[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100622527":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":11,"centralContacts":35,"locations":11,"responsibleParty":41,"collaborators":11,"id":43,"slug":44,"hasResults":45,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":11,"eligibilityCriteria":49,"healthyVolunteers":50,"sex":51,"minAge":52,"maxAge":53,"enrollmentInfo":54,"targetDuration":11,"studyType":57,"phases":58,"briefSummary":60,"conditions":61,"keywords":64,"overallStatus":79,"whyStopped":11,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":11},{"fullName":5,"class":6},"Gulf Medical University","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"ACL Reconstruction Population","ACTIVE_COMPARATOR",null,[13,14],"Other: High Load Isokinetic Training with Blood Flow Restriction","Other: Low Load Isokinetic Training with Blood Flow Restriction",{"label":16,"type":10,"description":11,"interventionNames":17},"Healthy Population",[13,14],[19,28],{"type":6,"name":20,"description":21,"armGroupLabels":22,"otherNames":23},"High Load Isokinetic Training with Blood Flow Restriction","High Load strength training that was administered through the use of an isokinetic device, and not conventional strength training equipment, combined with blood flow restriction.",[9,16],[24,25,26,27],"High Load strength training","High Load Isokinetic training","Blood Flow Restriction","BFR",{"type":6,"name":29,"description":30,"armGroupLabels":31,"otherNames":32},"Low Load Isokinetic Training with Blood Flow Restriction","Low Load strength training that was administered through the use of an isokinetic device, and not conventional strength training equipment, combined with blood flow restriction.",[9,16],[33,34,26,27],"Low Load strength training","Low Load Isokinetic training",[36],{"name":37,"role":38,"phone":39,"phoneExt":11,"email":40},"Osman Z Khan, Bachelors of Physiotherapy","CONTACT","+971563292389","osman.thekhan@gmail.com",{"type":42,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100622527","isokinetic-exercise-combined-with-blood-flow-restriction-high-load-vs-low-load-training-100622527",false,"NCT07384780","Isokinetic Exercise Combined With Blood Flow Restriction: High-Load Vs Low-Load Training","Isokinetic Exercise Combined With Blood Flow Restriction: High-Load Vs Low-Load Training : A Randomized Controlled Trial in Post-ACL Reconstruction Populations","Inclusion Criteria:\n\nFor ACLR group:\n\n•Isolated unilateral ACL reconstruction 8-16 weeks post-surgery with medical clearance for moderate to high resistance training.\n\nFor control group(healthy population):\n\n* Healthy adults with no musculoskeletal pathology.\n\nExclusion Criteria:\n\n* History of cardiovascular or metabolic diseases\n* Deep vein thrombosis\n* Coagulopathy\n* Hypertension\n* Skin lesions or infections at the site of BFR cuff administration\n* Neuromuscular disorders\n* Non-clearance from the surgeon or physiotherapist or resistance training.",true,"ALL","18 Years","35 Years",{"count":55,"type":56},60,"ESTIMATED","INTERVENTIONAL",[59],"NA","The goal of this clinical trial is to see which type of strengthening exercise with a tight band (blood flow restriction) helps people recover better after ACL reconstruction. The study includes adults after ACL surgery who are doing physiotherapy to rebuild thigh muscle strength and knee function.\n\nThe main questions are:\n\n* Does heavy strengthening with blood flow restriction improve thigh strength, knee function, and daily activities more than light strengthening with blood flow restriction after ACL surgery?\n* Can light strengthening with blood flow restriction give similar benefits to heavy strengthening while putting less strain on the knee?\n\nResearchers will compare a heavy-exercise program plus blood flow restriction to a light-exercise program plus blood flow restriction to see which gives better strength and functional improvements.\n\nParticipants will:\n\n* Come for supervised physiotherapy sessions and do knee exercises on a machine, using either heavy or light loads while a cuff on the thigh gently squeezes to reduce blood flow.\n* Have their leg strength, and knee questionnaires checked several times during the study.",[62,63],"ACL Reconstruction","ACL Repair",[65,66,67,68,62,69,70,71,72,73,74,75,76,77,78],"blood flow restriction training ACL","Blood flow restriction","ACL Rehab","ACLR","BFR therapy anterior cruciate ligament reconstruction","BFR therapy ACLR","BFR Therapy","low-load versus high-load BFR knee rehabilitation","isokinetic strength training after ACL surgery","physiotherapy rehabilitation protocol ACL isokinetic BFR","Knee physiotherapy","ACL","ACL Isokinetic","ACLٍ Isokinetic","NOT_YET_RECRUITING","2026-02-03",{"date":82,"type":83},"2026-02-05","ACTUAL",{"date":85,"type":56},"2026-02",{"date":87,"type":56},"2026-06",{"name":5,"class":6}]