[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100507442":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":29,"centralContacts":33,"locations":43,"responsibleParty":60,"collaborators":28,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":68,"eligibilityCriteria":69,"healthyVolunteers":64,"sex":70,"minAge":71,"maxAge":72,"enrollmentInfo":73,"targetDuration":28,"studyType":76,"phases":77,"briefSummary":79,"conditions":80,"keywords":83,"overallStatus":46,"whyStopped":28,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":99},{"fullName":5,"class":6},"Rennes University Hospital","OTHER",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"3 assessments","EXPERIMENTAL","The randomisation provides for 3 assessments of baseline",[13],"Behavioral: isokinetic strength training of knee extensor and flexor muscles",{"label":15,"type":10,"description":16,"interventionNames":17},"4 assessments","The randomisation provides for 4 assessments of baseline",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"5 assessments","The randomisation provides for 5 assessments of baseline",[13],[23],{"type":24,"name":25,"description":26,"armGroupLabels":27,"otherNames":28},"BEHAVIORAL","isokinetic strength training of knee extensor and flexor muscles","Patients underwent an isokinetic strength training program with 3 sessions per week during five weeks.\n\nProgram consists of excentric contraction of knee flexor and extensor muscles (4 x 7 Contractions at 30°\u002Fs) and concentric contractions at maximal speed where patients can perform 40% of his maximal isometric torque for knee flexor and extensor muscles (2x10 for knee flexors and 2x10 for knee extensors)",[9,15,19],null,[30],{"name":31,"affiliation":5,"role":32},"Sophie HAMEAU, PhD","PRINCIPAL_INVESTIGATOR",[34,39],{"name":31,"role":35,"phone":36,"phoneExt":37,"email":38},"CONTACT","299284218","+33","sophie.hameau@chu-rennes.fr",{"name":40,"role":35,"phone":41,"phoneExt":28,"email":42},"Krsitell COAT","0299282555","kristell.coat@chu-rennes.fr",[44],{"facility":45,"status":46,"city":47,"state":28,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"CHU de Rennes","RECRUITING","Rennes","35033","France","FR",{"type":52,"coordinates":53},"Point",[54,55],-1.67431,48.11109,{"lat":55,"lon":54},[58],{"name":59,"role":35,"phone":28,"phoneExt":28,"email":38},"Sophie HAMEAU",{"type":61,"investigatorFullName":28,"investigatorTitle":28,"investigatorAffiliation":28,"oldNameTitle":28,"oldOrganization":28},"SPONSOR","100507442","isokinetic-strength-training-in-hemiparetic-patient-with-knee-extension-thrust-100507442",false,"NCT05887440","Isokinetic Strength Training in Hemiparetic Patient With Knee Extension Thrust","Effects of Isokinetic Strength Training of Knee Flexor and Extensor Muscles on Walking in Hemiparetic Patients With Knee Extension Thrust","ISOWALK","Inclusion Criteria:\n\n* Hemiparetic patient (hemorragic or ischemic stroke)\n* Subacute stage (\\\u003C 6 Months) ou chronic stage of stroke (\\> 6 months) (6 patients in each group)\n* Age between 18 and 75 years\n* Able to walk 10 meters independently without any assistive devices\n* Knee extension thrust during stance phase of gait cycle (rapid posterior movement of the knee toward extension)\n* Scheduled rehabilitation program with isokinetic strength training\n* affiliation to a social security\n* Patients who received and signed informed consent\n\nExclusion Criteria:\n\n* Major comprehension deficit that not allow to give informed consent and participate to isokinetic strength training (assessed with comprehension subscore of Langague screening Test)\n* non stable (unstable cardiovascular condition)\n* musculoskeletal disorders with knee pain that not allowed isokinetic strength training\n* Botulinum toxin injection less than 3 months or repeated injection in lower limb,\n* Proprioception trouble assessed with proprioception section of the Fugl-Meyer Assessment \\[FMA-P\\] 0\u002F2\n* spasticity of triceps surae ≥2 (Modified Ashworth scale)\n* ankle dorsiflexion angle less than 90°\n* pregnant women or breastfeeding\n* persons with safety measure","ALL","18 Years","75 Years",{"count":74,"type":75},12,"ESTIMATED","INTERVENTIONAL",[78],"NA","The purpose of this study is to assess the impact of an isokinetic strength training of knee flexor and extensor muscles on walking performance in hemiparetic patients with knee extension thrust.",[81,82],"Hemiparesis\u002FHemiplegia (One Sided Weakness\u002FParalysis)","Gait Disorder",[84,85,86,87,88,89],"Stroke","Extensor thrust","resistance training","Isokinetic","walking speed","rehabilitation","2023-09-01",{"date":92,"type":93},"2023-09-05","ACTUAL",{"date":95,"type":93},"2023-08-21",{"date":97,"type":75},"2026-12-01",{"name":5,"class":6},1]