[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100560837":3},{"organization":4,"armGroups":7,"interventions":15,"overallOfficials":10,"centralContacts":25,"locations":34,"responsibleParty":226,"collaborators":10,"id":228,"slug":229,"hasResults":230,"nctId":231,"briefTitle":232,"officialTitle":233,"acronym":10,"eligibilityCriteria":234,"healthyVolunteers":230,"sex":235,"minAge":236,"maxAge":10,"enrollmentInfo":237,"targetDuration":10,"studyType":240,"phases":10,"briefSummary":241,"conditions":242,"keywords":10,"overallStatus":37,"whyStopped":10,"lastUpdateSubmitDate":244,"lastUpdatePostDateStruct":245,"startDateStruct":248,"completionDateStruct":250,"leadSponsor":252,"locationsCount":253},{"fullName":5,"class":6},"Fundación para la Investigación del Hospital Clínico de Valencia","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Case-crossover group",null,"All patients included in the study will undergo preoperative CT (conventional protocol) and 3D-MSP reconstruction. These results will be compared with the results of the surgery and the anatomopathological study. Each patient will be evaluated by both techniques of the study, thus serving as his or her own control.",[13,14],"Procedure: Three dimensional imaging technology (3D-PANC MSP model)","Procedure: Computerized tomography group (conventional CT)",[16,21],{"type":17,"name":18,"description":19,"armGroupLabels":20,"otherNames":10},"PROCEDURE","Three dimensional imaging technology (3D-PANC MSP model)","The processing of the CT images obtained in each center for the creation of the 3D model will be performed centrally by the team of radiologists and computer scientists of the company Cella Medical Solutions. This team will be blinded to the reports of the CT scans.For each patient 4 NCCN check-lists will be filled in without knowing the result of the surgery or the AP study: 2 based on the conventional CT and two based on the 3D-MSP study.",[9],{"type":17,"name":22,"description":23,"armGroupLabels":24,"otherNames":10},"Computerized tomography group (conventional CT)","A multiphase CT (venous phase and pancreatographic phase) with 1mm thick slices and series of images in coronal, axial and sagittal reconstructions will be performed. This CT model will be performed at disease diagnosis and after completion of neoadjuvant chemotherapy treatment. Both CT scans will be independently reported by a radiologist from the hospital of origin. The preoperative CT scan will also be evaluated a posteriori by a radiologist from the sponsoring center with expertise in PAC. Both reports (the one from the radiologist of the center and the one from the radiologist of the sponsoring center) will be used to fill out the imaging study variables sheet based on the latest version of the NCCN 2022 guidelines. The radiologists will not know the outcome of the surgery or the anatomic pathology study at the time of the completion of the report.",[9],[26,31],{"name":27,"role":28,"phone":29,"phoneExt":10,"email":30},"Dimitri Dorcaratto","CONTACT","675441388","dorcaratto.dimitri@gmail.com",{"name":32,"role":28,"phone":10,"phoneExt":10,"email":33},"Marina Garcés","marinagarcesalbir@gmail.com",[35,51,63,76,85,94,103,115,127,139,148,160,172,184,196,208,217],{"facility":36,"status":37,"city":38,"state":10,"zip":10,"country":39,"countryCode":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"Hospital General de Alicante","RECRUITING","Alicante","Spain","ES",{"type":42,"coordinates":43},"Point",[44,45],-0.48149,38.34517,{"lat":45,"lon":44},[48],{"name":49,"role":28,"phone":10,"phoneExt":10,"email":50},"Celia Villodre Tudela","celivii@gmail.com",{"facility":52,"status":37,"city":53,"state":10,"zip":10,"country":39,"countryCode":40,"cosmosGeoPoint":54,"geoPoint":58,"contacts":59},"Hospital