[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100635181":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":36,"centralContacts":41,"locations":50,"responsibleParty":71,"collaborators":26,"id":74,"slug":75,"hasResults":76,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":26,"eligibilityCriteria":80,"healthyVolunteers":76,"sex":81,"minAge":82,"maxAge":83,"enrollmentInfo":84,"targetDuration":26,"studyType":87,"phases":88,"briefSummary":90,"conditions":91,"keywords":94,"overallStatus":53,"whyStopped":26,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":101,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":108,"locationsCount":109},{"fullName":5,"class":6},"Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Test group","EXPERIMENTAL","The test group will receive sham Professional Mechanical Plaque Removal consisting of cleaning the teeth with the same ultrasonic device but applied more than 2 mm away from the gingival margin at baseline.",[13,14],"Behavioral: Optimal oral care regimen","Device: Sham Periodontal Treatment",{"label":16,"type":6,"description":17,"interventionNames":18},"Control group","The control group will receive standard Professional Mechanical Plaque Removal consisting of supra- and subgingival debridement at baseline.",[13,19],"Device: Periodontal Treatment",[21,27,32],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"BEHAVIORAL","Optimal oral care regimen","Both groups will receive the optimal oral care regimen throughout the entire research period. This regimen comprises using a commercially available intelligent toothbrush connected to the Chinese consumer version of an application, receiving targeted oral health messages, and using dental floss.",[16,9],null,{"type":28,"name":29,"description":30,"armGroupLabels":31,"otherNames":26},"DEVICE","Periodontal Treatment","At baseline, the control group will receive standard professional mechanical plaque removal consisting of supra - and subgingival debridement using ultrasonic device.",[16],{"type":28,"name":33,"description":34,"armGroupLabels":35,"otherNames":26},"Sham Periodontal Treatment","At baseline, the test group will receive sham professional mechanical plaque removal consisting of cleaning the teeth with the same ultrasonic device but applied more than 2 mm away from the gingival margin.",[9],[37],{"name":38,"affiliation":39,"role":40},"Maurizio Tonetti, DMD Phd","Shanghai PerioImplant Innovation Center, Ninth People Hospital","PRINCIPAL_INVESTIGATOR",[42,47],{"name":43,"role":44,"phone":45,"phoneExt":26,"email":46},"Rui Gao, Phd","CONTACT","19818987186","gr1015209095@163.com",{"name":38,"role":44,"phone":48,"phoneExt":26,"email":49},"15000102368","maurizio.tonetti@ergoperio.eu",[51],{"facility":52,"status":53,"city":54,"state":55,"zip":56,"country":57,"countryCode":58,"cosmosGeoPoint":59,"geoPoint":64,"contacts":65},"Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine","RECRUITING","Shanghai","Shanghai Municipality","200000","China","CN",{"type":60,"coordinates":61},"Point",[62,63],121.45806,31.22222,{"lat":63,"lon":62},[66,69],{"name":67,"role":44,"phone":68,"phoneExt":26,"email":46},"Rui Gao, BDS, MSc","8615000102368",{"name":70,"role":40,"phone":26,"phoneExt":26,"email":26},"MAurizio Tonetti, DMD PhD",{"type":40,"investigatorFullName":72,"investigatorTitle":73,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Maurizio Tonetti","Professor","100635181","is-professional-tooth-cleaning-necessary-for-managing-gingivitis-gingival-inflammation-if-subjects-use-intelligent-toothbrushes-100635181",false,"NCT07549347","Is Professional Tooth Cleaning Necessary for Managing Gingivitis (Gingival Inflammation) if Subjects Use Intelligent Toothbrushes?","Optimal Oral Care Regimen With or Without Professional Mechanical Plaque Removal in Managing Gingivitis (Gingival Inflammation): A Non-inferiority Randomized Controlled Trial","Inclusion Criteria:\n\n1. ≧18 years old and \\\u003C 65 years old\n2. Gingivitis, Stage I and Localized Stage II Periodontitis\n3. With more than 20 teeth\n4. Agree to use the electronic I-brush with the Oral-B APP\n\nExclusion Criteria:\n\n1. Presence of any systemic disease that can alter the outcome of periodontal treatment\n2. Pregnancy or lactation during the study\n3. Having received antibiotics within the previous 3 months\n4. Having received professional periodontal treatment within the previous 3 months\n5. With ongoing orthodontic treatment","ALL","18 Years","64 Years",{"count":85,"type":86},92,"ESTIMATED","INTERVENTIONAL",[89],"NA","Periodontitis is highly prevalent and develops from plaque-induced gingivitis. Managing gingivitis is key to preventing periodontitis and its complications. Professional mechanical plaque removal (PMPR) with oral hygiene guidance is effective for gingivitis, but large-scale implementation-especially in China-faces challenges such as workforce shortages. Meanwhile, patient compliance with daily oral hygiene remains poor. An optimal oral care regimen featuring an intelligent electric toothbrush (i-Brush) has shown promise in enhancing self-care adherence and efficiency. However, it remains unclear whether PMPR is still necessary when used in conjunction with this optimal oral care regimen. This study aims to verify whether the i-Brush-based regimen is non-inferior to the combination of PMPR and the regimen in improving gingival inflammation in gingivitis and stage I periodontitis.",[92,93],"Gingivitis","Periodontitis",[95,96,97,98,99],"artificial intelligence","internet of things network","oral hygiene instruction","professional mechanical plaque removal","mobile health","2026-04-17",{"date":102,"type":103},"2026-04-24","ACTUAL",{"date":105,"type":103},"2026-03-09",{"date":107,"type":86},"2027-03-01",{"name":5,"class":6},1]