[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100635315":3},{"organization":4,"armGroups":7,"interventions":16,"overallOfficials":10,"centralContacts":22,"locations":10,"responsibleParty":28,"collaborators":10,"id":32,"slug":33,"hasResults":34,"nctId":35,"briefTitle":36,"officialTitle":37,"acronym":10,"eligibilityCriteria":38,"healthyVolunteers":34,"sex":39,"minAge":10,"maxAge":10,"enrollmentInfo":40,"targetDuration":10,"studyType":43,"phases":44,"briefSummary":46,"conditions":47,"keywords":10,"overallStatus":50,"whyStopped":10,"lastUpdateSubmitDate":51,"lastUpdatePostDateStruct":52,"startDateStruct":55,"completionDateStruct":57,"leadSponsor":59,"locationsCount":10},{"fullName":5,"class":6},"Assiut University","OTHER",[8,13],{"label":9,"type":6,"description":10,"interventionNames":11},"group 1 (mechanical alignment)",null,[12],"Procedure: high tibial osteotomy",{"label":14,"type":6,"description":10,"interventionNames":15},"group 2 (kinematic alignment)",[12],[17],{"type":18,"name":19,"description":20,"armGroupLabels":21,"otherNames":10},"PROCEDURE","high tibial osteotomy","High tibial osteotomy (HTO) is a well-established joint-preserving procedure for younger and active patients with medial compartment osteoarthritis associated with varus malalignment. By laterally shifting the mechanical axis of the lower limb, HTO unloads the diseased medial compartment, alleviates pain, and delays the need for knee arthroplasty",[9,14],[23],{"name":24,"role":25,"phone":26,"phoneExt":10,"email":27},"safwat ahmed safwat, resident doctor","CONTACT","+201098444007","safwatahmed46@gmail.com",{"type":29,"investigatorFullName":30,"investigatorTitle":31,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Safwat Ahmed","resident doctor","100635315","kinematic-vs-mechanical-alignment-in-high-tibial-osteotomy-100635315",false,"NCT07551089","Kinematic vs Mechanical Alignment in High Tibial Osteotomy","The Short Term Outcome of Kinematic Versus Mechanichal Alignment After High Tibial Osteotomy for Varus Osteoarthritic Knee : A Prospective Randomized Controlled Trial","Inclusion Criteria:\n\n* Clinical: 1. Age : Adult with symptomatic osteoarthritic varus knee 2-Medial knee pain with functional limitation ≥6 months despite optimized non-operative care.\n\nRadiological: 1- Medial compartment OA in Xray AP-Lateral view 2-Degree of varus ≥3 and ≤15 degree in long film(full-length, standing hip-to-ankle radiographs) 3-•Varus knee (mpta ≤85 degree and ldfa ≤93 and jlca ≤5)\n\nPhysical : 1-Range of motion: Flexion ≥110°, flexion contracture ≤10°, extension lag ≤5°.\n\n2-Gait testing: Able to walk unaided (or with standard aid) for instrumented gait analysis.\n\nExclusion Criteria:\n\n* 1- Predominantly lateral compartment OA 2- severe patellofemoral arthritis 3- Prior high tibial osteotomy, knee arthroplasty, or complex fracture around the knee 4-Inflammatory arthropathies (eg, rheumatoid arthritis) 5- end stage medial compartment osteoarthritis with bone erosions 6-chondrocalcinosis","ALL",{"count":41,"type":42},100,"ESTIMATED","INTERVENTIONAL",[45],"NA","To compare between kinematic and mechanichal alignment after High Tibial Osteotomy (clinically and radiologically)",[48,49],"Osteo Arthritis of the Knee","Genu Varum","NOT_YET_RECRUITING","2026-05-21",{"date":53,"type":54},"2026-05-26","ACTUAL",{"date":56,"type":42},"2026-06-01",{"date":58,"type":42},"2029-10-01",{"name":5,"class":6}]