":28,"phone":29,"phoneExt":18,"email":30},"Balazs Banky",{"name":32,"role":28,"phone":33,"phoneExt":18,"email":34},{"type":53,"investigatorFullName":54,"investigatorTitle":55,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"PRINCIPAL_INVESTIGATOR","Dr. Herczeg András","surgeon specialist","100623147","investigation-of-the-effectiveness-of-prophylactic-npwt-cinpwt-in-high-risk-diabetic-patients-with-acute-laparotomy-wounds-100623147",false,"NCT07392853","Investigation of the Effectiveness of Prophylactic NPWT (ciNPWT) in High-risk Diabetic Patients With Acute Laparotomy Wounds","Investigation of the Effectiveness of Prophylactic NPWT (ciNPWT) in High-risk Diabetic Patients With Acute Laparotomy Wounds - A Randomized, Prospective Clinical Trial","Inclusion Criteria:a (all criteria must apply simultaneously):\n\n* Age ≥18 years,\n* Undergoing urgent abdominal surgery,\n* Diagnosis of diabetes mellitus either already present or newly diagnosed at admission\n* High SSI risk. We consider a patient to be at high SSI risk if the operating surgeon categorizes the patient as high risk, and the patient is classified in the III-IV cleanliness category with an open abdominal surgical procedure (laparotomy). \"High SSI risk\" may also be assessed individually based on existing severe risk factors or using an SSI risk calculator (patients with a normal laparotomy SSI risk more than 3 times the baseline are eligible).\n\nExclusion Criteria: (any of the following):\n\n* Pregnancy,\n* Disseminated cancer (irresectable distant metastasis, peritoneal carcinomatosis),\n* Life expectancy of less than 30 days,\n* Refusal to participate in the study.","ALL",{"count":65,"type":66},110,"ESTIMATED","INTERVENTIONAL",[69],"NA","The aim of this study is to evaluate the effectiveness of prophylactic Negative Pressure Wound Therapy (NPWT) in patients with diabetes mellitus undergoing laparotomy who are at high risk for Surgical Site Infections (SSI). In addition to clinical efficacy, the investigators also plan a cost effectiveness analysis to assess the applicability of this relatively high-cost intervention in a domestic healthcare setting.",[72],"Diabetes (Insulin-requiring, Type 1 or Type 2)",[74,9],"abdominal surgery, SSI, diabetes, emergency surgery","NOT_YET_RECRUITING","2026-01-30",{"date":78,"type":79},"2026-02-06","ACTUAL",{"date":81,"type":66},"2026-02-22",{"date":83,"type":66},"2026-03-22",{"name":5,"class":6},1]