[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100640681":3},{"organization":4,"armGroups":7,"interventions":35,"overallOfficials":45,"centralContacts":40,"locations":49,"responsibleParty":67,"collaborators":70,"id":74,"slug":75,"hasResults":76,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":40,"eligibilityCriteria":80,"healthyVolunteers":81,"sex":82,"minAge":83,"maxAge":84,"enrollmentInfo":85,"targetDuration":40,"studyType":88,"phases":89,"briefSummary":91,"conditions":92,"keywords":40,"overallStatus":94,"whyStopped":40,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":104},{"fullName":5,"class":6},"Stanford University","OTHER",[8,15,19,23,27,31],{"label":9,"type":10,"description":11,"interventionNames":12},"Biomarker testing (A), Cooling bandana (B), Hand cooling table (C)","EXPERIMENTAL","On day 1 participants use the treadmill for one hour at a research laboratory while being monitored by trained research personnel and no cooling intervention is given to the participants. On day 2, participants use a cooling bandana during exercise for 1 hour. On day 3, participants use a hand cooling table after exercise for 10 minutes during a recovery period.",[13,14],"Other: Hand cooling table","Other: Cooling bandana",{"label":16,"type":10,"description":17,"interventionNames":18},"Biomarker testing (A), Hand cooling table (C), Cooling bandana (B)","On day 1 participants use the treadmill for one hour at a research laboratory while being monitored by trained research personnel and no cooling intervention is given to the participants. On day 2, participants use a hand cooling table after exercise for 10 minutes during a recovery period. On day 3, participants use a cooling bandana during exercise for 1 hour.",[13,14],{"label":20,"type":10,"description":21,"interventionNames":22},"Cooling bandana (B), Biomarker testing (A), Hand cooling table (C)","On day 1, participants use a cooling bandana during exercise for 1 hour at a research laboratory while being monitored by trained research personnel. On day 2 participants use the treadmill for one hour and no cooling intervention is given to the participants. On day 3, participants use a hand cooling table after exercise for 10 minutes during a recovery period.",[13,14],{"label":24,"type":10,"description":25,"interventionNames":26},"Cooling bandana (B), Hand cooling table (C), Biomarker testing (A)","On day 1, participants use a cooling bandana during exercise for 1 hour at a research laboratory while being monitored by trained research personnel. On day 2, participants use a hand cooling table after exercise for 10 minutes during a recovery period. On day 3 participants use the treadmill for one hour and no cooling intervention is given to the participants.",[13,14],{"label":28,"type":10,"description":29,"interventionNames":30},"Hand cooling table (C), Biomarker testing (A), Cooling bandana (B)","On day 1, participants use a hand cooling table after exercise for 10 minutes during a recovery period at a research laboratory while being monitored by trained research personnel. On day 2 participants use the treadmill for one hour and no cooling intervention is given to the participants. On day 3, participants use a cooling bandana during exercise for 1 hour.",[13,14],{"label":32,"type":10,"description":33,"interventionNames":34},"Hand cooling table (C), Cooling bandana (B), Biomarker testing (A)","On day 1, participants use a hand cooling table after exercise for 10 minutes during a recovery period at a research laboratory while being monitored by trained research personnel. On day 2, participants use a cooling bandana during exercise for 1 hour. On day 3 participants use the treadmill for one hour and no cooling intervention is given to the participants.",[13,14],[36,41],{"type":6,"name":37,"description":38,"armGroupLabels":39,"otherNames":40},"Hand cooling table","A participant can rest their hand on the cooling table after the one hour exercise session, and this should cool their body quickly. Cold water is pumped throughout the cooling table.",[9,16,20,24,28,32],null,{"type":6,"name":42,"description":43,"armGroupLabels":44,"otherNames":40},"Cooling bandana","A participant will tie a bandana that has been soaked in cold water onto their forehead. They will wear this bandana during the one hour exercise session.",[9,16,20,24,28,32],[46],{"name":47,"affiliation":5,"role":48},"Julie Parsonnet, MD","PRINCIPAL_INVESTIGATOR",[50],{"facility":5,"status":40,"city":51,"state":52,"zip":53,"country":54,"countryCode":55,"cosmosGeoPoint":56,"geoPoint":61,"contacts":62},"Stanford","California","94305","United States","US",{"type":57,"coordinates":58},"Point",[59,60],-122.16608,37.42411,{"lat":60,"lon":59},[63],{"name":64,"role":65,"phone":40,"phoneExt":40,"email":66},"Astrid Elliott, MS","CONTACT","astride@stanford.edu",{"type":48,"investigatorFullName":68,"investigatorTitle":69,"investigatorAffiliation":5,"oldNameTitle":40,"oldOrganization":40},"Julie Parsonnet","George DeForest Barnett Professor of Medicine, Emerita",[71],{"name":72,"class":73},"National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)","NIH","100640681","laboratory-heat-biomarker-and-cooling-interventions-100640681",false,"NCT07617649","Laboratory Heat Biomarker and Cooling Interventions","Laboratory Based Identification of Heat Stress Biomarkers and Effective Cooling Interventions","Inclusion Criteria:\n\n* Age 18-50\n* Able to communicate in English or Spanish\n* General good health\n* A lifestyle that includes regular patterns of modest exercise\n* Body weight over 80 pounds\n\nExclusion Criteria:\n\n* Cannot provide informed consent\n* Known history of cardiac arrhythmias or having a pacemaker\n* Difficulty swallowing pills\n* Planned upcoming X-ray tests or MRI\n* Known history of gastroparesis, diverticulosis or diverticulitis, or inflammatory bowel disease\n* Previous surgery on stomach or intestines (except for appendix or gallbladder)\n* Pregnancy\n* Self-reported cardiac, kidney, or pulmonary disease, or diabetes\n* Concurrent use of temperature- or inflammation-modulating medications such as steroids or non-steroidal anti-inflammatory drugs (NSAIDs)\n* Staff under the direct supervision of any project directors or employed in the laboratory of the study investigators",true,"ALL","18 Years","50 Years",{"count":86,"type":87},30,"ESTIMATED","INTERVENTIONAL",[90],"NA","Our study has two goals. The first goal is to find a blood test that can detect signs of strain from heat in the body (\"a biomarker\"). Second, the study team wants to identify types of devices that can help people cool down quickly.\n\nBy identifying biomarkers for heat strain, scientists can better track and treat the health effects of heat. The study team will identify such biomarkers by simulating, in a laboratory-based environment, the heat and physical work that real-world workers experience.\n\nIn addition, the study team plans to test two cooling technologies that might keep people cool during physical activity.",[93],"Hyperthermia","NOT_YET_RECRUITING","2026-05-23",{"date":97,"type":98},"2026-06-01","ACTUAL",{"date":100,"type":87},"2026-06",{"date":102,"type":87},"2028-06",{"name":5,"class":6},1]