[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100267656":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":24,"centralContacts":30,"locations":40,"responsibleParty":64,"collaborators":66,"id":74,"slug":75,"hasResults":76,"nctId":77,"briefTitle":78,"officialTitle":78,"acronym":79,"eligibilityCriteria":80,"healthyVolunteers":81,"sex":82,"minAge":83,"maxAge":10,"enrollmentInfo":84,"targetDuration":10,"studyType":87,"phases":10,"briefSummary":88,"conditions":89,"keywords":91,"overallStatus":43,"whyStopped":10,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":104},{"fullName":5,"class":6},"Washington University School of Medicine","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Parkinsons Disease",null,"Individuals with Parkinsons Disease",[13],"Radiation: PiB and VAT",{"label":15,"type":10,"description":16,"interventionNames":17},"Healthy Controls","Individuals without Parkinsons Disease",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":10},"RADIATION","PiB and VAT","There is no intervention for this study. The PiB and VAT are used during the PET procedures to help to identify any excessive abnormal proteins in the brain.",[15,9],[25,28],{"name":26,"affiliation":5,"role":27},"Joel S Perlmutter, MD","PRINCIPAL_INVESTIGATOR",{"name":29,"affiliation":10,"role":27},"MD",[31,36],{"name":32,"role":33,"phone":34,"phoneExt":10,"email":35},"Andrea Slavik, RN, BSN","CONTACT","314 273 8313","andreaslavik@wustl.edu",{"name":37,"role":33,"phone":38,"phoneExt":10,"email":39},"Hailee Domash","314 362 6026","domash@wustl.edu",[41],{"facility":42,"status":43,"city":44,"state":45,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"Washington University in St. Louis","RECRUITING","St Louis","Missouri","63110","United States","US",{"type":50,"coordinates":51},"Point",[52,53],-90.19789,38.62727,{"lat":53,"lon":52},[56,60],{"name":57,"role":33,"phone":58,"phoneExt":10,"email":59},"Susan Donovan, BSN","314-362-6026","donovan@wustl.edu",{"name":61,"role":33,"phone":62,"phoneExt":10,"email":63},"Kaleigh Oberndorfer","314 362 0420","kaleigh@wustl.edu",{"type":65,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[67,70,72],{"name":68,"class":69},"National Institutes of Health (NIH)","NIH",{"name":71,"class":69},"National Institute of Neurological Disorders and Stroke (NINDS)",{"name":73,"class":69},"National Institute on Aging (NIA)","100267656","investigations-of-dementia-in-parkinson-disease-100267656",false,"NCT02763683","Investigations of Dementia in Parkinson Disease","PIB","Inclusion Criteria:\n\n* PD patients must exhibit three of the following cardinal signs: rest tremor, rigidity, bradykinesia, or postural instability; or two of these features with one of the first three displaying asymmetry.\n\nExclusion Criteria:\n\n* history of head trauma, major neurological or psychiatric diseases other than Parkinson disease and dementia, e.g. stroke, multiple sclerosis, depression or schizophrenia.\n* severe systemic diseases.\n* inability to lie still for 90 minutes.\n* metallic implants, pacemakers, or any other contraindication to MRI.\n* refusal to consent to brain donation.",true,"ALL","50 Years",{"count":85,"type":86},320,"ESTIMATED","OBSERVATIONAL","The purpose of this study is to use a brain imaging method called Pittsburgh B (PIB) Positron Emission Tomography (PET) and Vesicular Cholinergic Transport (VAT) PET to determine dementia subtypes in patients with Parkinson disease (PD). The ultimate goal of this project is to be able to identify individuals with PD who are at risk of developing dementia, and to distinguish the underlying cause of dementia.",[90],"Parkinsons",[9,92,79,93,94],"PET Imaging","VAT","Dementia","2026-05-06",{"date":97,"type":98},"2026-05-08","ACTUAL",{"date":100,"type":10},"2016-06",{"date":102,"type":86},"2030-03",{"name":5,"class":6},1]