[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100631229":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":34,"locations":39,"responsibleParty":53,"collaborators":25,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":25,"eligibilityCriteria":62,"healthyVolunteers":58,"sex":63,"minAge":64,"maxAge":65,"enrollmentInfo":66,"targetDuration":25,"studyType":69,"phases":70,"briefSummary":72,"conditions":73,"keywords":76,"overallStatus":79,"whyStopped":25,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":89},{"fullName":5,"class":6},"Sun Yat-sen University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Experimental : Ischemic preconditioning","EXPERIMENTAL","One day before the surgery, use a sphygmomanometer to apply pressure to the patient's upper limb to 200mmHg for 5 minutes, then reduce the pressure to 0mmHg for 5 minutes, repeating this process for a total of 3 cycles. On the second day, perform a routine partial nephrectomy",[13],"Procedure: Ischemic preconditioning",{"label":15,"type":16,"description":17,"interventionNames":18},"Comparator : No ischemic preconditioning","ACTIVE_COMPARATOR","Routine partial nephrectomy",[19],"Procedure: NO ischemic preconditioning",[21,26],{"type":22,"name":23,"description":11,"armGroupLabels":24,"otherNames":25},"PROCEDURE","Ischemic preconditioning",[9],null,{"type":22,"name":27,"description":17,"armGroupLabels":28,"otherNames":25},"NO ischemic preconditioning",[15],[30],{"name":31,"affiliation":32,"role":33},"Fangjian Zhou, professor","Sun Yat-sen University Cancer Center (SYSUCC)","PRINCIPAL_INVESTIGATOR",[35],{"name":31,"role":36,"phone":37,"phoneExt":25,"email":38},"CONTACT","020-87343865","zhoufj@sysucc.org.cn",[40],{"facility":41,"status":25,"city":42,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":25},"651 Dongfeng Road East, Yuexiu District, Guangzhou, P.R. China Sun Yat-sen University Cancer Center","Guangzhou","Guangdong","510000","China","CN",{"type":48,"coordinates":49},"Point",[50,51],113.25,23.11667,{"lat":51,"lon":50},{"type":33,"investigatorFullName":54,"investigatorTitle":55,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"ZHOU FANGJIAN","professor","100631229","ischemic-preconditioning-reduces-the-severity-of-acute-kidney-injury-after-partial-nephrectomy-100631229",false,"NCT07497958","Ischemic Preconditioning Reduces the Severity of Acute Kidney Injury After Partial Nephrectomy","Ischemic Preconditioning Reduces the Severity of Acute Kidney Injury After Partial Nephrectomy: a Randomized Controlled Clinical Study","Inclusion Criteria:\n\n* Patients who are scheduled to undergo partial nephrectomy, with no specific surgical procedure limitation, including laparoscopic surgery, robot-assisted surgery, and open surgery\n* Aged 18 to 80\n* Possess good organ function status: sufficient organ function (based on the normal values of the clinical trial center)\n\n  1. Blood routine test: WBC≥3.5×10\\^9\u002FL, absolute neutrophil count ≥1.5×10\\^9\u002FL, PLT≥75.0×10\\^9\u002FL, HGB≥80g\u002FL;\n  2. Liver function: Total bilirubin ≤1.5×upper limit of normal (ULN), aspartate aminotransferase (AST) and alanine aminotransferase (ALT) ≤2.5×ULN;\n\nExclusion Criteria:\n\n* The anesthesiologist assesses that the patient cannot tolerate general anesthesia surgery\n* Individuals with severe cardiovascular and cerebrovascular diseases, uncontrolled hypertension, and diabetes\n* Estimated glomerular filtration rate (eGFR) \\\u003C 30 ml\u002Fmin\u002F1.73m²\n* Horseshoe kidney\n* Solitary kidney\n* Pregnant women","ALL","18 Years","80 Years",{"count":67,"type":68},174,"ESTIMATED","INTERVENTIONAL",[71],"NA","It is demonstrated that remote ischemic preconditioning can alleviate the degree of acute renal injury on the operated side in patients undergoing partial nephrectomy.",[74,75],"Renal Cell Carcinoma (RCC)","Renal Function Abnormal",[75,77,78,23],"Acute kidney injury","Partial nephrectomy","NOT_YET_RECRUITING","2026-03-23",{"date":82,"type":83},"2026-03-27","ACTUAL",{"date":85,"type":68},"2026-04-01",{"date":87,"type":68},"2028-12-31",{"name":5,"class":6},1]