[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100641714":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":18,"centralContacts":25,"locations":31,"responsibleParty":45,"collaborators":49,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":56,"acronym":57,"eligibilityCriteria":58,"healthyVolunteers":59,"sex":60,"minAge":61,"maxAge":18,"enrollmentInfo":62,"targetDuration":18,"studyType":65,"phases":66,"briefSummary":68,"conditions":69,"keywords":73,"overallStatus":74,"whyStopped":18,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"University of Bologna","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Intervention Group","EXPERIMENTAL","4-weeks web-based interventions",[13],"Behavioral: Italian YOLO",{"label":15,"type":16,"description":17,"interventionNames":18},"Waitlist control","NO_INTERVENTION","Participants allocated to the waitlist control group will complete the baseline assessment and the initial post-waitlist assessment before receiving access to the YOLO program. During the waiting period, they will not have access to the intervention content. After completing the post-waitlist assessment, they will be granted full access to the same web-based YOLO ACT program as the experimental group.",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"BEHAVIORAL","Italian YOLO","Participants allocated to the experimental group will receive immediate access to the web-based YOLO program during the initial intervention period. They will be asked to complete one module per week, with each module based on the core principles of ACT. The intervention consists of four online modules designed to promote psychological flexibility.\n\nThe content of the modules will cover the following topics:\n\n1. Values and committed action\n2. Cognitive defusion\n3. Acceptance and willingness\n4. Mindfulness and observer self.",[9],[26],{"name":27,"role":28,"phone":29,"phoneExt":18,"email":30},"Giulia Landi Senior assistant professor, PhD","CONTACT","+39 0547 338535","giulia.landi7@unibo.it",[32],{"facility":5,"status":18,"city":33,"state":18,"zip":18,"country":34,"countryCode":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":42},"Bologna","Italy","IT",{"type":37,"coordinates":38},"Point",[39,40],11.33875,44.49381,{"lat":40,"lon":39},[43],{"name":44,"role":28,"phone":29,"phoneExt":18,"email":30},"Giulia Landi University of Bologna",{"type":46,"investigatorFullName":47,"investigatorTitle":48,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"PRINCIPAL_INVESTIGATOR","Giulia Landi","Senior assistant professor",[50],{"name":51,"class":6},"The University of Queensland","100641714","italian-yolo-a-web-based-act-mental-health-promotion-intervention-for-university-students-100641714",false,"NCT07654569","Italian YOLO: A Web-Based ACT Mental Health Promotion Intervention for University Students","YOLO","Inclusion Criteria:\n\n* University Students\n\nExclusion Criteria:\n\n* Not enrolled in university",true,"ALL","18 Years",{"count":63,"type":64},1000,"ESTIMATED","INTERVENTIONAL",[67],"NA","The mental health of university students requires urgent attention, as many students are exposed to increased risk of psychological distress, including symptoms of depression, anxiety, academic stress, and reduced well-being. Although many students experience mental health difficulties, most do not seek help. University counselling and health services may also face increasing demand and limited resources to meet students' needs.\n\nAcceptance and Commitment Therapy (ACT) is a transdiagnostic psychological approach that aims to increase psychological flexibility. Rather than focusing only on symptom reduction or problem solving, ACT helps individuals develop a more flexible relationship with difficult thoughts and emotions, clarify personally meaningful values, and engage in committed action. However, access to traditional psychological interventions may be limited by long waiting lists, time constraints, conflicts with academic schedules, high costs, stigma, and shortages of trained professionals.\n\nWeb-based interventions may help reduce these barriers by providing accessible and flexible support that students can complete privately and at their own pace. Previous research suggests that ACT can be effectively adapted to online formats and may improve mental health and well-being outcomes in university student populations.\n\nThe present study aims to evaluate the effectiveness of the YOLO web-based ACT intervention among students at the University of Bologna. Participants will be allocated to either immediate access to the YOLO program or a waitlist\u002Fdelayed intervention condition. Outcomes will be assessed at baseline, post-intervention, and follow-up assessments, including psychological flexibility, depression, anxiety, psychological well-being, academic performance, academic self-efficacy, resilience, and purpose in life. The study will examine whether changes in psychological flexibility are consistent with the theoretical basis of the program. It will also assess the feasibility, acceptability, and usability of the intervention to inform its potential dissemination in other Italian higher education contexts. In addition, exploratory analyses will examine caregiving responsibilities among students with caregiving roles and assess whether caregiving demands are associated with mental health, well-being, and academic functioning.",[70,71,72],"Psychological Distress","Psychological Wellbeing","Academic Stress",[22],"NOT_YET_RECRUITING","2026-06-17",{"date":77,"type":78},"2026-06-22","ACTUAL",{"date":80,"type":64},"2026-06-11",{"date":82,"type":64},"2028-12-31",{"name":5,"class":6},1]