[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100638146":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":37,"centralContacts":41,"locations":47,"responsibleParty":61,"collaborators":63,"id":67,"slug":68,"hasResults":69,"nctId":70,"briefTitle":71,"officialTitle":72,"acronym":30,"eligibilityCriteria":73,"healthyVolunteers":69,"sex":74,"minAge":75,"maxAge":76,"enrollmentInfo":77,"targetDuration":30,"studyType":80,"phases":81,"briefSummary":83,"conditions":84,"keywords":30,"overallStatus":49,"whyStopped":30,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"Nanjing Mingzhou Rehabilitation Hospital","OTHER",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"IT+BFR group","EXPERIMENTAL","Isokinetic Training Combined With Blood Flow Restriction",[13],"Device: Isokinetic Training Combined With Blood Flow Restriction",{"label":15,"type":16,"description":17,"interventionNames":18},"IT group","ACTIVE_COMPARATOR","Isokinetic Training",[19],"Device: Isokinetic Training",{"label":21,"type":16,"description":22,"interventionNames":23},"ACE group","Aerobic Cycling Exercise",[24],"Device: Aerobic Cycling Exercise",[26,31,34],{"type":27,"name":17,"description":28,"armGroupLabels":29,"otherNames":30},"DEVICE","Participants in this group will receive supervised isokinetic muscle strength training targeting the knee musculature using an isokinetic dynamometer. Each session will last 30 minutes throughout the intervention period.",[15],null,{"type":27,"name":11,"description":32,"armGroupLabels":33,"otherNames":30},"Participants in this group will receive isokinetic muscle strength training combined with blood flow restriction (BFR). BFR will be applied to the proximal thigh using a pneumatic cuff at an individualized pressure based on limb occlusion pressure. Isokinetic training will target the knee musculature using an isokinetic dynamometer under supervised conditions. Each session will last 30 minutes, with training performed multiple times per week throughout the intervention period.",[9],{"type":27,"name":22,"description":35,"armGroupLabels":36,"otherNames":30},"Participants in this group will receive supervised aerobic cycling exercise using a stationary bicycle. Training will be performed at a moderate intensity for 30 minutes per session throughout the intervention period.",[21],[38],{"name":39,"affiliation":5,"role":40},"Zhang","PRINCIPAL_INVESTIGATOR",[42],{"name":43,"role":44,"phone":45,"phoneExt":30,"email":46},"Jingzhi Zhang","CONTACT","+86-16677137704","170787717@qq.com",[48],{"facility":5,"status":49,"city":50,"state":30,"zip":30,"country":51,"countryCode":52,"cosmosGeoPoint":53,"geoPoint":58,"contacts":59},"RECRUITING","Nanjing","China","CN",{"type":54,"coordinates":55},"Point",[56,57],118.77778,32.06167,{"lat":57,"lon":56},[60],{"name":43,"role":44,"phone":45,"phoneExt":30,"email":46},{"type":40,"investigatorFullName":43,"investigatorTitle":62,"investigatorAffiliation":5,"oldNameTitle":30,"oldOrganization":30},"Supervisor Technician",[64],{"name":65,"class":66},"Guilin institute of information technology","UNKNOWN","100638146","isokinetic-training-with-blood-flow-restriction-for-patellofemoral-pain-syndrome-100638146",false,"NCT07600827","Isokinetic Training With Blood Flow Restriction for Patellofemoral Pain Syndrome","Effects of Isokinetic Training Combined With Blood Flow Restriction in Patellofemoral Pain Syndrome","Inclusion Criteria:\n\n* Participants aged 18 to 40 years.\n* Clinical diagnosis of patellofemoral pain syndrome (PFPS).\n* Presence of anterior or retropatellar knee pain for at least 3 months.\n* Pain provoked by at least two activities that increase patellofemoral joint load, including squatting, stair climbing, running, jumping, prolonged sitting, or kneeling.\n* Average knee pain intensity of ≥3 on a 10-point visual analog scale (VAS) during aggravating activities.\n* Ability to participate in exercise training and attend scheduled intervention sessions.\n* Willingness to provide written informed consent.\n\nExclusion Criteria:\n\n* History of knee surgery or significant trauma to the lower extremity within the previous 12 months.\n* Clinical evidence of other knee disorders, including ligament injury, meniscal injury, patellar instability, osteoarthritis, or tendinopathy.\n* Presence of neurological, cardiovascular, or systemic musculoskeletal disorders that may affect lower limb function or exercise participation.\n* Current participation in other structured lower extremity rehabilitation or strength training programs.\n* Contraindications to blood flow restriction training, including uncontrolled hypertension, vascular disease, thromboembolic disorders, or clotting abnormalities.\n* Use of pain-relieving injections or surgical interventions for knee pain within the previous 6 months.\n* Pregnancy.\n* Inability to complete the assessment or intervention procedures.","ALL","18 Years","40 Years",{"count":78,"type":79},60,"ESTIMATED","INTERVENTIONAL",[82],"NA","This randomized controlled trial aims to investigate the effects of isokinetic training combined with blood flow restriction (BFR) in individuals with patellofemoral pain syndrome (PFPS).",[85],"Patellofemoral Pain Syndrome","2026-05-15",{"date":88,"type":89},"2026-05-22","ACTUAL",{"date":91,"type":89},"2026-02-25",{"date":93,"type":79},"2026-06",{"name":5,"class":6},1]