[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100630718":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":10,"centralContacts":26,"locations":32,"responsibleParty":49,"collaborators":10,"id":51,"slug":52,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":55,"acronym":56,"eligibilityCriteria":57,"healthyVolunteers":53,"sex":58,"minAge":59,"maxAge":10,"enrollmentInfo":60,"targetDuration":10,"studyType":63,"phases":64,"briefSummary":66,"conditions":67,"keywords":10,"overallStatus":34,"whyStopped":10,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":78},{"fullName":5,"class":6},"Hôpital Européen Marseille","OTHER",[8,14],{"label":9,"type":6,"description":10,"interventionNames":11},"Fatigue Syndrome, Chronic",null,[12,13],"Other: Exercise test on ergocycle","Other: Near Infrared Spectroscopy (NIRS)",{"label":15,"type":6,"description":10,"interventionNames":16},"Cardiovascular diseases",[12,13],[18,22],{"type":6,"name":19,"description":20,"armGroupLabels":21,"otherNames":10},"Exercise test on ergocycle","Participants will undergo a standardized exercise test performed on a cycle ergometer. Symptoms will be assessed using questionnaires before the test and during the 7 days following the exercise test.",[15,9],{"type":6,"name":23,"description":24,"armGroupLabels":25,"otherNames":10},"Near Infrared Spectroscopy (NIRS)","Muscle oxygenation will be monitored using Near Infrared Spectroscopy (NIRS) before, during and after exercise",[15,9],[27],{"name":28,"role":29,"phone":30,"phoneExt":10,"email":31},"Myriam BENNANI","CONTACT","0413428351","m.bennani@hopital-europeen.fr",[33],{"facility":5,"status":34,"city":35,"state":10,"zip":10,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"RECRUITING","Marseille","France","FR",{"type":39,"coordinates":40},"Point",[41,42],5.38107,43.29695,{"lat":42,"lon":41},[45,46],{"name":28,"role":29,"phone":30,"phoneExt":10,"email":31},{"name":47,"role":48,"phone":10,"phoneExt":10,"email":10},"Frédérique RETORNAZ","PRINCIPAL_INVESTIGATOR",{"type":50,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100630718","is-post-exertional-symptom-exacerbation-specific-to-patients-with-myalgic-encephalomyelitis--chronic-fatigue-syndrome-a-study-comparing-patients-with-myalgic-encephalomyelitis--chronic-fatigue-syndrome-and-patients-with-cardiac-diseases-who-underwent-an-exercise-test-100630718",false,"NCT07491315","Is Post-exertional Symptom Exacerbation Specific to Patients With Myalgic Encephalomyelitis \u002F Chronic Fatigue Syndrome? A Study Comparing Patients With Myalgic Encephalomyelitis \u002F Chronic Fatigue Syndrome and Patients With Cardiac Diseases Who Underwent an Exercise Test.","MAPEMCAR","Inclusion Criteria:\n\n* Aged ≥ 18 years\n* For patients with Myalgic Encephalomyelitis \u002F Chronic Fatigue Syndrome (ME\u002FCFS): Clinical diagnosis of Myalgic Encephalomyelitis \u002F Chronic Fatigue Syndrome according to the International Consensus Criteria (ICC) 2011.\n* For patients with cardiac diseases : patients referred for an exercise test in the cardiology department for one of the following indications: palpitations, hypertension, exertional dyspnea, chest pain, cornoray artery disease and presence of moderate to severe fatigue defined as a Numerical Rating Scale (NRS) \\> 3\u002F10 during the last 8 days and no diagnosis of Myalgic Encephalomyelitis \u002F Chronic Fatigue Syndrome.\n* Ability to use a computer or digital device required to complete online questionnaires.\n* Having given free and informed written consent\n\nExclusion Criteria:\n\n* Pregnant or breastfeeding woman\n* Persons deprived of their liberty by a judicial or administrative decision.\n* Persons who are subject to a legal protection measure or who are unable to express their consent.","ALL","18 Years",{"count":61,"type":62},80,"ESTIMATED","INTERVENTIONAL",[65],"NA","Myalgic Encephalomyelitis \u002F Chronic Fatigue Syndrome (ME\u002FCFS) is a disease characterized by persistent and unexplained fatigue associated with diffuse pain, sleep disorders, neurocognitive and autonomic symptoms, musculoskeletal manifestations and digestive symptoms. A central feature of this disease is post-exertional symptom exacerbation, also referred to as post-exertional malaise, defined as the worsening or the appearance of symptoms after physical or mental exertion, sometimes even minimal.\n\nSeveral studies have described post-exertional malaise in populations of patients with ME\u002FCFS following a standardized exercise test performed over one or two consecutive days. These studies confirmed the presence of post-exertional malaise in ME\u002FCFS patients compared with healthy controls or patients with multiple sclerosis.\n\nHowever, no data are available evaluating the impact of an exercise test on symptoms in patients referred to cardiology for this examination. Patients with cardiac diseases may also present symptoms such as fatigue, dyspnea or exercise intolerance.\n\nThis study aims to compare post-exertional symptoms in two populations: patients with ME\u002FCFS and patients with cardiac diseases undergoing an exercise test as part of routine clinical evaluation. The study also aims to measure variations in muscle oxyhemoglobin and deoxyhemoglobin concentrations before, during and after exercise using Near Infrared Spectroscopy (NIRS).",[9,68],"Cardiovascular Diseases","2026-06-04",{"date":71,"type":72},"2026-06-08","ACTUAL",{"date":74,"type":72},"2025-06-24",{"date":76,"type":62},"2026-12-24",{"name":5,"class":6},1]