[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100566870":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":38,"centralContacts":50,"locations":56,"responsibleParty":73,"collaborators":29,"id":76,"slug":77,"hasResults":78,"nctId":79,"briefTitle":80,"officialTitle":81,"acronym":29,"eligibilityCriteria":82,"healthyVolunteers":83,"sex":84,"minAge":85,"maxAge":86,"enrollmentInfo":87,"targetDuration":29,"studyType":90,"phases":91,"briefSummary":93,"conditions":94,"keywords":97,"overallStatus":59,"whyStopped":29,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":101,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":108,"locationsCount":109},{"fullName":5,"class":6},"Tanta University","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"• Group 1: Manual dynamic agitation by matching gutta-percha master cones","ACTIVE_COMPARATOR","matching gutta-percha master cones will be used in up and down motion 2mm amplitude at a frequency of 100 strokes during approximately 1 min in each prepared canal.",[13],"Other: Group1: A matching gutta-percha master cones will be used in up and down motion 2mm amplitude at a frequency of 100 strokes during approximately 1 min in each prepared canal.",{"label":15,"type":10,"description":16,"interventionNames":17},"Group 3: Easy Clean system activation","EC instrument coupled to the countrangle handpiece and operated with a micromotor at approximately 20,000 rotations per minute in continuous rotation.",[18],"Other: Group 3:EasyClean system activation : EC instrument coupled to the countrangle handpiece and operated with a micromotor at approximately 20,000 rotations per minute in continuous rotation.",{"label":20,"type":10,"description":21,"interventionNames":22},"Group 2: XP-endo Finisher activation","XP-endo Finisher used in continuous rotation for 1 minute accompanied with in-and-out movements of approximately 7-mm amplitude will be applied to the instrument according to the manufacturer's recommendations⁸",[23],"Other: Group2: XP-endo Finisher activation: The XP-endo Finisher instrument will be used in continuous rotation for 1 mintute",[25,30,34],{"type":6,"name":26,"description":27,"armGroupLabels":28,"otherNames":29},"Group1: A matching gutta-percha master cones will be used in up and down motion 2mm amplitude at a frequency of 100 strokes during approximately 1 min in each prepared canal.","The first microbial sample (S1) will be taken from the root canal immediately after access cavity preparation and before chemomechanical preparation.Samples will be subjected to bacterial viable count using blood agar. After complete chemomechanical preparation, a second microbial samble (S2) will be taken and managed the same way as S1.After irrigation activation protocol by matching gutta percha master cone , S3 will be collected from each root canal and managed as S1, S2 to evaluate effect of activation techniques on microbial reduction ,canals will be dried with a matching paper point then 1 mL of Iohexol (omnipaque) contrast media will be injected 2mL shorter than WL and activated by a matching gutta percha master cone , a digital radiographic image will be obtained for each tooth with the same angulation as that for WL and then the distance between WL and maximum irrigant penetration will be measured and recorded using SIDEXIS-XG software.",[9],null,{"type":6,"name":31,"description":32,"armGroupLabels":33,"otherNames":29},"Group2: XP-endo Finisher activation: The XP-endo Finisher instrument will be used in continuous rotation for 1 mintute","The first microbial sample (S1) will be taken from the root canal immediately after access cavity preparation and before chemomechanical preparation.Samples will be subjected to bacterial viable count using blood agar. After complete chemomechanical preparation, a second microbial samble (S2) will be taken and managed the same way as S1.After irrigation activation protocol by XP-endo Finisher used in continuous rotation for 1 minute , S3 will be collected from each root canal and managed as S1, S2 to evaluate effect of activation techniques on microbial reduction ,canals will be dried with a matching paper point then 1 mL of