Universitario de Badajoz","Badajoz",{"type":42,"coordinates":55},[56,57],-6.97061,38.87789,{"lat":57,"lon":56},[60],{"name":61,"role":28,"phone":10,"phoneExt":10,"email":62},"Gerardo Blanco","gerardoblanco@unex.es",{"facility":64,"status":37,"city":65,"state":10,"zip":66,"country":39,"countryCode":40,"cosmosGeoPoint":67,"geoPoint":71,"contacts":72},"Hospital del Mar (Barcelona)","Barcelona","08003",{"type":42,"coordinates":68},[69,70],2.15899,41.38879,{"lat":70,"lon":69},[73],{"name":74,"role":28,"phone":10,"phoneExt":10,"email":75},"Fernando Burdío","fburdio@hotmail.com",{"facility":77,"status":37,"city":65,"state":10,"zip":10,"country":39,"countryCode":40,"cosmosGeoPoint":78,"geoPoint":80,"contacts":81},"Hospital Clínic de Barcelona",{"type":42,"coordinates":79},[69,70],{"lat":70,"lon":69},[82],{"name":83,"role":28,"phone":10,"phoneExt":10,"email":84},"Fabio Ausania","f.ausania@googlemail.com",{"facility":86,"status":37,"city":65,"state":10,"zip":10,"country":39,"countryCode":40,"cosmosGeoPoint":87,"geoPoint":89,"contacts":90},"Hospital de Bellvitge",{"type":42,"coordinates":88},[69,70],{"lat":70,"lon":69},[91],{"name":92,"role":28,"phone":10,"phoneExt":10,"email":93},"Juli Busquets","julibusquets67@gmail.com",{"facility":95,"status":37,"city":65,"state":10,"zip":10,"country":39,"countryCode":40,"cosmosGeoPoint":96,"geoPoint":98,"contacts":99},"Hospital German Trias y Puyol",{"type":42,"coordinates":97},[69,70],{"lat":70,"lon":69},[100],{"name":101,"role":28,"phone":10,"phoneExt":10,"email":102},"Esteban Cugat","esteban.cugat@gmail.com",{"facility":104,"status":37,"city":105,"state":10,"zip":10,"country":39,"countryCode":40,"cosmosGeoPoint":106,"geoPoint":110,"contacts":111},"Hospital Nuestra señora de la Candelaria","Candelaria",{"type":42,"coordinates":107},[108,109],-16.37268,28.3548,{"lat":109,"lon":108},[112],{"name":113,"role":28,"phone":10,"phoneExt":10,"email":114},"Betsabé Reyes Correa","reyescorreabetsabe@gmail.com",{"facility":116,"status":37,"city":117,"state":10,"zip":10,"country":39,"countryCode":40,"cosmosGeoPoint":118,"geoPoint":122,"contacts":123},"Hospital General de Castellón","Castellon",{"type":42,"coordinates":119},[120,121],-0.04935,39.98567,{"lat":121,"lon":120},[124],{"name":125,"role":28,"phone":10,"phoneExt":10,"email":126},"Laura Granell","laura_9487@yahoo.es",{"facility":128,"status":37,"city":129,"state":10,"zip":10,"country":39,"countryCode":40,"cosmosGeoPoint":130,"geoPoint":134,"contacts":135},"Hospital Carlos Haya","Málaga",{"type":42,"coordinates":131},[132,133],-4.42034,36.72016,{"lat":133,"lon":132},[136],{"name":137,"role":28,"phone":10,"phoneExt":10,"email":138},"Julio Santoyo","jsantoyovil@gmail.com",{"facility":140,"status":37,"city":129,"state":10,"zip":10,"country":39,"countryCode":40,"cosmosGeoPoint":141,"geoPoint":143,"contacts":144},"Hospital Virgen de la Victoria",{"type":42,"coordinates":142},[132,133],{"lat":133,"lon":132},[145],{"name":146,"role":28,"phone":10,"phoneExt":10,"email":147},"Miguel Ágel Suárez","masuarez59@gmail.com",{"facility":149,"status":37,"city":150,"state":10,"zip":10,"country":39,"countryCode":40,"cosmosGeoPoint":151,"geoPoint":155,"contacts":156},"Hospital Virgen de la Arrixaca","Murcia",{"type":42,"coordinates":152},[153,154],-1.13004,37.98704,{"lat":154,"lon":153},[157],{"name":158,"role":28,"phone":10,"phoneExt":10,"email":159},"Francisco Sánchez-Bueno","sbuenof@um.es",{"facility":161,"status":37,"city":162,"state":10,"zip":10,"country":39,"countryCode":40,"cosmosGeoPoint":163,"geoPoint":167,"contacts":168},"Hospital Son Espases Palma de Mallorca","Palma de Mallorca",{"type":42,"coordinates":164},[165,166],2.65024,39.56939,{"lat":166,"lon":165},[169],{"name":170,"role":28,"phone":10,"phoneExt":10,"email":171},"Rafael