[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100215908":3},{"organization":4,"armGroups":7,"interventions":29,"overallOfficials":47,"centralContacts":51,"locations":59,"responsibleParty":144,"collaborators":10,"id":146,"slug":147,"hasResults":148,"nctId":149,"briefTitle":150,"officialTitle":150,"acronym":10,"eligibilityCriteria":151,"healthyVolunteers":152,"sex":153,"minAge":154,"maxAge":10,"enrollmentInfo":155,"targetDuration":10,"studyType":158,"phases":10,"briefSummary":159,"conditions":160,"keywords":162,"overallStatus":62,"whyStopped":10,"lastUpdateSubmitDate":168,"lastUpdatePostDateStruct":169,"startDateStruct":172,"completionDateStruct":174,"leadSponsor":176,"locationsCount":177},{"fullName":5,"class":6},"Memorial Sloan Kettering Cancer Center","OTHER",[8,18,22,25],{"label":9,"type":10,"description":11,"interventionNames":12},"kidney cancer patients receiving care at MSKCC",null,"Participation will consist of completing the Kidney Cancer Questionnaire Family History Questionnaire and complete the Epidemiologic Questionnaire (when applicable,), and providing a blood sample and saliva sample for germline DNA. In cases where tissue samples from surgically derived tumor specimens are obtained these will used to determine genetic alterations related to cancer predisposition or pathogenicity.",[13,14,15,16,17],"Other: salvia for germline DNA","Behavioral: the Kidney Cancer Questionnaire","Behavioral: Family History Questionnaire (when applicable)","Other: Blood draw","Behavioral: Epidemiologic Questionnaire",{"label":19,"type":10,"description":20,"interventionNames":21},"relatives of patients with kidney cancer","Participation will consist of completing the Kidney Cancer Questionnaire Family History Questionnaire (when applicable,), and providing a saliva sample for germline DNA. In cases where tissue samples from surgically derived tumor specimens are obtained these will used to determine genetic alterations related to cancer predisposition or pathogenicity.",[13,14,15],{"label":23,"type":10,"description":20,"interventionNames":24},"healthy controls who are unrelated & do not have hx of cancer",[13,14,15],{"label":26,"type":10,"description":27,"interventionNames":28},"high risk","Participation will consist of completing the Epidemiologic Questionnaire, Family History Questionnaire (if + FH), provide saliva and blood sample , referral for screening evaluation",[13,15,16,17],[30,33,38,41,44],{"type":6,"name":31,"description":10,"armGroupLabels":32,"otherNames":10},"salvia for germline DNA",[23,26,9,19],{"type":34,"name":35,"description":36,"armGroupLabels":37,"otherNames":10},"BEHAVIORAL","the Kidney Cancer Questionnaire","Patients will complete the appropriate surveys on either paper or on the computer\u002FiPad in the office using REDCap software. If patients are unable to complete their questionnaires at the time of their in-office visit, a link to the questionnaires in REDCap will be emailed to them. The survey data that is collected in REDCap will be stored in REDCap. Clinic staff may also call patients to remind patients to complete questionnaires.",[23,9,19],{"type":34,"name":39,"description":36,"armGroupLabels":40,"otherNames":10},"Family History Questionnaire (when applicable)",[23,26,9,19],{"type":6,"name":42,"description":10,"armGroupLabels":43,"otherNames":10},"Blood draw",[26,9],{"type":34,"name":45,"description":36,"armGroupLabels":46,"otherNames":10},"Epidemiologic Questionnaire",[26,9],[48],{"name":49,"affiliation":5,"role":50},"Jonathan Jonathan, MD","PRINCIPAL_INVESTIGATOR",[52,56],{"name":53,"role":54,"phone":55,"phoneExt":10,"email":10},"Jonathan Coleman, MD","CONTACT","646-422-4432",{"name":57,"role":54,"phone":58,"phoneExt":10,"email":10},"Kenneth Offit, MD","646-888-4050",[60,76,87,98,110,121,133],{"facility":61,"status":62,"city":63,"state":64,"zip":65,"country":66,"countryCode":67,"cosmosGeoPoint":68,"geoPoint":73,"contacts":74},"Memorial Sloan Kettering at Basking Ridge (Consent and Follow-up)","RECRUITING","Basking Ridge","New Jersey","07920","United