Iohexol (omnipaque) contrast media will be injected 2mL shorter than WL and activated by a matching gutta percha master cone , a digital radiographic image will be obtained for each tooth with the same angulation as that for WL and then the distance between WL and maximum irrigant penetration will be measured and recorded using SIDEXIS-XG software.",[20],{"type":6,"name":35,"description":36,"armGroupLabels":37,"otherNames":29},"Group 3:EasyClean system activation : EC instrument coupled to the countrangle handpiece and operated with a micromotor at approximately 20,000 rotations per minute in continuous rotation.","after access cavity preparation and before chemomechanical preparation.Samples will be subjected to bacterial viable count using blood agar. After complete chemomechanical preparation, a second microbial samble (S2) will be taken and managed the same way as S1.After irrigation activation protocol by EasyClean system activation , S3 will be collected from each root canal and managed as S1, S2 to evaluate effect of activation techniques on microbial reduction ,canals will be dried with a matching paper point then 1 mL of Iohexol (omnipaque) contrast media will be injected 2mL shorter than WL and activated by a matching gutta percha master cone , a digital radiographic image will be obtained for each tooth with the same angulation as that for WL and then the distance between WL and maximum irrigant penetration will be measured and recorded using SIDEXIS-XG software.",[15],[39,43,47],{"name":40,"affiliation":41,"role":42},"Ali Mahmoud Farag, Phd","Professor of Endodontics","PRINCIPAL_INVESTIGATOR",{"name":44,"affiliation":45,"role":46},"Dalia Abd Elhameed Sherif, Phd","Lecturer of Endodontics","STUDY_DIRECTOR",{"name":48,"affiliation":49,"role":42},"Kareman Ahmed Ebrahim Eshra, Phd","Professor of clinical Microbiology and Immunology",[51],{"name":52,"role":53,"phone":54,"phoneExt":29,"email":55},"Alaa Samy, bachelor","CONTACT","+201020630414","alaasamy17395@gmail.com",[57],{"facility":58,"status":59,"city":60,"state":29,"zip":29,"country":61,"countryCode":62,"cosmosGeoPoint":63,"geoPoint":68,"contacts":69},"Faculty of Dentistry","RECRUITING","Tanta","Egypt","EG",{"type":64,"coordinates":65},"Point",[66,67],31.00192,30.78847,{"lat":67,"lon":66},[70],{"name":71,"role":53,"phone":72,"phoneExt":29,"email":29},"yara fawzy, master","+201113674317",{"type":42,"investigatorFullName":74,"investigatorTitle":75,"investigatorAffiliation":5,"oldNameTitle":29,"oldOrganization":29},"Alaa Samy Abd Elsabour Alfky","Doctor","100566870","irrigation-activating-techniques-on-irrigant-penetration-depth-and-microbial-reduction-100566870",false,"NCT06660797","Irrigation Activating Techniques on Irrigant Penetration Depth and Microbial Reduction","Effect of Different Irrigation Activating Techniques on Irrigant Penetration Depth and Microbial Reduction in Root Canals (Clinical Study)","Inclusion Criteria:\n\n* • Asymptomatic vital\u002Fnon vital teeth requiring root canal treatment.\n\n  * Teeth with sound periodontal apparatus.\n  * Teeth without pus or inflammatory exudates draining through the canal.\n  * Teeth without anatomic variations.\n  * Teeth with sinus tract.\n\nExclusion Criteria:\n\n* • Patients with any systemic diseases.\n\n  * Pregnant or lactating patients.\n  * Immunocompromised patients.\n  * Apparently thin roots in which apical preparation with #40 or #50 file would be overzealous.\n  * Patient allergic to anything used in this procedure especially rubber dam material and Iohexol (radiographic contrast media).\n\nRetreatment cases. Teeth with calcified canals.",true,"ALL","18 Years","40 Years",{"count":88,"type":89},30,"ESTIMATED","INTERVENTIONAL",[92],"NA","This in-vivo study aim to evaluate effect of different irrigation activating techniques on Irrigant Penetration Depth and Microbial Reduction in root Canals",[95,96],"Irrigation Activation","Endodontic Disease",[98,99],"Different Irrigation Activating Techniques","primary Endodontic Infection cases","2024-10-25",{"date":102,"type":103},"2024-10-28","ACTUAL",{"date":105,"type":103},"2024-06-01",{"date":107,"type":89},"2025-04-01",{"name":5,"class":6},1]