[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100574586":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":19,"centralContacts":24,"locations":34,"responsibleParty":73,"collaborators":10,"id":75,"slug":76,"hasResults":77,"nctId":78,"briefTitle":79,"officialTitle":80,"acronym":81,"eligibilityCriteria":82,"healthyVolunteers":77,"sex":83,"minAge":84,"maxAge":10,"enrollmentInfo":85,"targetDuration":10,"studyType":88,"phases":10,"briefSummary":89,"conditions":90,"keywords":92,"overallStatus":56,"whyStopped":10,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":98,"startDateStruct":101,"completionDateStruct":103,"leadSponsor":105,"locationsCount":106},{"fullName":5,"class":6},"Centre Hospitalier Universitaire de la Guadeloupe","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"acute or chronic Auto-Immune Hepatitis patients",null,"For the study, a blood sample will be collected from the patient in order to build up a serological library which allow the search for rare autoAb whose interest has been demonstrated as prognostic factors of the disease",[13],"Other: blood sampling",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"blood sampling","For the study, a blood sample will be collected from the patient in order to do build up a serological library which will allow the search for rare autoAb whose interest has been demonstrated as prognostic factors of the disease.",[9],[20],{"name":21,"affiliation":22,"role":23},"Moana Lemoinne, doctor","chu de pointe à pitre","PRINCIPAL_INVESTIGATOR",[25,30],{"name":26,"role":27,"phone":28,"phoneExt":10,"email":29},"Valérie SOTER, Promotion Unit manager","CONTACT","+590 590 934677","valerie.soter@chu-guadeloupe.fr",{"name":31,"role":27,"phone":32,"phoneExt":10,"email":33},"Eunice NUBRET, Project manager","+590 0590934686","eunice.nubret@chu-guadeloupe.fr",[35,54],{"facility":36,"status":37,"city":38,"state":39,"zip":40,"country":39,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"Hospital of Saint-Antoine","NOT_YET_RECRUITING","Paris","France","75012","FR",{"type":43,"coordinates":44},"Point",[45,46],2.3488,48.85341,{"lat":46,"lon":45},[49,52],{"name":50,"role":27,"phone":10,"phoneExt":10,"email":51},"Sara Lemoinne, doctor","sara.lemoinne@aphp.fr",{"name":53,"role":27,"phone":10,"phoneExt":10,"email":10},"Sara LEMOINNE, Doctor",{"facility":55,"status":56,"city":57,"state":58,"zip":59,"country":39,"countryCode":41,"cosmosGeoPoint":60,"geoPoint":64,"contacts":65},"CHU de Pointe-à Pitre","RECRUITING","Pointe à Pitre","Guadeloupe","97159",{"type":43,"coordinates":61},[62,63],1.98937,44.07984,{"lat":63,"lon":62},[66,70,71],{"name":67,"role":27,"phone":68,"phoneExt":10,"email":69},"Moana GELU-SIMEON, medecine degree,","+590 0590891446","moana.simeon@chu-guadeloupe.fr",{"name":10,"role":27,"phone":10,"phoneExt":10,"email":33},{"name":72,"role":27,"phone":10,"phoneExt":10,"email":10},"Moana GELU-SIMEON, Doctor",{"type":74,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100574586","is-negativity-of-autoantibodies-a-marker-of-severity-in-auto-immune-hepatitis-100574586",false,"NCT06761209","Is Negativity of Autoantibodies a Marker of Severity in Auto-immune Hepatitis?","Is Negativity of Autoantibodies a Marker of Severity in Auto-immune Hepatitis","HAI-NEG","Inclusion Criteria:\n\n* \\- Any patient over 18 years old\n* Patient followed at Hôpital Saint-Antoine or treated for HAI or in Guadeloupe within the framework of the CCRD Filfoie for an acute or chronic AIH under immunosuppressive treatment\n* Patient affiliate or beneficiary of a social security scheme\n* Free, informed and written consent signed by the patient and the investigator\n\n  o exclusion criteria: - Patient under 18 years old\n* Patient not able to give his\u002Fher consent\n* Viral hepatitis: viruses A to E, Epstein-Barr virus, cytomegalovirus and herpes simplex virus\n* Isolated primary biliary cholangitis\n* Isolated primary sclerosing cholangitis\n* Drug-induced liver injury\n* Wilson disease\n* Alcoholic hepatitis\n* Hemochromatosis\n* Sickle cell disease and heart liver\n* Non-alcoholic steato-hepatitis","ALL","18 Years",{"count":86,"type":87},100,"ESTIMATED","OBSERVATIONAL","Evaluate the proportion of seronegative auto-immune hepatitis and a possible relationship with the severity of the disease. Criteria of severity will be defined by corticodependance, corticoresistance and a severe form of the disease at diagnosis (cirrhosis or fulminant hepatitis). In case of predominant seronegative forms, other auto-antibodies related to this auto-immue hepatitis will be searched.",[91],"Auto-immune Hepatitis",[93,94,95,96],"autoantibodies","auto-immune hepatitis","prognosis","afrocaribbean population","2024-12-30",{"date":99,"type":100},"2025-01-07","ACTUAL",{"date":102,"type":100},"2022-07-01",{"date":104,"type":87},"2026-12",{"name":5,"class":6},2]