[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100346209":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":33,"locations":42,"responsibleParty":58,"collaborators":25,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":68,"eligibilityCriteria":69,"healthyVolunteers":64,"sex":70,"minAge":71,"maxAge":25,"enrollmentInfo":72,"targetDuration":25,"studyType":75,"phases":76,"briefSummary":78,"conditions":79,"keywords":81,"overallStatus":45,"whyStopped":25,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},{"fullName":5,"class":6},"Rigshospitalet, Denmark","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Ischemic postconditioning","ACTIVE_COMPARATOR","In addition to state of the art primary PCI in patients with TIMI0-1 ischemic postconditioning with an adequately sized balloon (60 reperfusion\u002F60 seconds re-occlusion, four cycles) will be performed, however thrombectomy will not be allowed",[13],"Procedure: Ischemic postconditioning",{"label":15,"type":16,"description":17,"interventionNames":18},"Conventional","PLACEBO_COMPARATOR","State of the art primary PCI in patients with TIMI0-1 will be performed, however thrombectomy will not be allowed",[19],"Procedure: Conventional",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","After 60 seconds of reperfusion, ischemic postconditioning with an adequately sized balloon (60 reperfusion\u002F60 seconds re-occlusion, four cycles) will be performed",[9],null,{"type":22,"name":15,"description":27,"armGroupLabels":28,"otherNames":25},"State of the art primary PCI, however thrombectomy is not allowed",[15],[30],{"name":31,"affiliation":5,"role":32},"Thomas Engstrøm, DMSci","STUDY_CHAIR",[34,38],{"name":31,"role":35,"phone":36,"phoneExt":25,"email":37},"CONTACT","+4535458444","thomas.engstroem@regionh.dk",{"name":39,"role":35,"phone":40,"phoneExt":25,"email":41},"Jacob Lønborg, DMSci","+4535458176","jacob.thomsen.loenborg01@regionh.dk",[43],{"facility":44,"status":45,"city":46,"state":25,"zip":47,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"The Heart Center, Rigshospitalet, University of Copenhagen","RECRUITING","Copenhagen","2100","Denmark","DK",{"type":51,"coordinates":52},"Point",[53,54],12.56553,55.67594,{"lat":54,"lon":53},[57],{"name":31,"role":35,"phone":25,"phoneExt":25,"email":25},{"type":59,"investigatorFullName":60,"investigatorTitle":61,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Thomas Engstrom","Professor","100346209","ischemic-postconditioning-in-stemi-patients-treated-with-primary-pci-100346209",false,"NCT03787745","Ischemic Postconditioning in STEMI Patients Treated With Primary PCI","The Effect of Ischemic Postconditioning in Patients With STEMI Undergoing Primary PCI (DANAMI4-iPOST2)","iPOST2","Inclusion Criteria:\n\n* Age ≥18 years\n* Acute onset of chest pain with \\\u003C 12 hours duration\n* STEMI as characterized by 2 mm ST elevation in 2 or more V1 through V4 leads or presumed new left bundle branch block with minimum of 1 mm concordant ST elevation or 1 mV ST-segment elevation in the limb lead (II, III and aVF, I, aVL) and V4-V6 or ST depression in 2 or more V1 through V4 leads indicating posterior AMI.\n* TIMI flow 0-1 in infarct related artery\n\nExclusion Criteria:\n\n* Potential pregnancy\n* Refusal to participate\n* OHCA without subsequent consciousness despite ROSC\n* Thrombectomy considered unavoidable","ALL","18 Years",{"count":73,"type":74},1800,"ESTIMATED","INTERVENTIONAL",[77],"NA","In a prospective, randomized clinical trial the iPOST2 trial will determine whether ischemic postconditioning reduces reperfusion injury and this will translate into improved clinical outcome of heart failure and death for STEMI patients who present with TIMI0-1 undergoing primary PCI",[80],"ST Segment Elevation Myocardial Infarction",[82,9,83],"Primary PCI","Clinical outcome","2026-03-24",{"date":86,"type":87},"2026-03-30","ACTUAL",{"date":89,"type":87},"2019-02-04",{"date":91,"type":74},"2033-01-31",{"name":5,"class":6},1]