[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100555685":3},{"organization":4,"armGroups":7,"interventions":27,"overallOfficials":33,"centralContacts":34,"locations":44,"responsibleParty":55,"collaborators":33,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":33,"eligibilityCriteria":65,"healthyVolunteers":61,"sex":66,"minAge":67,"maxAge":68,"enrollmentInfo":69,"targetDuration":33,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":33,"overallStatus":47,"whyStopped":33,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"Addis Ababa University","OTHER",[8,14,18,22],{"label":9,"type":10,"description":11,"interventionNames":12},"Structured nurse-led telephone call reminders plus standard care.","EXPERIMENTAL","Participants in this arm will receive proactive telephone call reminders from nurses for their scheduled follow-up visits. Reminders will be administered initially at 4 months post-recruitment and then every 4 months for a year for HIV-negative women. For women living with HIV, reminders will be administered every 2 months for 6 months after recruitment.",[13],"Behavioral: Intervention 1: Structured nurse-led telephone call reminders. Intervention 2: Home-visit reminders by health extension workers. Intervention 3: Application-based automated SMS text reminders.",{"label":15,"type":10,"description":16,"interventionNames":17},"Home-visit reminders by health extension workers plus standard care.","Health Extension Workers (HEWs) will conduct home visits to remind participants of their scheduled follow-up appointments. Scheduled initially at 4 months post-recruitment for HIV-negative women and 2 months for HIV-positive women, followed by visits every 2 months for 6 months for HIV-positive individuals and every 4 months for 12 months for HIV-negative individuals.",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"Application-based automated SMS text reminders plus standard care.","Participants will receive automated SMS text reminders via a mobile application for their follow-up visits. SMS reminders will be sent initially at 4 months and 2 months post-recruitment for HIV-negative and HIV-positive women, respectively. Subsequent reminders will be sent every 2 months for 6 months for HIV-positive women and every 4 months for 12 months for HIV-negative women.",[13],{"label":23,"type":24,"description":25,"interventionNames":26},"Standard care only","ACTIVE_COMPARATOR","Participants in the control group will receive standard follow-up care according to the guidelines outlined by the Ethiopian Ministry of Health and current clinical practices of the country.These women will be orally informed of their follow-up appointment dates and will receive a post-treatment follow-up card at the baseline. Apart from this information and routine care, no additional interventions will be provided.",[13],[28],{"type":29,"name":30,"description":31,"armGroupLabels":32,"otherNames":33},"BEHAVIORAL","Intervention 1: Structured nurse-led telephone call reminders. Intervention 2: Home-visit reminders by health extension workers. Intervention 3: Application-based automated SMS text reminders.","Information already available",[19,15,23,9],null,[35,40],{"name":36,"role":37,"phone":38,"phoneExt":33,"email":39},"Mr.Alemnew Destaw Mezgebu, MPH","CONTACT","+251979695905","alemrondesta66@gmail.com",{"name":41,"role":37,"phone":42,"phoneExt":33,"email":43},"Dr.Muluken Gizaw Turago, PhD","+251966809345","muluken.gizaw@yahoo.com",[45],{"facility":46,"status":47,"city":48,"state":49,"zip":33,"country":50,"countryCode":51,"cosmosGeoPoint":33,"geoPoint":33,"contacts":52},"Worabe Health Center","RECRUITING","Silte","Southern Ethiopia","Ethiopia","ET",[53],{"name":54,"role":37,"phone":38,"phoneExt":33,"email":39},"Alemnew Destaw Mezgebu, MPH",{"type":56,"investigatorFullName":57,"investigatorTitle":58,"investigatorAffiliation":5,"oldNameTitle":33,"oldOrganization":33},"PRINCIPAL_INVESTIGATOR","Alemnew Destaw Mezgebu","Mr","100555685","key-interventions-to-improve-the-follow-up-adherence-post-cervical-precancerous-lesion-treatment-in-ethiopia-100555685",false,"NCT06515301","Key Interventions to Improve the Follow-up Adherence Post Cervical Precancerous Lesion Treatment in Ethiopia","Key Interventions to Improve the Follow-up Adherence Post Cervical Precancerous Lesion Treatment in Ethiopia: A Pragmatic Randomized Controlled Trial","Inclusion Criteria:\n\n* Women aged 30-49 (HIV-negative).\n* Women over 25 (HIV-positive).\n* Treated for suspicious cervical lesions after a positive VIA screening.\n\nExclusion Criteria:\n\n* History of hysterectomy.\n* Diagnosis of other histological invasive cervical cancer.\n* Suspicious cervical cancer cases.\n* Pregnancy.\n* Prior screening history.\n* Vaginal bleeding.\n* Lack of consent.","FEMALE","25 Years","49 Years",{"count":70,"type":71},466,"ESTIMATED","INTERVENTIONAL",[74],"NA","The goal of this pragmatic randomized control trial is to evaluate the effectiveness of three interventions in improving follow-up adherence among women treated for suspicious cervical lesions in primary healthcare settings in Ethiopia. The interventions include structured nurse-led telephone call reminders, home-visit reminders led by health extension workers, and application-based automated SMS text reminders. The main questions it aims to answer are:\n\n* Does structured nurse-led telephone call reminders improve follow-up adherence among women treated for suspicious cervical lesions compared to standard care?\n* Does home-reminder visits led by a Health Extension Worker (HEW) improve follow-up adherence among women treated for suspicious cervical lesions compared to standard care?\n* Does app-based automated SMS reminders improve follow-up adherence among women treated for suspicious cervical lesions compared to standard care?\n\nStructured Nurse-Led Telephone Call Reminders\n\n* Participants will receive proactive phone call reminders for scheduled follow-up visits.\n* The intervention includes three rounds: initially at 4 months post-recruitment, then every 4 months for HIV-negative women over a year, and every 2 months for 6 months for women living with HIV.\n\nHome-Reminder Visits Led by HEW Health Extension Workers (HEWs) will conduct door-to-door visits to remind participants of their scheduled follow-up appointments.\n\n• Door-to-door Visits will occur initially at 4 months (for HIV-negative women) and 2 months (for HIV-positive women) post-recruitment, then every 2 months for 6 months for HIV-positive and every 4 months for 12 months for HIV-negative participants.\n\nApp-Based Automated SMS Reminders\n\n* Participants will receive SMS-based reminders for their follow-up visits.\n* The intervention consists of three rounds: initial texts at 4 months and 2 months post-recruitment for HIV-negative and HIV-positive women, respectively, followed by reminders every 2 months for 6 months for HIV-positive women and every 4 months for 12 months for HIV-negative women.",[77],"Suspicious Cervical Cancer Lesions Follow up Adherence","2025-06-05",{"date":80,"type":81},"2025-06-10","ACTUAL",{"date":83,"type":81},"2024-11-20",{"date":85,"type":71},"2025-12-30",{"name":5,"class":6},1]