[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100616659":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":26,"locations":30,"responsibleParty":49,"collaborators":26,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":57,"acronym":26,"eligibilityCriteria":58,"healthyVolunteers":55,"sex":59,"minAge":60,"maxAge":26,"enrollmentInfo":61,"targetDuration":26,"studyType":64,"phases":65,"briefSummary":67,"conditions":68,"keywords":70,"overallStatus":72,"whyStopped":26,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":82},{"fullName":5,"class":6},"University of Alabama at Birmingham","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"ketogenic feeding","ACTIVE_COMPARATOR","The ketogenic feeding will have a macronutrient composition of approximately 10% energy from carbohydrates, 25% energy from protein, and 65% energy from fat.",[13],"Behavioral: Ketogenic feeding",{"label":15,"type":16,"description":17,"interventionNames":18},"Standard feeding","PLACEBO_COMPARATOR","The standard, control diet will be compatible with the USDA guidelines. It will consist of approximately 60% carbohydrate, 20% protein, 20% fat. Participants will be given low-fat foods, whole-grain foods, fruits, and vegetables.",[19],"Behavioral: Standard feeding",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"BEHAVIORAL","Ketogenic feeding","The ketogenic feeding will have a macronutrient composition of approximately 10% energy from carbohydrates, 25% energy from protein, and 65% energy from fat. No food group will be excluded in this diet prescription; however, the diet will emphasize low-glycemic sources of carbohydrate, and include mainly whole foods such as non-starchy vegetables with minimal highly processed grain products and added sugar. Protein foods will include meat, poultry, fish, eggs, and whey protein supplements, if necessary. Fat-containing foods will include olive, coconut, and nut oils; butter; tree nuts and nut butters; cheese; cream; coconut milk; avocados; and the fat found in meat. A number of full-fat dairy products will be included. Saturated fat will be limited to 10% of total fat intake. Patients will obtain the majority of their fat intake from poly- and mono-unsaturated fatty acids at a 4:1 ratio.",[9],null,{"type":22,"name":15,"description":28,"armGroupLabels":29,"otherNames":26},"The standard, control diet will be compatible with the USDA guidelines. It will consist of approximately 60% carbohydrate, 20% protein, 20% fat. Participants will be given low-fat foods, whole-grain foods, fruits, and vegetables. The meal plans will minimize cholesterol, high-fat foods, high-cholesterol foods, processed starches, and added sugar, and will provide \\\u003C2300 mg\u002Fday sodium. Saturated fat will be limited to 10% of total fat intake, and all dairy products will be fat-free (or low fat). Participants will obtain the majority of their fat intake from poly- and mono-unsaturated fatty acids at a 4:1 ratio matched to the ketogenic feeding group; however, total grams will be lower.",[15],[31],{"facility":5,"status":26,"city":32,"state":33,"zip":34,"country":35,"countryCode":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"Birmingham","Alabama","35205","United States","US",{"type":38,"coordinates":39},"Point",[40,41],-86.80249,33.52066,{"lat":41,"lon":40},[44],{"name":45,"role":46,"phone":47,"phoneExt":26,"email":48},"Robert Mankowski, PhD","CONTACT","2059963006","rmankowski@uabmc.edu",{"type":50,"investigatorFullName":51,"investigatorTitle":52,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Robert T Mankowski","Associate Professor","100616659","ketogenic-approach-to-restore-muscle-in-older-patients-with-community-acquired-pneumonia---karma-p-trial-100616659",false,"NCT07308483","Ketogenic Approach to Restore Muscle in Older Patients With Community-Acquired Pneumonia - KARMA-P Trial","Inclusion Criteria:\n\n* Age 55 years and older\n* Bacterial community-acquired pneumonia\n* Expected at least 10-day stay in the hospital\n* Ability to ingest food orally\n* Willingness to be randomized to either treatment group\n* Willingness to participate in all study procedures\n\nExclusion Criteria:\n\n* Failure to provide informed consent\n* Moribund\n* Vegetarian\u002Fvegan\n* Severe cardiac disease, including NYHA Class III or IV congestive heart failure, clinically significant aortic stenosis, history of cardiac arrest, use of a cardiac defibrillator, or uncontrolled angina\n* Diagnosed dementia\n* Hip fracture, hip or knee replacement, or spinal surgery within past 4 months\n* Simultaneous participation in another intervention trial","ALL","55 Years",{"count":62,"type":63},30,"ESTIMATED","INTERVENTIONAL",[66],"NA","The purpose of the study is to see if a ketogenic diet compared to a standard diet is better to maintain muscle function and health in hospital admitted pneumonia patients.",[69],"Pneumonia",[9,71],"pneumonia","NOT_YET_RECRUITING","2026-06-22",{"date":75,"type":76},"2026-06-24","ACTUAL",{"date":78,"type":63},"2026-10-01",{"date":80,"type":63},"2029-07-31",{"name":5,"class":6},1]