[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100544672":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":10,"locations":15,"responsibleParty":36,"collaborators":40,"id":44,"slug":45,"hasResults":46,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":50,"eligibilityCriteria":51,"healthyVolunteers":52,"sex":53,"minAge":54,"maxAge":55,"enrollmentInfo":56,"targetDuration":59,"studyType":60,"phases":10,"briefSummary":61,"conditions":62,"keywords":10,"overallStatus":18,"whyStopped":10,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":79},{"fullName":5,"class":6},"London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"study controls",null,"Healthy control participants (n=50) aged 80 and older enrolled in the study with no known CVD or history of significant medical problems.",{"label":13,"type":10,"description":14,"interventionNames":10},"cardiovascular disease","Participants with cardiovascular disease (n=150)",[16],{"facility":17,"status":18,"city":19,"state":20,"zip":21,"country":22,"countryCode":23,"cosmosGeoPoint":24,"geoPoint":29,"contacts":30},"London Regional Health Science Centre","RECRUITING","London","Ontario","N6A 5A5","Canada","CA",{"type":25,"coordinates":26},"Point",[27,28],-81.23304,42.98339,{"lat":28,"lon":27},[31],{"name":32,"role":33,"phone":34,"phoneExt":10,"email":35},"Mark Chandy, MD PhD","CONTACT","5196612111","mark.chandy@lhsc.on.ca",{"type":37,"investigatorFullName":38,"investigatorTitle":39,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Mark Chandy","Assistant Professor",[41],{"name":42,"class":43},"Greenstone Biosciences, Inc.","INDUSTRY","100544672","ipsc-biobank-of-biomarkers-diversity-in-cardiovascular-disease-100544672",false,"NCT06371937","iPSC Biobank of Biomarkers Diversity in Cardiovascular Disease","Blood Biomarkers From Ethnically Diverse Cardiovascular Patients","INFERENCE","Inclusion Criteria:\n\n* Adult (18 to 80 years of age)\n* Cardiovascular Disease (CVD)\n* Cerebrovascular Disease (CBD)\n* Peripheral Vascular Disease (PVD)\n* Inherited Arrhythmias\n* Cardiomyopathies\n* Congenital Heart Disease (CHD)\n* Aortopathy\n* Hypertension\n* Cardiometabolic Disease (CMD)\n\nExclusion Criteria:\n\n* Younger than 18 years of age.\n* Patients not able to provide consent.",true,"ALL","18 Years","80 Years",{"count":57,"type":58},200,"ESTIMATED","10 Years","OBSERVATIONAL","The Investigators will create a clinical database and a Biobank of stem cells derived from the blood of participants with cardiovascular disease. The Investigators will recruit participants from diverse racial and ethnic backgrounds with equal representation from both sexes. The Investigators expect to create stem cells and analyze the blood for protein biomarkers and genetic causes of cardiovascular disease. The stem cell biobank and clinical data will be a powerful tool for studying cardiovascular disease.",[63,64,65,66,67,68,69],"Cardiovascular Diseases","Arrythmia","Cardiomyopathies","Heart Failure","Cerebrovascular Accident","Congenital Heart Disease","Cardiometabolic Syndrome","2024-05-28",{"date":72,"type":73},"2024-05-29","ACTUAL",{"date":75,"type":73},"2024-05-01",{"date":77,"type":58},"2033-06-30",{"name":5,"class":6},1]