[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100580133":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":31,"locations":37,"responsibleParty":50,"collaborators":25,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":25,"eligibilityCriteria":60,"healthyVolunteers":56,"sex":61,"minAge":62,"maxAge":63,"enrollmentInfo":64,"targetDuration":25,"studyType":67,"phases":68,"briefSummary":70,"conditions":71,"keywords":76,"overallStatus":80,"whyStopped":25,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},{"fullName":5,"class":6},"Tanta University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Group I (CVP)","EXPERIMENTAL","patients in this group will receive fluid resuscitation and therapy guided by central venous pressure.",[13],"Procedure: Central venous catheter",{"label":15,"type":10,"description":16,"interventionNames":17},"Group II (IVC)","patients in this group will receive fluid resuscitation and therapy guided by IVC collapsibility index.",[13,18],"Diagnostic Test: IVC collapsibility index",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","Central venous catheter","Central venous catheter will be introduced to measure central venous pressure",[9,15],null,{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":25},"DIAGNOSTIC_TEST","IVC collapsibility index","In supine position, IVC will be assessed in the anteroposterior plane in the subxiphoid view using two-dimensional mode till an optimal view of IVC entering the right atrium will be obtained. Then, measurement of its collapsibility will be done.",[15],[32],{"name":33,"role":34,"phone":35,"phoneExt":25,"email":36},"Sameh Abdelkhalik","CONTACT","01002977048","samehabdelkhalik1982@gmail.com",[38],{"facility":39,"status":25,"city":40,"state":25,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":25},"Tanta University hospitals","Tanta","31511","Egypt","EG",{"type":45,"coordinates":46},"Point",[47,48],31.00192,30.78847,{"lat":48,"lon":47},{"type":51,"investigatorFullName":52,"investigatorTitle":53,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Sameh Abdelkhalik Ahmed Ismaiel","Dr","100580133","ivc-collapsibility-index-or-cvp-as-a-predictor-of-fluid-responsiveness-in-pediatric-sepsis-100580133",false,"NCT06833333","IVC Collapsibility Index or CVP as a Predictor of Fluid Responsiveness in Pediatric Sepsis","Role of Inferior Vena Cava Collapsibility Index or Central Venous Pressure as a Predictor of Fluid Responsiveness in Pediatric Sepsis Due to Perforated Viscus: Prospective Randomized Double-blind Study","Inclusion Criteria:\n\n* Pediatric patients aged 1 to 5 years presented with septic shock due to perforated viscus according to definition of the American College of Critical Care Medicine and International Pediatric Sepsis Consensus.\n\nExclusion Criteria:\n\n* Refusal of the parents to participate in the study\n* Obesity\n* Congenital heart diseases\n* Severe arrythmias\n* Patients developed moderate to severe ARDS\n* Massive ascites\n* Previous abdominal surgery\n* Previous cardiothoracic surgery","ALL","1 Year","5 Years",{"count":65,"type":66},50,"ESTIMATED","INTERVENTIONAL",[69],"NA","Pediatric population who suffered from sepsis due to perforated viscus will receive fluid resuscitation guided by either central venous pressure or guided by IVC collapsibility index.\n\nThe method of guidance of fluid therapy will be applied pre, intra, and postoperatively.\n\nPrimary outcome will be the length of hospital stays, while the secondary outcomes will be the incidence of complications and the length of PICU stays",[72,73,74,75],"Sepsis","Septic Shock","Perforated Viscus","Hospitalism in Children",[77,78,79],"Pediatric","sepsis","Fluid therapy","NOT_YET_RECRUITING","2025-05-02",{"date":83,"type":84},"2025-05-06","ACTUAL",{"date":86,"type":66},"2025-09-15",{"date":88,"type":66},"2025-11-14",{"name":5,"class":6},1]