Morales Soriano","rafa.morales@telefonica.net",{"facility":173,"status":37,"city":174,"state":10,"zip":10,"country":39,"countryCode":40,"cosmosGeoPoint":175,"geoPoint":179,"contacts":180},"Hospital Virgen del Rocío","Seville",{"type":42,"coordinates":176},[177,178],-5.97317,37.38283,{"lat":178,"lon":177},[181],{"name":182,"role":28,"phone":10,"phoneExt":10,"email":183},"Javier Padillo","javierpadilloruiz@gmail.com",{"facility":185,"status":37,"city":186,"state":10,"zip":10,"country":39,"countryCode":40,"cosmosGeoPoint":187,"geoPoint":191,"contacts":192},"Hospital Juan XXIII Tarragona","Tarragona",{"type":42,"coordinates":188},[189,190],1.24544,41.11905,{"lat":190,"lon":189},[193],{"name":194,"role":28,"phone":10,"phoneExt":10,"email":195},"Laia Estalella Mercadé","laiaestalella2@gmail.com",{"facility":197,"status":37,"city":198,"state":10,"zip":199,"country":39,"countryCode":40,"cosmosGeoPoint":200,"geoPoint":204,"contacts":205},"Hospital Clínico Universitario de Valencia","Valencia","46010",{"type":42,"coordinates":201},[202,203],-0.37966,39.47391,{"lat":203,"lon":202},[206,207],{"name":27,"role":28,"phone":10,"phoneExt":10,"email":30},{"name":32,"role":28,"phone":10,"phoneExt":10,"email":33},{"facility":209,"status":37,"city":198,"state":10,"zip":10,"country":39,"countryCode":40,"cosmosGeoPoint":210,"geoPoint":212,"contacts":213},"Hospital Dr Peset",{"type":42,"coordinates":211},[202,203],{"lat":203,"lon":202},[214],{"name":215,"role":28,"phone":10,"phoneExt":10,"email":216},"Manuel Bellver","bellveroliverm@gmail.com",{"facility":218,"status":37,"city":198,"state":10,"zip":10,"country":39,"countryCode":40,"cosmosGeoPoint":219,"geoPoint":221,"contacts":222},"Hospital La Fe",{"type":42,"coordinates":220},[202,203],{"lat":203,"lon":202},[223],{"name":224,"role":28,"phone":10,"phoneExt":10,"email":225},"Cristina Ballester Ibáñez","cris7balle@yahoo.es",{"type":227,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100560837","is-the-3d-panc-msp-model-superior-to-ct-for-assessing-response-to-neoadjuvant-treatment-in-pca-patients-100560837",false,"NCT06582342","Is the 3D-PANC MSP Model Superior to CT for Assessing Response to Neoadjuvant Treatment in PCA Patients?","Is 3-D Imaging Technology Superior to Computed Tomography in Assessing Response to Neoadjuvant Treatment in Patients With Borderline or Locally Advanced Pancreatic Adenocarcinoma?","Inclusion Criteria:\n\n\\- Patients with a diagnosis of borderline or locally advanced PAC of the head of the pancreas, as defined by the National Comprehensive Cancer Network (NCCN), who have received neoadjuvant treatment and who undergo surgical exploration with resective intent.\n\nExclusion Criteria:\n\n* Patients younger than 18 years of age.\n* Patients under 18 years of age.\n* Disease progression during neoadjuvant treatment.\n* No preoperative CT scan.\n* Refusal to participate in the study.","ALL","18 Years",{"count":238,"type":239},70,"ESTIMATED","OBSERVATIONAL","Prospective multicenter study in which all patients with borderline or locally advanced pancreatic adenocarcioma undergoing neoadjuvant chemotherapy and surgical exploration with curative intent will be included for one year. Preoperative images by traditional CT and 3D-MSP technology will be evaluated, comparing the accuracy variables (sensitivity, specificity, predictive values, area under the curve, concordance index) of both techniques with the gold standard (results of surgery and histopathological analysis).",[243],"Adenocarcinoma of the Pancreas","2025-08-05",{"date":246,"type":247},"2025-08-06","ACTUAL",{"date":249,"type":247},"2024-03-21",{"date":251,"type":239},"2025-12-30",{"name":5,"class":6},17]