[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100613946":3},{"organization":4,"armGroups":7,"interventions":21,"overallOfficials":26,"centralContacts":35,"locations":41,"responsibleParty":63,"collaborators":26,"id":66,"slug":67,"hasResults":68,"nctId":69,"briefTitle":70,"officialTitle":71,"acronym":26,"eligibilityCriteria":72,"healthyVolunteers":68,"sex":73,"minAge":74,"maxAge":75,"enrollmentInfo":76,"targetDuration":26,"studyType":79,"phases":80,"briefSummary":82,"conditions":83,"keywords":85,"overallStatus":44,"whyStopped":26,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"Cairo University","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"isolated muscle facilitation training","EXPERIMENTAL","Participants in this group will receive a standard physical therapy program including range of motion exercise, electrical muscle stimulation, and Mental practice with motor imagery and stretching exercise, isolated muscle facilitation using electromyography (EMG) biofeedback for six weeks, followed by task-oriented training ofthe upper limb for six weeks",[13,14],"Other: standard physical therapy program","Other: isolated muscle facilitation",{"label":16,"type":17,"description":18,"interventionNames":19},"synergistic muscle facilitation training","ACTIVE_COMPARATOR","Participants in this group will receive a standard physical therapy program, including a range of motion exercise, electrical muscle stimulation, Mental practice with motor imagery, and stretching exercise, synergetic muscle facilitation for six weeks, and followed by task-oriented training of the upper limb for six weeks",[13,20],"Other: synergetic muscle facilitation program",[22,27,31],{"type":6,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"standard physical therapy program","* Soft tissue technique (stretch) will be applied for the anterior pectoral region, elbow flexors, pronators, wrist flexors, and finger flexors(for both research groups.\n* Passive Range of motion exercises will be applied for the glenohumeral joint, scapulothoracic articulation, elbow joint, radioulnar joint, and wrist joint(for both research groups).\n* Muscular electrical stimulation will be applied for supraspinatus, anterior and posterior deltoid, biceps and triceps, pronators and supinators, wrist and finger extensors, and finally the lumbricals (Each muscle group 20 min) (for both research groups).\n\nIn mental practice, the patient adheres to a set of imagined task performances ( picking up a cup) or movements (reaching out with the arm).",[9,16],null,{"type":6,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"isolated muscle facilitation","Muscle facilitation exercises will be applied for the anterior deltoid, middle deltoid, posterior deltoid, biceps, triceps, radioulnar pronators and supinators, wrist and finger extensors, wrist and finger flexors, and lumbricals using EMG biofeedback.\n\nDuring EMG biofeedback training, the electrodes will be placed on (pectoralis major, triceps, and finger flexor muscles, and (trapezius, biceps, and wrist flexors) to ensure the isolated firing of each muscle group (100 reps each muscle group). Before training, patients should be instructed how to perform muscle contraction exercises according to the displayed EMG signal through multimedia publicity, to improve their coordination. During training, patients can take a sitting or lying down position. Then, the electrode piece will be attached to the abdominal part of the patients' deltoid muscle, triceps brachii, a forearm muscle group, thus collecting the EMG signal generated by the relaxation of the patients' upper limb muscles",[9],{"type":6,"name":32,"description":33,"armGroupLabels":34,"otherNames":26},"synergetic muscle facilitation program","Muscle facilitation exercises will be applied for the anterior deltoid, middle deltoid, posterior deltoid, biceps, triceps, radioulnar pronators and supinators, wrist and finger extensors, wrist and finger flexors, and lumbricals During the synergetic muscle facilitation, we will permit the muscles that are linked together through flexion or extension synergy to fire together (100 reps each muscle group) using EMG biofeedback training.",[16],[36],{"name":37,"role":38,"phone":39,"phoneExt":26,"email":40},"Mohamed A Mousa, assistant lecturer","CONTACT","+20 10 92841554","Mohamed.Mousa@pt.cu.edu.eg",[42],{"facility":43,"status":44,"city":45,"state":26,"zip":26,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"faculty of Physical Therapy, Cairo University, and El kasr El-Einy hospitals","RECRUITING","Cairo","Egypt","EG",{"type":49,"coordinates":50},"Point",[51,52],31.24967,30.06263,{"lat":52,"lon":51},[55,58,60],{"name":56,"role":57,"phone":26,"phoneExt":26,"email":26},"Abeer Abo-Bakr Elwishy, professor","PRINCIPAL_INVESTIGATOR",{"name":59,"role":57,"phone":26,"phoneExt":26,"email":26},"Ebtesam Mohamed fahmy, professor",{"name":61,"role":62,"phone":26,"phoneExt":26,"email":26},"Shaimaa mohamed Abd Elmageed, assistant professor","SUB_INVESTIGATOR",{"type":57,"investigatorFullName":64,"investigatorTitle":65,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Mohamed Ahmed Mohamed Mousa","Assistant lecturer of physical therapy for neurology and neurosurgery","100613946","isolated-versus-synergetic-muscle-facilitation-on-upper-limb-functional-performance-in-acute-stroke-100613946",false,"NCT07273201","Isolated Versus Synergetic Muscle Facilitation on Upper Limb Functional Performance in Acute Stroke","Effect of Isolated Versus Synergetic Muscle Facilitation on Upper Limb Functional Performance in Patients With Acute Stroke","Inclusion Criteria:\n\n* Unilateral Middle cerebral artery (MCA) stroke patients\n* Brunnstrom stage of recovery 1\\& 2\n* Normal body mass index (18.5 - 24.99 kg\u002Fm2)\n* Dominant handedness\n\nExclusion Criteria:\n\n* Perceptual, apraxia, major cognitive deficits\n* Recurrent stroke\n* Subjects with cerebellar lesions, painful or subluxated shoulder, any contracture or deformity of the upper extremity","ALL","50 Years","60 Years",{"count":77,"type":78},40,"ESTIMATED","INTERVENTIONAL",[81],"NA","This study is a randomized controlled clinical trial that will be carried out to investigate the effect of isolated versus synergetic muscle facilitation on upper limb functional performance in patients with acute stroke.\n\nRESEARCH QUESTION:\n\nIs there a difference between isolated and synergetic muscle facilitation on upper limb functional performance in patients with acute stroke?\n\nIt will be hypothesized that:\n\nThere will be no difference between isolated and synergetic muscle facilitation on upper limb task-oriented training in patients with acute stroke.\n\nTreatment procedures:\n\nStudy group (A): patients will receive a physical therapy program in the form of a range of motion exercise, electrical muscle stimulation, stretching exercise, mental practice with motor imagery, and isolated muscle facilitation using electromyography (EMG) biofeedback for six weeks and followed by task-oriented training of the upper limb for six weeks control group (B): will receive a standard physical therapy program including range of motion exercise, electrical muscle stimulation, Mental practice with motor imagery and stretching exercise, synergetic muscle facilitation for six weeks, and followed by task-oriented training of the upper limb for six weeks.",[84],"Acute Stroke",[86],"acute stroke, upper limb functional performance, muscle facilitation","2025-12-07",{"date":89,"type":90},"2025-12-09","ACTUAL",{"date":92,"type":90},"2025-10-01",{"date":94,"type":78},"2026-07",{"name":5,"class":6},1]