[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100503597":3},{"organization":4,"armGroups":7,"interventions":23,"overallOfficials":58,"centralContacts":62,"locations":73,"responsibleParty":97,"collaborators":10,"id":100,"slug":101,"hasResults":102,"nctId":103,"briefTitle":104,"officialTitle":105,"acronym":10,"eligibilityCriteria":106,"healthyVolunteers":107,"sex":108,"minAge":109,"maxAge":110,"enrollmentInfo":111,"targetDuration":10,"studyType":114,"phases":10,"briefSummary":115,"conditions":116,"keywords":119,"overallStatus":75,"whyStopped":10,"lastUpdateSubmitDate":128,"lastUpdatePostDateStruct":129,"startDateStruct":132,"completionDateStruct":134,"leadSponsor":136,"locationsCount":137},{"fullName":5,"class":6},"ART Fertility Clinics LLC","OTHER",[8,18],{"label":9,"type":10,"description":10,"interventionNames":11},"Study Group",null,[12,13,14,15,16,17],"Procedure: ICSI","Procedure: Culture","Genetic: Biopsy","Procedure: Vitrification","Procedure: OPU - Study Group","Procedure: Denudation - Study Group",{"label":19,"type":10,"description":10,"interventionNames":20},"Out of Study Group",[21,22,12,13,14,15],"Procedure: Oocyte Pick Up - Out of Study","Procedure: Denudation - Out of Study",[24,29,33,37,41,46,50,54],{"type":25,"name":26,"description":27,"armGroupLabels":28,"otherNames":10},"PROCEDURE","Oocyte Pick Up - Out of Study","Aspiration of follicles. search for the oocyte(s) All oocytes are grouped in one dish.",[19],{"type":25,"name":30,"description":31,"armGroupLabels":32,"otherNames":10},"Denudation - Out of Study","All oocytes are denuded together. Maturational stages are recorded.",[19],{"type":25,"name":34,"description":35,"armGroupLabels":36,"otherNames":10},"ICSI","One oocyte injected at a time.",[19,9],{"type":25,"name":38,"description":39,"armGroupLabels":40,"otherNames":10},"Culture","One embryo per culture drop. Individual follow-up of the embryo development.",[19,9],{"type":42,"name":43,"description":44,"armGroupLabels":45,"otherNames":10},"GENETIC","Biopsy","One embryo per culture drop.",[19,9],{"type":25,"name":47,"description":48,"armGroupLabels":49,"otherNames":10},"Vitrification","One embryo per vitrification straw.",[19,9],{"type":25,"name":51,"description":52,"armGroupLabels":53,"otherNames":10},"OPU - Study Group","Measure the size of the follicle and aspirate only one follicle and flush. The needle before moving to the second ovary. Oocyte included in the study will be cultured separately (each ovary separately too).",[9],{"type":25,"name":55,"description":56,"armGroupLabels":57,"otherNames":10},"Denudation - Study Group","Oocyte included in the study will be denuded separately. Maturational stages are recorded per follicle.",[9],[59],{"name":60,"affiliation":5,"role":61},"Laura Melado, PhD","PRINCIPAL_INVESTIGATOR",[63,69],{"name":64,"role":65,"phone":66,"phoneExt":67,"email":68},"Barbara Lawrenz, PhD","CONTACT","0097126528000","1108","barbara.lawrenz@artfertilityclinics.com",{"name":70,"role":65,"phone":66,"phoneExt":71,"email":72},"Suzan Samir","1121","suzan.samir@artfertilityclinics.com",[74],{"facility":5,"status":75,"city":76,"state":77,"zip":78,"country":79,"countryCode":80,"cosmosGeoPoint":81,"geoPoint":86,"contacts":87},"RECRUITING","Abu Dhabi","Abu Dhabi Emirate","60202","United Arab Emirates","AE",{"type":82,"coordinates":83},"Point",[84,85],54.39696,24.45118,{"lat":85,"lon":84},[88,89,93,94],{"name":64,"role":65,"phone":66,"phoneExt":67,"email":68},{"name":90,"role":65,"phone":66,"phoneExt":91,"email":92},"Jonalyn Edades","1106","jonalyn.edades@artfertilityclinics.com",{"name":60,"role":61,"phone":10,"phoneExt":10,"email":10},{"name":95,"role":96,"phone":10,"phoneExt":10,"email":10},"Ibrahim ElKhatib","SUB_INVESTIGATOR",{"type":61,"investigatorFullName":98,"investigatorTitle":99,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Laura Melado","Principal Investigator","100503597","is-the-amh-intrafollicular-level-a-predictor-of-the-ploidy-status-of-the-blastocyst-100503597",false,"NCT05837325","Is the AMH Intrafollicular Level a Predictor of the Ploidy Status of the Blastocyst?","Is the AMH Intrafollicular Level a Predictor of the Ploidy Status of the Blastocyst? A Prospective Study","Inclusion Criteria:\n\n* At least one follicle from each ovary at day of trigger\n* Age from 18 to 40 years old\n* Normal menstrual cycle of 25-35 days\n* Poor, normal and high response will be included\n* First follicle punctured from each ovary will be consider for inclusion: if the COC (Cumulus Oocyte Complex) is present in clear FF (Follicular fluid), the FF will be collected separately for further analysis and the oocyte included in the study\n\nExclusion Criteria:\n\n* Very hematic follicular fluid\n* If the COC is not found in the follicular fluid\n* Azoospermia\n* Known chromosomal abnormalities\n* Severe OAT (Oligoasthenoteratozoospermia)",true,"FEMALE","18 Years","40 Years",{"count":112,"type":113},300,"ESTIMATED","OBSERVATIONAL","To investigate, whether on the day of egg retrieval, after ovarian stimulation for ICSI (intracytoplasmic sperm injection), there is a correlation between the intrafollicular AMH (Anti-Müllerian hormone) levels and the ploidy status of the blastocyst.",[117,118],"Infertility, Female","Infertility",[120,121,122,123,124,125,118,126,127],"Estradiol","FSH","LH","AMH","Ploidy","Chromosomes","Progesterone","Inhibin B","2025-09-30",{"date":130,"type":131},"2025-10-02","ACTUAL",{"date":133,"type":131},"2023-05-23",{"date":135,"type":113},"2026-12-31",{"name":5,"class":6},1]