States","US",{"type":69,"coordinates":70},"Point",[71,72],-74.54932,40.70621,{"lat":72,"lon":71},[75],{"name":53,"role":54,"phone":55,"phoneExt":10,"email":10},{"facility":77,"status":62,"city":78,"state":64,"zip":79,"country":66,"countryCode":67,"cosmosGeoPoint":80,"geoPoint":84,"contacts":85},"Memorial Sloan Kettering Monmouth (Consent and Follow up)","Middletown","07748",{"type":69,"coordinates":81},[82,83],-74.11709,40.39428,{"lat":83,"lon":82},[86],{"name":53,"role":54,"phone":55,"phoneExt":10,"email":10},{"facility":88,"status":62,"city":89,"state":64,"zip":90,"country":66,"countryCode":67,"cosmosGeoPoint":91,"geoPoint":95,"contacts":96},"Memorial Sloan Kettering Bergen (Consent and Follow up )","Montvale","07645",{"type":69,"coordinates":92},[93,94],-74.02292,41.04676,{"lat":94,"lon":93},[97],{"name":53,"role":54,"phone":55,"phoneExt":10,"email":10},{"facility":99,"status":62,"city":100,"state":101,"zip":102,"country":66,"countryCode":67,"cosmosGeoPoint":103,"geoPoint":107,"contacts":108},"Memorial Sloan Kettering Commack (Consent and Follow-up)","Commack","New York","11725",{"type":69,"coordinates":104},[105,106],-73.29289,40.84288,{"lat":106,"lon":105},[109],{"name":53,"role":54,"phone":55,"phoneExt":10,"email":10},{"facility":111,"status":62,"city":112,"state":101,"zip":113,"country":66,"countryCode":67,"cosmosGeoPoint":114,"geoPoint":118,"contacts":119},"Memorial Sloan Kettering Westchester (Consent and Follow up)","Harrison","10604",{"type":69,"coordinates":115},[116,117],-73.71263,40.96899,{"lat":117,"lon":116},[120],{"name":53,"role":54,"phone":55,"phoneExt":10,"email":10},{"facility":122,"status":62,"city":101,"state":101,"zip":123,"country":66,"countryCode":67,"cosmosGeoPoint":124,"geoPoint":128,"contacts":129},"Memorial Sloan Kettering Cancer Center (All Protocol Activities)","10065",{"type":69,"coordinates":125},[126,127],-74.00597,40.71427,{"lat":127,"lon":126},[130,131,132],{"name":53,"role":54,"phone":55,"phoneExt":10,"email":10},{"name":57,"role":54,"phone":58,"phoneExt":10,"email":10},{"name":53,"role":50,"phone":10,"phoneExt":10,"email":10},{"facility":134,"status":62,"city":135,"state":101,"zip":136,"country":66,"countryCode":67,"cosmosGeoPoint":137,"geoPoint":141,"contacts":142},"Memorial Sloan Kettering Nassau (Consent and Follow-Up)","Uniondale","11553",{"type":69,"coordinates":138},[139,140],-73.59291,40.70038,{"lat":140,"lon":139},[143],{"name":53,"role":54,"phone":55,"phoneExt":10,"email":10},{"type":145,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100215908","kidney-cancer-dna-registry-100215908",false,"NCT02087852","Kidney Cancer DNA Registry","Inclusion Criteria:\n\nKidney Cancer Case Cohort:\n\n* Must be ≥ 18 years of age AND\n* Must be an English-speaker AND\n* Must have a diagnosis or suspicion of kidney cancer\n\nFamily Member Cohort:\n\n* Must be ≥ 18 years of age AND\n* Must be an English-speaker AND\n* Must be a blood relative of the proband. Family members of probands including mother, father, sisters, brothers, half-sisters, half-brothers, daughters, sons, grandmothers, grandfathers, as well as aunts and uncles are eligible. These individuals need not have kidney cancer, as they will be used for segregation analysis of suspected variants found in the proband; requesting DNA from relatives is required.\n\nControl Cohort:\n\n* Must be ≥ 18 years of age AND\n* Must be an English-speaker AND\n* Must not have a personal history of cancer, with the exception of nonmelanoma skin cancer, AND\n* Must not be a blood relative of any cases or controls enrolled in this study\n\nExclusion Criteria:\n\n* Patients who, in the opinion of the primary MSKCC clinician or the investigator, have a condition that precludes their ability to provide an informed consent",true,"ALL","18 Years",{"count":156,"type":157},750,"ESTIMATED","OBSERVATIONAL","This registry will help us develop better methods of:\n\n* Preventing these cancers\n* Diagnosing these cancers\n* Treating these cancers",[161],"Renal Cancer",[163,164,165,166,167,26],"Questionnaire","DNA","saliva","kidney cancer","13-218","2026-04-06",{"date":170,"type":171},"2026-04-09","ACTUAL",{"date":173,"type":10},"2014-03",{"date":175,"type":157},"2027-03",{"name":5,"class":6},7]