[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100487394":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":28,"centralContacts":35,"locations":41,"responsibleParty":54,"collaborators":56,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":62,"acronym":9,"eligibilityCriteria":63,"healthyVolunteers":60,"sex":64,"minAge":65,"maxAge":66,"enrollmentInfo":67,"targetDuration":9,"studyType":70,"phases":9,"briefSummary":71,"conditions":72,"keywords":9,"overallStatus":74,"whyStopped":9,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"National Heart Centre Singapore","OTHER",[8,14],{"label":5,"type":9,"description":10,"interventionNames":11},null,"At NHCS, patients who have undergone either CTCA or CT CAC scan within past 6 months will be identified. All the consented participants will have a one-off retinal imaging performed at the respective institution by the trained study team member, which should take approximately 15-20 minutes to complete. 3 to 4 questionnaires will also be administered (i.e. EQ5D, International Index of Erectile Function, Pittsburgh Sleep Quality Index, General Questionnaire), depending patient's gender and literacy. Only male patients who are literate in English language will be invited to complete the International Index of Erectile Function questionnaire. Participants have the option to not complete sthe whole IIEF questionnaire or some of the questions if they are not comfortable with answering those questions.",[12,13],"Diagnostic Test: Ocular Imaging","Other: Questionnaires",{"label":15,"type":9,"description":16,"interventionNames":17},"Singapore Eye Research Institute","At SERI, patients who are found to be at high risk for vision threatening diabetic retinopathy will be identified. All the consented participants will have a one-off retinal imaging performed at the respective institution by the trained study team member, which should take approximately 15-20 minutes to complete. 3 to 4 questionnaires will also be administered (i.e. EQ5D, International Index of Erectile Function, Pittsburgh Sleep Quality Index, General Questionnaire), depending patient's gender and literacy. Only male patients who are literate in English language will be invited to complete the International Index of Erectile Function questionnaire. Participants have the option to not complete sthe whole IIEF questionnaire or some of the questions if they are not comfortable with answering those questions.",[12,13],[19,24],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":9},"DIAGNOSTIC_TEST","Ocular Imaging","The retinal photography will be acquired from macula-centre and an optic-disc centre for both left and right eye after their cardiac assessment. Patient will be required to focus at a target inside the machine for approximately 5 to 10 seconds, with a flash followed at the end when eye image is captured. Based on patients' eye conditions, additional or less images may be taken. This allows a snapshot of both retinal and coronary vessels at a single point in time, no mydriatic drops will be used. Participants will be given the option to undergo mydriatic photographs of the retina at SNEC\u002FSERI depending on participant eye condition. For mydriatic photograph, images will be obtained after pupil dilation and graded for presence and severity of diabetic retinopathy according to the modified ETDRS system and other retinal abnormalities by trained graders.",[5,15],{"type":6,"name":25,"description":26,"armGroupLabels":27,"otherNames":9},"Questionnaires","3 to 4 questionnaires will be administered (i.e. EQ5D, International Index of Erectile Function, Pittsburgh Sleep Quality Index, General Questionnaire) to investigate the correlation between clinical characteristics, lifestyle (eg. exercise, sleep, erectile dysfunction) and diet to retinal and coronary vasculature and outcomes.Only male patients who are literate in English language will be invited to complete the International Index of Erectile Function (IIEF) questionnaire. Participants have the option to not complete the whole IIEF questionnaire or some of the questions if they are not comfortable with answering those questions.",[5,15],[29,33],{"name":30,"affiliation":31,"role":32},"Gavin Tan Siew Wei","Singapore National Eye Centre","PRINCIPAL_INVESTIGATOR",{"name":34,"affiliation":5,"role":32},"Weiting Huang",[36],{"name":34,"role":37,"phone":38,"phoneExt":39,"email":40},"CONTACT","9637 0396","6704 8964","huang.weiting@singhealth.com.sg",[42],{"facility":5,"status":9,"city":43,"state":9,"zip":44,"country":43,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"Singapore","169609","SG",{"type":47,"coordinates":48},"Point",[49,50],103.85007,1.28967,{"lat":50,"lon":49},[53],{"name":34,"role":37,"phone":38,"phoneExt":39,"email":40},{"type":55,"investigatorFullName":9,"investigatorTitle":9,"investigatorAffiliation":9,"oldNameTitle":9,"oldOrganization":9},"SPONSOR",[57],{"name":15,"class":6},"100487394","jarvisdhl-screening-tools-100487394",false,"NCT05626517","JARVISDHL Screening Tools","Inclusion Criteria for NHCS:\n\n1. 21 years of age or older\n2. Sufficient language skills in English or Chinese\n3. Provided informed consent\n4. Completed CTCA or CT CAC in the past 6 months.\n\nInclusion Criteria for SERI:\n\n1. 21 years of age or older\n2. Sufficient language skills in English or Chinese\n3. Provided informed consent\n4. Patient diagnosed with Diabetes for more than or equal to 10 years.\n\nExclusion Criteria for NHCS:\n\n1. Patients whose informed consent was not obtained.\n2. Age \\\u003C21 years old\n3. Patients with cardiac event (acute myocardial infarction, Stroke, heart failure, angina requiring hospitalization) and\u002For coronary revascularization (percutaneous coronary intervention (PCI) and\u002For coronary artery bypass grafting (CABG) prior to CTCA\n\nExclusion Criteria in SERI:-\n\n1. Patient whose informed consent was not obtained.\n2. Age \\\u003C21 years old\n3. Patients with cardiac event (acute myocardial infarction, Stroke, heart failure, angina requiring hospitalization) and\u002For coronary revascularization (percutaneous coronary intervention (PCI) and\u002For coronary artery bypass grafting (CABG) prior to CTCA","ALL","21 Years","99 Years",{"count":68,"type":69},2000,"ESTIMATED","OBSERVATIONAL","The main purpose of this study is to pioneer an easy risk stratification tools, which is developed using novel artificial intelligence (AI) algorithms, that will be able to detect common and fatal heart diseases easily simply through a picture of the back of the eye, the retina. The retinal images will be analysed using a computer application with the risk stratification tool to predict health outcome of individual. The study also aims to correlate between clinical characteristics, lifestyle (eg. exercise, sleep, erectile dysfunction) and diet to retinal and coronary vasculature and clinical outcomes.",[73],"Coronary Artery Disease","NOT_YET_RECRUITING","2022-11-22",{"date":77,"type":78},"2022-11-23","ACTUAL",{"date":80,"type":69},"2023-01-30",{"date":82,"type":69},"2027-06-30",{"name":5,"class":6},1]