[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100613519":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":15,"centralContacts":19,"locations":25,"responsibleParty":37,"collaborators":10,"id":40,"slug":41,"hasResults":42,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":10,"eligibilityCriteria":46,"healthyVolunteers":42,"sex":47,"minAge":48,"maxAge":49,"enrollmentInfo":50,"targetDuration":10,"studyType":53,"phases":10,"briefSummary":54,"conditions":55,"keywords":58,"overallStatus":73,"whyStopped":10,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":83},{"fullName":5,"class":6},"Turgutlu State Hospital","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"FTB + iPACK Group",null,"Patients who underwent primary unilateral TKA and received FTB + iPACK block as part of standard clinical care.",{"label":13,"type":10,"description":14,"interventionNames":10},"FTB + PAI Group","Patients who underwent primary unilateral TKA and received FTB + PAI as part of standard clinical care.",[16],{"name":17,"affiliation":5,"role":18},"Aslan","PRINCIPAL_INVESTIGATOR",[20],{"name":21,"role":22,"phone":23,"phoneExt":10,"email":24},"Celil M Aslan, Medical Doctor","CONTACT","+90505534900","mcaslan@outlook.com.tr",[26],{"facility":27,"status":10,"city":28,"state":28,"zip":29,"country":30,"countryCode":10,"cosmosGeoPoint":31,"geoPoint":36,"contacts":10},"Turgutlu State Hospital+","Manisa","45000","Turkey (Türkiye)",{"type":32,"coordinates":33},"Point",[34,35],27.42647,38.61202,{"lat":35,"lon":34},{"type":18,"investigatorFullName":38,"investigatorTitle":39,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Muhammed Celil Aslan","Anesthesiologist","100613519","ipack-block-vs-periarticular-infiltration-for-tka-pain-control-100613519",false,"NCT07267650","iPACK Block vs. Periarticular Infiltration for TKA Pain Control","Postoperative Analgesic Outcomes of iPACK Block Versus Periarticular Infiltration in Total Knee Arthroplasty: A Retrospective Cohort Study","Inclusion Criteria:\n\n* American Society of Anesthesiologists (ASA) physical status II-III.\n* Scheduled for elective, primary, unilateral total knee arthroplasty for osteoarthritis.\n* Able to provide written informed consent.\n\nExclusion Criteria:\n\n* Patient refusal to participate or contraindication to regional anesthesia.\n* Known allergy to any study medications (local anesthetics, NSAIDs, tramadol, morphine, paracetamol).\n* History of chronic opioid use (defined as daily use for \\>3 months)\n* Pre-existing peripheral neuropathy in the operative limb.\n* Severe renal or hepatic insufficiency.\n* Cognitive impairment preventing the use of pain scales or questionnaires.\n* Revision or bilateral knee arthroplasty.","ALL","18 Years","80 Years",{"count":51,"type":52},100,"ESTIMATED","OBSERVATIONAL","This study aims to retrospectively compare two different multimodal analgesic techniques for pain management after total knee arthroplasty (TKA). The primary purpose is to evaluate whether a combination of two specific nerve blocks administered by an anesthesiologist (Femoral Triangle Block + iPACK block) resulted in superior postoperative pain control compared to a hybrid combination of a nerve block and a local infiltration administered by the surgeon (FTB + Periarticular Infiltration \\[PAI\\]).\n\nThe hypothesis is that the FTB + iPACK combination is associated with a significant reduction in Numeric Rating Scale (NRS) pain scores with movement at 24 hours postoperatively. This is a retrospective, observational cohort study conducted at a single center, involving medical records of patients who underwent primary unilateral TKA. Data from patients who received either FTB + iPACK or FTB + PAI as part of their standard clinical care will be extracted and analyzed retrospectively.",[56,57],"Pain, Postoperative","Osteoarthritis, Knee \u002F Osteoarthritis, Hip",[59,60,61,62,63,64,65,66,67,68,69,70,71,72],"Total Knee Arthroplasty","TKA","Postoperative Pain","Pain Management","Analgesia","Nerve Block","Femoral Triangle Block","FTB","iPACK block","Local Infiltration Analgesia","Timed Up and Go Test","Straight Leg Raise","Periarticular Infiltration","Regional Anesthesia","NOT_YET_RECRUITING","2026-05-28",{"date":76,"type":77},"2026-06-01","ACTUAL",{"date":79,"type":52},"2026-05-01",{"date":81,"type":52},"2026-08-01",{"name":5,"class":6},1]