[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100485289":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":19,"centralContacts":23,"locations":32,"responsibleParty":53,"collaborators":18,"id":55,"slug":56,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":61,"eligibilityCriteria":62,"healthyVolunteers":57,"sex":63,"minAge":64,"maxAge":65,"enrollmentInfo":66,"targetDuration":18,"studyType":69,"phases":70,"briefSummary":72,"conditions":73,"keywords":75,"overallStatus":35,"whyStopped":18,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":86},{"fullName":5,"class":6},"University Medical Center Groningen","OTHER",[8],{"label":9,"type":6,"description":10,"interventionNames":11},"Low iodine diet","Patients recieve a low iodine diet. Consecutive iodine uptake measurements will be made before and after starting this low iodine diet. This study is constructed of only one study arm, and patients will be compared to themselves.",[12],"Behavioral: Low iodine diet",[14],{"type":15,"name":9,"description":16,"armGroupLabels":17,"otherNames":18},"BEHAVIORAL","Before ablation and possible subsequent therapy with 131I, patients have to follow a low iodine diet (LID), reducing the iodine intake \\\u003C 50 mcg per day and thereby depleting the overall iodine store in the body.",[9],null,[20],{"name":21,"affiliation":5,"role":22},"Wouter Zandee, Dr.","PRINCIPAL_INVESTIGATOR",[24,28],{"name":21,"role":25,"phone":26,"phoneExt":18,"email":27},"CONTACT","+31503613731","w.t.zandee@umcg.nl",{"name":29,"role":25,"phone":30,"phoneExt":18,"email":31},"Mirthe Links, BSc.","+31503610973","m.h.links@umcg.nl",[33],{"facility":34,"status":35,"city":36,"state":37,"zip":38,"country":39,"countryCode":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"UMCG","RECRUITING","Groningen","Provincie Groningen","9713GZ","Netherlands","NL",{"type":42,"coordinates":43},"Point",[44,45],6.56667,53.21917,{"lat":45,"lon":44},[48,51],{"name":49,"role":25,"phone":50,"phoneExt":18,"email":27},"Wouter T Zandee, MD PhD","050 361 6161",{"name":52,"role":25,"phone":50,"phoneExt":18,"email":31},"Mirthe H Links, Bsc",{"type":54,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR","100485289","iodine-uptake-after-a-low-iodine-diet-100485289",false,"NCT05599139","Iodine Uptake After a Low Iodine Diet","The Uptake of Radioactive Iodine Before and After a Low Iodine Diet in Patients With Differentiated Thyroid Carcinoma","IULID","Inclusion Criteria:\n\n* Patients, men and women above the age of 18 years, have to be diagnosed with DTC and have to follow a LID prior to the 131I ablation therapy according to the Dutch DTC guideline\n* Patients have to be fit to adhere to the study protocol\n* Patients have to be able to read and understand the Dutch language\n\nExclusion Criteria:\n\n* Age \\\u003C 18 years\n* Patients using amiodarone\n* Patients receiving iodinated contrast \\\u003C 3 months before the LID\n* Pregnancy\n* Patients prepared for ablation therapy with rhTSH\n* Renal impairment, EGFR \\\u003C30ml\u002Fmin\u002F1,73m2","ALL","18 Years","75 Years",{"count":67,"type":68},25,"ESTIMATED","INTERVENTIONAL",[71],"NA","The goal of this clinical trial is to compare the difference in thyroid uptake of a low dose radioactive iodine (10 MBq 123-I or 37 MBq 123-I) in athyreotic patients with differentiated thyroid carcinoma before and after a low iodine diet (LID) of 7 days.\n\nThe main question it aims to answer is:\n\n• What is the difference in iodine uptake before and after a LID of 7 days?\n\nUptake of a low dose of 123-iodine will be measured in participants before and after a low iodine diet of 7 days. Researchers will compare the uptake (%) before and after the LID.",[74],"Differentiated Thyroid Cancer",[9,76],"Iodine uptake","2026-02-05",{"date":79,"type":80},"2026-02-06","ACTUAL",{"date":82,"type":80},"2023-02-22",{"date":84,"type":68},"2026-08-31",{"name":5,"class":6},1]