[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100626448":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":35,"locations":41,"responsibleParty":70,"collaborators":26,"id":74,"slug":75,"hasResults":76,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":80,"eligibilityCriteria":81,"healthyVolunteers":76,"sex":82,"minAge":83,"maxAge":84,"enrollmentInfo":85,"targetDuration":26,"studyType":88,"phases":89,"briefSummary":91,"conditions":92,"keywords":94,"overallStatus":44,"whyStopped":26,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":101,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":108,"locationsCount":109},{"fullName":5,"class":6},"ETH Zurich","OTHER",[8,16],{"label":9,"type":10,"description":11,"interventionNames":12},"Supplement crossover with maize porridge, comparison of iron absorption","EXPERIMENTAL","1 Block:\n\nMaize porridge with labelled ferrous fumarate or ferrous sulphate (54Fe, 57Fe or 58Fe) combined with either MMS with 30 mg of iron, MMS with 60 mg of iron, IFA with 60 mg of iron, given at day 1, day 3 and day 5",[13,14,15],"Dietary Supplement: MMS with 30 mg iron","Dietary Supplement: MMS with 60 mg iron","Dietary Supplement: IFA with 60 mg iron",{"label":17,"type":10,"description":18,"interventionNames":19},"Supplement crossover with water, everyday vs. every other day","Three blocks in randomized order:\n\nBlock 1: Water with labelled ferrous fumarate (54Fe, 57Fe or 58Fe, randomized) combined with MMS with 30 mg of iron given at day 1, day 2\u002F3 (randomized), day 4\n\nBlock 2: Water with labelled ferrous fumarate (54Fe, 57Fe or 58Fe, randomized) combined with MMS with 60 mg of iron given at day 1, day 2\u002F3 (randomized), day 4\n\nBlock 3: Water with labelled ferrous sulphate (54Fe, 57Fe or 58Fe, randomized) combined with IFA with 60 mg of iron given at day 1, day 2\u002F3 (randomized), day 4",[13,14,15],[21,27,31],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DIETARY_SUPPLEMENT","MMS with 30 mg iron","Multiple Micronutrient Supplementation (MMS) with 30 mg of iron given with ferrous fumarate isotope (54Fe, 57Fe, 58Fe)",[9,17],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"MMS with 60 mg iron","Multiple Micronutrient Supplementation (MMS) with 60 mg of iron given with ferrous fumarate isotope (54Fe, 57Fe, 58Fe)",[9,17],{"type":22,"name":32,"description":33,"armGroupLabels":34,"otherNames":26},"IFA with 60 mg iron","Iron Folic Acid (IFA) with 60 mg of iron given with ferrous sulphate isotope (54Fe, 57Fe, 58Fe)",[9,17],[36],{"name":37,"role":38,"phone":39,"phoneExt":26,"email":40},"Laura N Wasserfallen, MSc","CONTACT","+41 76 574 88 52","laura.wasserfallen@pharma.ethz.ch",[42,60],{"facility":43,"status":44,"city":45,"state":46,"zip":26,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"Kwale Sub County Hospital","RECRUITING","Kwale","Kwale County","Kenya","KE",{"type":50,"coordinates":51},"Point",[52,53],39.45206,-4.17375,{"lat":53,"lon":52},[56],{"name":57,"role":38,"phone":58,"phoneExt":26,"email":59},"Suzane Nyilima, MSc","+254 702 836210","suzane.nyilima@gmail.com",{"facility":61,"status":44,"city":62,"state":46,"zip":26,"country":47,"countryCode":48,"cosmosGeoPoint":63,"geoPoint":67,"contacts":68},"Msambweni County Referral Hospital","Msambweni",{"type":50,"coordinates":64},[65,66],39.48265,-4.4619,{"lat":66,"lon":65},[69],{"name":57,"role":38,"phone":58,"phoneExt":26,"email":59},{"type":71,"investigatorFullName":72,"investigatorTitle":73,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Nicole Stoffel","Prof. Dr.","100626448","iron-absorption-from-ifa-and-mms-supplements-in-kenyan-women-during-the-second-trimester-of-pregnancy-100626448",false,"NCT07435766","Iron Absorption From IFA and MMS Supplements in Kenyan Women During the Second Trimester of Pregnancy","Comparing Iron Absorption From Multiple Micronutrient Supplements and Iron-folate Supplements: a Stable Isotope Study in Kenyan Pregnant Women","PROUD","Inclusion Criteria:\n\n* female\n* pregnant at gestational age 12 (±1) weeks (dated by ultrasound)\n* age 18 to 35 y\n* Hb concentration ≥80 g\u002FL\n* absence of significant inflammation\n* body weight \\\u003C80 kg\n* no major chronic diseases\n* no intake of vitamin and mineral supplements outside of this study in the 1-2 weeks between screening and study start and during the study\n* no blood transfusion, blood donation, or significant blood loss over the past 4 months\n\nExclusion Criteria:\n\n* severe anemia (defined as Hb \\\u003C80 g\u002FL)\n* malaria\n* sickle cell disease (SS and SC)\n* hemoglobin C disease (CC).","FEMALE","18 Years","35 Years",{"count":86,"type":87},50,"ESTIMATED","INTERVENTIONAL",[90],"NA","This study evaluates iron absorption from three antenatal supplements, 30 mg MMS, 60 mg MMS, and 60 mg IFA, in 50 pregnant Kenyan women in their second trimester. Using a randomized crossover design and stable iron isotopes, we will compare bioavailability in both fasted and fed states. Additionally, the trial will investigate if daily dosing triggers a hepcidin response that inhibits subsequent absorption, testing whether alternate-day dosing is a more effective strategy for treating iron deficiency.",[93],"Pregnancy",[95,96,97,93,98,99],"Iron Supplements","Dietary Supplements","Iron Deficiency","Stable Iron Isotopes","Iron Absorption","2026-02-20",{"date":102,"type":103},"2026-02-27","ACTUAL",{"date":105,"type":87},"2026-03-02",{"date":107,"type":87},"2026-12-31",{"name":5,"class":6},2]