[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100513753":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":35,"centralContacts":39,"locations":48,"responsibleParty":89,"collaborators":10,"id":92,"slug":93,"hasResults":94,"nctId":95,"briefTitle":96,"officialTitle":97,"acronym":10,"eligibilityCriteria":98,"healthyVolunteers":94,"sex":99,"minAge":10,"maxAge":10,"enrollmentInfo":100,"targetDuration":10,"studyType":103,"phases":10,"briefSummary":104,"conditions":105,"keywords":110,"overallStatus":50,"whyStopped":10,"lastUpdateSubmitDate":113,"lastUpdatePostDateStruct":114,"startDateStruct":117,"completionDateStruct":119,"leadSponsor":121,"locationsCount":122},{"fullName":5,"class":6},"ART Fertility Clinics LLC","OTHER",[8,15,18,22],{"label":9,"type":10,"description":11,"interventionNames":12},"AMH \u003C1.3, at least 1 pregnancy or at least 1 miscarriage",null,"Participants will not undergo any additional intervention compared to normal clinical assessment and routine testing of the ovarian reserve, which includes AMH and AFC. Investigators will follow standard stimulation protocols and medications.",[13,14],"Diagnostic Test: Transvaginal ultrasound","Diagnostic Test: Blood test AMH",{"label":16,"type":10,"description":11,"interventionNames":17},"AMH \u003C1.3, at least 1 pregnancy and no miscarriage",[13,14],{"label":19,"type":10,"description":20,"interventionNames":21},"AMH ≥ 1.3, at least 1 pregnancy or at least 1 miscarriage","Participants will not undergo any additional intervention compared to normal clinical assessment and routine testing of the ovarian reserve, which includes AMH and AFC. Investigators will follow standard stimulation protocols and medications.ons.",[13,14],{"label":23,"type":10,"description":11,"interventionNames":24},"AMH ≥1.3, at least 1 pregnancy and no miscarriage",[13,14],[26,31],{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":10},"DIAGNOSTIC_TEST","Transvaginal ultrasound","Transvaginal ultrasound for antral follicle count (AFC) performed on the day of first consultation",[16,9,19,23],{"type":27,"name":32,"description":33,"armGroupLabels":34,"otherNames":10},"Blood test AMH","Measurement of AMH performed on the day of first consultation",[16,9,19,23],[36],{"name":37,"affiliation":5,"role":38},"Laura Melado, PhD","PRINCIPAL_INVESTIGATOR",[40,45],{"name":41,"role":42,"phone":43,"phoneExt":10,"email":44},"Barbara Lawrenz, PhD","CONTACT","+971 800 337845489","barbara.lawrenz@artfertilityclinics.com",{"name":46,"role":42,"phone":43,"phoneExt":10,"email":47},"Jonalyn Edades, RN","jonalyn.edades@artfertilityclinics.com",[49,67,78],{"facility":5,"status":50,"city":51,"state":52,"zip":53,"country":54,"countryCode":55,"cosmosGeoPoint":56,"geoPoint":61,"contacts":62},"RECRUITING","Abu Dhabi","Abu Dhabi Emirate","60202","United Arab Emirates","AE",{"type":57,"coordinates":58},"Point",[59,60],54.39696,24.45118,{"lat":60,"lon":59},[63,65,66],{"name":37,"role":42,"phone":43,"phoneExt":10,"email":64},"laura.melado@artfertilityclinics.com",{"name":46,"role":42,"phone":43,"phoneExt":10,"email":47},{"name":37,"role":38,"phone":10,"phoneExt":10,"email":10},{"facility":68,"status":50,"city":69,"state":10,"zip":10,"country":54,"countryCode":55,"cosmosGeoPoint":70,"geoPoint":74,"contacts":75},"ART Fertility Clinics Al Ain","Al Ain City",{"type":57,"coordinates":71},[72,73],55.76056,24.19167,{"lat":73,"lon":72},[76],{"name":77,"role":42,"phone":43,"phoneExt":10,"email":47},"Anastasia Salame, MD",{"facility":79,"status":50,"city":80,"state":10,"zip":10,"country":54,"countryCode":55,"cosmosGeoPoint":81,"geoPoint":85,"contacts":86},"ART Fertility Clinics Dubai","Dubai",{"type":57,"coordinates":82},[83,84],55.30927,25.07725,{"lat":84,"lon":83},[87],{"name":88,"role":42,"phone":43,"phoneExt":10,"email":47},"Carol Coughlan, PhD",{"type":38,"investigatorFullName":90,"investigatorTitle":91,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Laura Melado","IVF Specialist","100513753","is-decreased-ovarian-reserve-related-to-an-increased-number-of-previous-early-miscarriages-100513753",false,"NCT05969574","Is Decreased Ovarian Reserve Related to an Increased Number of Previous Early Miscarriages?","Is Decreased Ovarian Reserve Related to an Increased Number of Previous Early Miscarriages? A Prospective Observational Study","Inclusion Criteria:\n\n1\\. All participants with at least 1 previous pregnancy, who are assessed in one of our clinics (ART Fertility Clinics Abu Dhabi, Al Ain, Dubai)\n\nExclusion Criteria:\n\n1. Severe male factor (azoospermia, cryptozoospermia, severe oligoasthenoteratozoospermia (OAT))\n2. Severe Endometriosis and adenomyosis based on positive anamnesis or ultrasound performed in our center during the first consultation\n3. Uterine abnormalities (e.g. fibroids, different degrees of uterine septum), diagnosed by ultrasound\n4. History of ovarian surgery, chemotherapy, or radiation therapy\n5. Known genetic disorder or chromosomal abnormality\n6. BMI \\>40Kg\u002Fm2\n7. Currently using hormonal contraception or hormone replacement therapy","FEMALE",{"count":101,"type":102},2059,"ESTIMATED","OBSERVATIONAL","This study aims to explore the potential correlation between decreased ovarian reserve and previous history of early miscarriage.",[106,107,108,109],"Infertility, Female","Miscarriage","Miscarriage, Recurrent","IVF",[111,112,109],"miscarriage","infertility","2026-06-22",{"date":115,"type":116},"2026-06-25","ACTUAL",{"date":118,"type":116},"2023-09-09",{"date":120,"type":102},"2026-12-31",{"name":5,"class":6},3]