[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100612024":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":30,"locations":36,"responsibleParty":56,"collaborators":25,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":25,"eligibilityCriteria":66,"healthyVolunteers":62,"sex":67,"minAge":68,"maxAge":25,"enrollmentInfo":69,"targetDuration":25,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":25,"overallStatus":39,"whyStopped":25,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},{"fullName":5,"class":6},"Cairo University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"fentanyl group","ACTIVE_COMPARATOR","fentanyl bolus during induction of anesthesia",[13],"Drug: Fentanyl (IV)",{"label":15,"type":10,"description":16,"interventionNames":17},"lidocaine group","lidocaine bolus during the induction of anesthesia",[18],"Drug: lidocaine",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","Fentanyl (IV)","patients will receive 1 mcg\u002Fkg of Fentanyl (10 mcg\u002FmL).",[9],null,{"type":21,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"lidocaine","patients will receive 1 mg\u002Fkg lidocaine (10mg\u002FmL)",[15],[31],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},"Maha Mostafa","CONTACT","+201000365115","maha.mostafa@cu.edu.eg",[37],{"facility":38,"status":39,"city":40,"state":25,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Kasr Alainy Hospital","RECRUITING","Cairo","11562","Egypt","EG",{"type":45,"coordinates":46},"Point",[47,48],31.24967,30.06263,{"lat":48,"lon":47},[51],{"name":52,"role":33,"phone":53,"phoneExt":54,"email":55},"ahmed hasanin","01095076954","+2","ahmedmohamedhasanin@gmail.com",{"type":57,"investigatorFullName":58,"investigatorTitle":59,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Ahmed Hasanin","professor","100612024","ketamine-lidocaine-versus-ketamine-fentanyl-for-induction-of-anesthesia-in-patients-with-left-ventricular-systolic-dysfunction-undergoing-elective-coronary-artery-bypass-100612024",false,"NCT07248202","Ketamine-lidocaine Versus Ketamine-fentanyl for Induction of Anesthesia in Patients With Left Ventricular Systolic Dysfunction Undergoing Elective Coronary Artery Bypass","A Comparison Between the Effect of Ketamine-lidocaine Versus Ketamine-fentanyl for Induction of Anesthesia on Cerebral Perfusion Guided by Near Infra-red Spectroscopy in Patients With Coronary Artery Disease and Left Ventricular Systolic Dysfunction Undergoing Elective Coronary Artery Bypass Graft Surgery: (A Randomized Controlled Study)","Inclusion Criteria:\n\n* patients with coronary artery disease\n* with moderate to severe left ventricular dysfunction (ejection fraction \\\u003C 40%),\n* scheduled for elective CABG surgery\n\nExclusion Criteria:\n\n* associated chronic stroke, TIA , carotid occlusive disease( due to abnormal vasomotor activity), patients with known neurological impairment (cerebral infarction , dementia ), significant carotid artery stenosis ,\n* valvular heart disease,\n* persistent arrhythmias,\n* congestive cardiac failure,\n* on mechanical ventilation,\n* intra-aortic balloon pump,\n* emergency surgery,\n* and those with known allergy to any of the study's drugs,\n* severe systemic non-cardiac disease and\n* patients with baseline NIRS reading \\\u003C 60%\n* Patients with dementia or visual or auditory impairment","ALL","21 Years",{"count":70,"type":71},40,"ESTIMATED","INTERVENTIONAL",[74],"NA","This study compares ketamine\u002Ffentanyl versus ketamine\u002Flidocaine in term of their impact on cerebral perfusion during CABG. No prior data address these effects, and the goal is to identify the induction regimen that better preserves cerebral oxygenation.",[77,78,79,80,81,82,83],"Coronary Artery Disease (CAD)","Left Ventricular (LV) Systolic Dysfunction","Induction Anesthesia","Coronary Bypass Graft Surgery","Ketamine","Fentanyl","Lidocaine","2026-03-15",{"date":86,"type":87},"2026-03-17","ACTUAL",{"date":89,"type":87},"2025-12-01",{"date":91,"type":71},"2026-07",{"name":5,"class":6},1]