[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100608836":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":13,"centralContacts":24,"locations":30,"responsibleParty":45,"collaborators":7,"id":48,"slug":49,"hasResults":50,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":7,"eligibilityCriteria":54,"healthyVolunteers":50,"sex":55,"minAge":56,"maxAge":57,"enrollmentInfo":58,"targetDuration":7,"studyType":61,"phases":7,"briefSummary":62,"conditions":63,"keywords":67,"overallStatus":72,"whyStopped":7,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":82},{"fullName":5,"class":6},"Assiut University","OTHER",null,[9],{"type":10,"name":11,"description":12,"armGroupLabels":7,"otherNames":7},"DEVICE","Ultrasound-Guided Inferior Vena Cava Assessment","This intervention involves bedside ultrasound measurement of the inferior vena cava (IVC) diameter and calculation of the IVC collapsibility\u002Fdistensibility index. Assessments will be performed both at initial presentation and after fluid resuscitation in shock patients. The procedure is non-invasive, rapid, and performed according to standardized emergency ultrasound protocols, distinguishing it from invasive monitoring methods.",[14,18,21],{"name":15,"affiliation":16,"role":17},"Alaa M Attia, Professor of Anathesia and ICU","Assit University","PRINCIPAL_INVESTIGATOR",{"name":19,"affiliation":5,"role":20},"Ahmed M Mandor, Consultant of Anathesia ICU","STUDY_DIRECTOR",{"name":22,"affiliation":23,"role":20},"Walaa M Adel, Lecture of emergency medicine","Seuz canal University",[25],{"name":26,"role":27,"phone":28,"phoneExt":7,"email":29},"Mahmoud Ahmed Mohamed Abd Elgwad, M.B.B.Ch","CONTACT","+01280752523","mahmoudataay12@gmail.com",[31],{"facility":32,"status":7,"city":33,"state":34,"zip":7,"country":35,"countryCode":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"Emeregency medicine department ,Assiut University","Asyut","Sahel Selim","Egypt","EG",{"type":38,"coordinates":39},"Point",[40,41],31.18368,27.18096,{"lat":41,"lon":40},[44],{"name":26,"role":27,"phone":28,"phoneExt":7,"email":29},{"type":17,"investigatorFullName":46,"investigatorTitle":47,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"Mahmoud Ahmed Mohamed Abd Elgwad","Principal Investigator at Emergency Medicine department Assiut University","100608836","ivc-ultrasound-versus-central-venous-pressure-for-early-detection-of-hypovolemia-in-shock-patients-100608836",false,"NCT07206732","IVC Ultrasound Versus Central Venous Pressure for Early Detection of Hypovolemia in Shock Patients","Ultrasound-Guided Inferior Vena Cava Assessment Versus Central Venous Pressure Monitoring in Early and Post-Resuscitation Detection of Hypovolemia Among Shocked Patients in the Emergency Department","Inclusion Criteria:\n\n1- Adult patients aged ≥18 years. 2.Both male and female patients will be included in the study. 3. Presentation to the Emergency Department with clinical evidence of shock, defined by: Hypotension (systolic blood pressure \\\u003C90 mmHg or mean arterial pressure \\\u003C65 mmHg).\n\nEvidence of tissue hypoperfusion (e.g., altered mental status, cold extremities, or oliguria).\n\nElevated serum lactate (\\>2 mmol\u002FL). 4. Shock attributed to hypovolemic, septic, or hemorrhagic etiologies. 5. Patients requiring fluid resuscitation and hemodynamic monitoring.\n\nExclusion Criteria:\n\n1 - Patients younger than 18 years. 2. Pregnancy. 3.Cardiogenic or obstructive shock (e.g., cardiac tamponade, massive pulmonary embolism, or tension pneumothorax).\n\n4.Known inferior vena cava (IVC) anomalies (e.g., congenital absence, thrombosis).\n\n5\\. Increased intra-abdominal pressure or severe ascites. 6. Morbid obesity (BMI ≥40 kg\u002Fm²) or any condition interfering with adequate IVC ultrasound visualization.\n\n7\\. Prior central venous catheterization performed before Emergency Department arrival.\n\n8\\. Congestive heart failure (CHF) with left ventricular ejection fraction (LVEF \\\u003C40%) or pulmonary hypertension.\n\n9\\. Refusal of the patient or legal guardian to participate in the study.","ALL","18 Years","65 Years",{"count":59,"type":60},80,"ESTIMATED","OBSERVATIONAL","This study aims to compare ultrasound-guided inferior vena cava (IVC) assessment with central venous pressure (CVP) monitoring for the detection of hypovolemia in shock patients in the emergency department. The primary objective is to evaluate the diagnostic accuracy and clinical utility of IVC collapsibility index compared to CVP values in both early and post-resuscitation phases. The study will prospectively enroll shock patients, collect demographic and clinical data, and analyze the correlation between IVC and CVP measurements to determine their role in guiding fluid resuscitation and hemodynamic management.",[64,65,66],"Shock","Hypovolemia","Circulatory Failure",[64,65,68,69,70,71],"Emergency department","Central venous pressure","Fliud resuscitation","Ultrasound guided IVC","NOT_YET_RECRUITING","2025-11-16",{"date":75,"type":76},"2025-11-19","ACTUAL",{"date":78,"type":60},"2025-12-15",{"date":80,"type":60},"2026-12-15",{"name":5,"class":6},1]