[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100492628":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":26,"centralContacts":30,"locations":36,"responsibleParty":57,"collaborators":10,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":10,"eligibilityCriteria":65,"healthyVolunteers":61,"sex":66,"minAge":67,"maxAge":68,"enrollmentInfo":69,"targetDuration":72,"studyType":73,"phases":10,"briefSummary":74,"conditions":75,"keywords":10,"overallStatus":38,"whyStopped":10,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":86},{"fullName":5,"class":6},"University Hospital of North Norway","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Sepsis patients",null,"Patients admitted to the intensive care unit with sepsis diagnosed or suspected",[13],"Drug: Para Aminohippurate",{"label":15,"type":10,"description":16,"interventionNames":17},"Surgical patients","Previously healthy patients who are operated for colon cancer with laparoscopic technique.",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"DRUG","Para Aminohippurate","Measurements of renal plasma flow and glomerular filtration rate",[9,15],[25],"iohexol",[27],{"name":28,"affiliation":5,"role":29},"Lars MG Ytrebø","PRINCIPAL_INVESTIGATOR",[31],{"name":32,"role":33,"phone":34,"phoneExt":10,"email":35},"Lars M Ytrebo, MD PhD","CONTACT","+4790788058","lars.marius.ytrebo@unn.no",[37],{"facility":5,"status":38,"city":39,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"RECRUITING","Tromsø","Troms","9038","Norway","NO",{"type":45,"coordinates":46},"Point",[47,48],18.95508,69.6489,{"lat":48,"lon":47},[51,54],{"name":52,"role":33,"phone":53,"phoneExt":10,"email":35},"Lars M Ytrebø, MD PhD","+47 90788058",{"name":55,"role":56,"phone":10,"phoneExt":10,"email":10},"Kjellbjorn Jakobsen, MD","SUB_INVESTIGATOR",{"type":58,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100492628","investigations-into-sepsis-associated-acute-kidney-injury-100492628",false,"NCT05694624","Investigations Into Sepsis-associated Acute Kidney Injury","Investigations Into the Mechanisms for Bioenergetic Failure in Sepsis-associated Acute Kidney Injury","Inclusion Criteria sepsis group:\n\n* Sepsis diagnosed or suspected\n* Normal premorbid serum creatinine measured or anticipated (if data are not available)\n* Normovolemia as indicated by a pulse pressure variation less than 12%\n\nComparator group\n\n* Previously healthy individuals scheduled for laparoscopic colon cancer resection\n* Normal creatinine levels within 3 months before admittance to hospital.\n\n  * Patients admitted to the intensive care unit with sepsis diagnosed or suspected\n  * Previously healthy patients listed for elective colon cancer surgery\n\nExclusion Criteria:\n\n\\-","ALL","18 Years","100 Years",{"count":70,"type":71},20,"ESTIMATED","2 Days","OBSERVATIONAL","In this study the investigators would like to study systemic and regional disturbances in patients with sepsis-associated acute kidney injury and in healthy controls undergoing laparoscopic abdominal surgery. Specifically study metabolic, hemodynamic and oxygen transport variables.",[76],"Acute Kidney Injury","2025-03-18",{"date":79,"type":80},"2025-03-21","ACTUAL",{"date":82,"type":80},"2023-08-14",{"date":84,"type":71},"2026-12-31",{"name":5,"class":6},1]