[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100638103":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":24,"centralContacts":25,"locations":31,"responsibleParty":48,"collaborators":24,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":24,"eligibilityCriteria":58,"healthyVolunteers":54,"sex":59,"minAge":60,"maxAge":61,"enrollmentInfo":62,"targetDuration":24,"studyType":65,"phases":66,"briefSummary":68,"conditions":69,"keywords":24,"overallStatus":34,"whyStopped":24,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":80},{"fullName":5,"class":6},"University Hospital, Bonn","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Low Load","EXPERIMENTAL","Low Load (LL-BFR) The first group will perform cycle ergometer training with BFR at a low individual intensity (40% of heart rate reserve \\[HRR\\]) as the first session. One week later, the patients will complete the second exercise session using the protocol of the \"HL-BFR\" group.",[13],"Device: Cycling BFR",{"label":15,"type":10,"description":16,"interventionNames":17},"High Load","High Load (HL-BFR) The second group will perform cycle ergometer training with BFR at a higher individual intensity (60% of heart rate reserve \\[HRR\\]) as the first session. One week later, the patients will complete the second exercise session using the protocol of the \"LL-BFR\" group.",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"DEVICE","Cycling BFR","Cycling ergometer with blood flow restriction",[15,9],null,[26],{"name":27,"role":28,"phone":29,"phoneExt":24,"email":30},"Alexander Franz, Dr. med., B.Sc.","CONTACT","+491703750718","alexander.franz@ukbonn.de",[32],{"facility":33,"status":34,"city":35,"state":36,"zip":37,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"University Hospital Bonn","RECRUITING","Bonn","North Rhine-Westphalia","53127","Germany","DE",{"type":41,"coordinates":42},"Point",[43,44],7.09549,50.73438,{"lat":44,"lon":43},[47],{"name":27,"role":28,"phone":29,"phoneExt":24,"email":30},{"type":49,"investigatorFullName":50,"investigatorTitle":51,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"PRINCIPAL_INVESTIGATOR","Alexander Franz","Dr. med., B.Sc.","100638103","investigation-of-the-individual-fatigue-response-during-blood-flow-restriction-training-100638103",false,"NCT07611526","Investigation of the Individual Fatigue Response During Blood Flow Restriction Training","Investigation of the Individual Fatigue Response During Blood Flow Restriction Training on a Cycle Ergometer Following Orthopedic Surgical Interventions","Inclusion Criteria:\n\n* Elective TKA caused by osteoarthritis of the knee\n* Ability to perform cycling exercise\n* Participant of the Rehab center\n\nExclusion Criteria:\n\n* Open Wounds\n* Iatrogenic Vessel Changes (e.g. Bypasses, Stenting)\n* Sickle Cell Anemia","ALL","18 Years","85 Years",{"count":63,"type":64},20,"ESTIMATED","INTERVENTIONAL",[67],"NA","The aim of the present pilot study is to investigate the feasibility of an exercise pressure response approach for assessing physiological strain during BFR training in a clinically supervised setting. Patients undergoing rehabilitation following total knee arthroplasty (TKA) will be included. The results are intended to contribute to an improved evaluation of load management during BFR training.",[70],"Total Knee Anthroplasty","2026-06-27",{"date":73,"type":74},"2026-07-01","ACTUAL",{"date":76,"type":74},"2026-06-26",{"date":78,"type":64},"2027-03-31",{"name":5,"class":6},1]