[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100620938":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":18,"centralContacts":27,"locations":33,"responsibleParty":51,"collaborators":18,"id":55,"slug":56,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":61,"eligibilityCriteria":62,"healthyVolunteers":57,"sex":63,"minAge":64,"maxAge":65,"enrollmentInfo":66,"targetDuration":18,"studyType":69,"phases":70,"briefSummary":72,"conditions":73,"keywords":78,"overallStatus":85,"whyStopped":18,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"University of Gaziantep","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Education and Telephone Counseling Program","EXPERIMENTAL","A nurse-led structured education session covering immunosuppressive medication use, side effects, timing, and self-management strategies. Participants receive an educational booklet and are provided with scheduled telephone counseling sessions designed to reinforce adherence, address patient questions, and support problem-solving. All calls and follow-up interactions are documented. Pre-test, post-test, and follow-up adherence assessments are administered.",[13],"Behavioral: Education and Telephone Counseling Program",{"label":15,"type":16,"description":17,"interventionNames":18},"Standart Care","NO_INTERVENTION","Participants receive standard post-transplant clinical follow-up provided by the hospital, without additional structured education or telephone counseling. Routine care includes medical assessments and medication management per standard transplant center procedures.",null,[20],{"type":21,"name":9,"description":22,"armGroupLabels":23,"otherNames":24},"BEHAVIORAL","A nurse-led structured behavioral intervention designed to improve adherence to immunosuppressive medication. The intervention includes an individualized education session at discharge, provision of an educational booklet, and scheduled telephone counseling at 7-15 days, 4 weeks, and 8 weeks. Participants also receive access to a dedicated phone line for additional support. Counseling focuses on medication routines, problem-solving strategies, reinforcing adherence behaviors, and addressing patient concerns. Pre-test and post-test assessments are used to evaluate changes in knowledge and adherence.",[9],[25,26],"Immunosuppressive Adherence Education","Nurse-Led Tele-Counseling",[28],{"name":29,"role":30,"phone":31,"phoneExt":18,"email":32},"Tugba ALBAYRAM Study Coordinator \u002F Sub-Investigator, Research Assistant Dr.","CONTACT","+905548758383","tugbaalbayram@gmail.com",[34],{"facility":35,"status":18,"city":36,"state":37,"zip":38,"country":39,"countryCode":18,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"Gaziantep University Sahinbey Research and Application Hospital","Gaziantep","Şehitkamil","27310","Turkey (Türkiye)",{"type":41,"coordinates":42},"Point",[43,44],37.3825,37.05944,{"lat":44,"lon":43},[47],{"name":48,"role":30,"phone":49,"phoneExt":18,"email":50},"TUGBA ALBAYRAM","05548758383","tugbaalbayram@hotmail.com",{"type":52,"investigatorFullName":53,"investigatorTitle":54,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"PRINCIPAL_INVESTIGATOR","Tuğba Albayram","Research Assistant Dr","100620938","kidney-transplant-immunosuppressive-therapy-adherence-trial-kite-100620938",false,"NCT07364123","Kidney Transplant Immunosuppressive Therapy Adherence Trial (KITE)","Education and Telephone Counseling to Improve Adherence to Immunosuppressive Medication in Kidney Transplant Recipients: A Randomized Controlled Trial","KITE","Inclusion Criteria:\n\n* Adult kidney transplant recipients aged 18 years or older\n* At least 1 month post-kidney transplantation\n* Able to provide informed consent\n* Cognitively intact and oriented to person, place, and time\n* Able to communicate via telephone\n* Voluntarily willing to participate in the study\n\nExclusion Criteria:\n\n* Under 18 years of age\n* Severe cognitive impairment preventing participation\n* Inability to communicate effectively (hearing or speech limitations without support)\n* Patients who do not meet the post-transplant time threshold (less than 1 month)\n* Patients unwilling or unable to participate in follow-up sessions","ALL","18 Years","70 Years",{"count":67,"type":68},60,"ESTIMATED","INTERVENTIONAL",[71],"NA","This randomized controlled interventional study aims to evaluate the effect of structured education and telephone counseling on immunosuppressive medication adherence among kidney transplant recipients. Poor adherence to immunosuppressive therapy after kidney transplantation is a major risk factor for acute rejection, graft loss, and increased morbidity. Education and behavioral support interventions delivered by nurses may improve medication understanding, adherence behaviors, and self-management skills.\n\nIn this trial, 60 participants will be randomly assigned to either an intervention group receiving individualized education, an immunosuppressive medication adherence booklet, and scheduled telephone counseling sessions, or a control group receiving routine clinical care. Adherence will be assessed using the Immunosuppressive Medication Adherence Scale and biological monitoring through tacrolimus level variability over 8 weeks. Additional outcomes include changes in medication knowledge scores based on pre-test and post-test assessments.\n\nThe study will contribute evidence regarding whether nurse-led telephone counseling and structured education can enhance adherence, improve clinical follow-up, and support long-term graft success in kidney transplant patients.",[74,75,76,77],"Kidney Transplantation","Medication Non-Adherence","Immunosuppressive Therapy","Renal Transplant Recipients",[79,80,81,82,83,84],"Kidney Transplant","Immunosuppressive Medication","Medication Adherence","Telephone Counseling","Patient Education","Tacrolimus Levels","NOT_YET_RECRUITING","2026-01-26",{"date":88,"type":89},"2026-01-28","ACTUAL",{"date":91,"type":68},"2026-01-05",{"date":93,"type":68},"2026-08-15",{"name":5,"class":6},1]