[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100566189":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":21,"locations":30,"responsibleParty":83,"collaborators":20,"id":85,"slug":86,"hasResults":87,"nctId":88,"briefTitle":9,"officialTitle":89,"acronym":20,"eligibilityCriteria":90,"healthyVolunteers":87,"sex":91,"minAge":92,"maxAge":93,"enrollmentInfo":94,"targetDuration":20,"studyType":97,"phases":98,"briefSummary":100,"conditions":101,"keywords":106,"overallStatus":33,"whyStopped":20,"lastUpdateSubmitDate":111,"lastUpdatePostDateStruct":112,"startDateStruct":115,"completionDateStruct":117,"leadSponsor":119,"locationsCount":120},{"fullName":5,"class":6},"Align Technology, Inc.","INDUSTRY",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Invisalign® System with Mandibular Advancement","EXPERIMENTAL","all participants will receive the study device",[13],"Device: Invisalign® System with mandibular advancement featuring occlusal blocks",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"DEVICE","Invisalign® System with mandibular advancement featuring occlusal blocks","Class II correction using the Invisalign® System with mandibular advancement featuring occlusal blocks",[9],null,[22,27],{"name":23,"role":24,"phone":25,"phoneExt":20,"email":26},"Allison Mossing","CONTACT","4083940304","amossing@aligntech.com",{"name":28,"role":24,"phone":20,"phoneExt":20,"email":29},"Karen Srour","kgarcia@aligntech.com",[31,51,67],{"facility":32,"status":33,"city":34,"state":35,"zip":36,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"Astra Orthodontics","RECRUITING","Richmond","British Columbia","BC V7C 5L9","Canada","CA",{"type":40,"coordinates":41},"Point",[42,43],-123.13683,49.17003,{"lat":43,"lon":42},[46,50],{"name":47,"role":24,"phone":48,"phoneExt":20,"email":49},"Dr. Sandra Tai, DDS","(604) 270-7828","sandra@drsandratai.com",{"name":47,"role":24,"phone":20,"phoneExt":20,"email":20},{"facility":52,"status":33,"city":53,"state":54,"zip":55,"country":37,"countryCode":38,"cosmosGeoPoint":56,"geoPoint":60,"contacts":61},"MacKenzie Orthodontics","Saint John","New Brunswick","E2L 1G5",{"type":40,"coordinates":57},[58,59],-66.05616,45.27076,{"lat":59,"lon":58},[62,66],{"name":63,"role":24,"phone":64,"phoneExt":20,"email":65},"Dr. Liliya MacKenzie, DDS","(506) 633-0555","drliliyamackenzie@yahoo.ca",{"name":63,"role":24,"phone":20,"phoneExt":20,"email":20},{"facility":68,"status":33,"city":69,"state":70,"zip":71,"country":37,"countryCode":38,"cosmosGeoPoint":72,"geoPoint":76,"contacts":77},"Discover Orthodontics","Brampton","Ontario","L6Z 4N5",{"type":40,"coordinates":73},[74,75],-79.76633,43.68341,{"lat":75,"lon":74},[78,82],{"name":79,"role":24,"phone":80,"phoneExt":20,"email":81},"Dr. Bart Iwasiuk, DDS","(905) 846-7846","bartiwasiuk@hotmail.com",{"name":79,"role":24,"phone":20,"phoneExt":20,"email":20},{"type":84,"investigatorFullName":20,"investigatorTitle":20,"investigatorAffiliation":20,"oldNameTitle":20,"oldOrganization":20},"SPONSOR","100566189","invisalign-system-with-mandibular-advancement-100566189",false,"NCT06651944","Invisalign® System with Mandibular Advancement Featuring Occlusal Blocks (MAOB) Post-Market Study","Inclusion Criteria:\n\n• Subject must be eligible for Invisalign treatment with mandibular advancement\n\nExclusion Criteria:\n\n* Subject's dentition not compatible with device or allergy to device materials\n* Subject who is pregnant, has active caries, periodontal disease, TMD, root resorption, has HAE (hereditary angioedema), has been diagnosed with epilepsy or any other seizure disorder","ALL","10 Years","16 Years",{"count":95,"type":96},36,"ESTIMATED","INTERVENTIONAL",[99],"NA","The goal of this clinical trial is to observe study participants' comfort and fit of their aligners with occlusal blocks, as well as evaluate the engagement of the blocks using the Invisalign® System with mandibular advancement featuring occlusal blocks",[102,103,104,105],"Class II Malocclusion","Mandibular Advancement","Mandibular Retrognathism","Excessive Overjet",[102,103,107,108,109,110],"Invisalign","Orthodontics","Occlusal Blocks","Growing Patients","2024-10-21",{"date":113,"type":114},"2024-10-23","ACTUAL",{"date":116,"type":114},"2024-02-14",{"date":118,"type":96},"2026-12-31",{"name":5,"class":6},3]