[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100466103":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":19,"centralContacts":20,"locations":29,"responsibleParty":49,"collaborators":53,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":68,"eligibilityCriteria":69,"healthyVolunteers":64,"sex":70,"minAge":71,"maxAge":19,"enrollmentInfo":72,"targetDuration":19,"studyType":75,"phases":76,"briefSummary":78,"conditions":79,"keywords":19,"overallStatus":31,"whyStopped":19,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"Karolinska University Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"All patients","EXPERIMENTAL","All patients receive the same intervention\u002Fsampling protocol",[13],"Other: Isotopically labeled lactate",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":19},"Isotopically labeled lactate","A bolus dose of isotopically labeled lactate is given and blood samples from existing catheters are drawn",[9],null,[21,26],{"name":22,"role":23,"phone":24,"phoneExt":19,"email":25},"Jonathan Grip, MD, PhD","CONTACT","+46736230906","jonathan.grip@regionstockholm.se",{"name":27,"role":23,"phone":19,"phoneExt":19,"email":28},"Olav Rooyackers, Professor","olav.rooyackers@ki.se",[30],{"facility":5,"status":31,"city":32,"state":33,"zip":34,"country":35,"countryCode":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"RECRUITING","Stockholm","Stockholm County","14186","Sweden","SE",{"type":38,"coordinates":39},"Point",[40,41],18.06871,59.32938,{"lat":41,"lon":40},[44,46],{"name":22,"role":23,"phone":45,"phoneExt":19,"email":25},"+46 73 623 09 06",{"name":47,"role":23,"phone":48,"phoneExt":19,"email":19},"Christian Ahlstedt, MD","+4670 729 3514",{"type":50,"investigatorFullName":51,"investigatorTitle":52,"investigatorAffiliation":5,"oldNameTitle":19,"oldOrganization":19},"PRINCIPAL_INVESTIGATOR","Jonathan Grip","Principal Investigator, PhD",[54,57,59],{"name":55,"class":56},"Region Stockholm","OTHER_GOV",{"name":58,"class":6},"European Society of Intensive Care Medicine",{"name":60,"class":61},"The Scandinavian Society of Anaesthesiology and Intensive Care Medicine (SSAI)","UNKNOWN","100466103","lactate-kinetics-in-septic-shock-100466103",false,"NCT05349370","Lactate Kinetics in Septic Shock","Lactate Kinetics in Patients Treated for Septic Shock","LKISS","Inclusion Criteria:\n\n* Sepsis\n* Age \\>17 years\n* Arterial catheter\n* Lactate \\> 2 mmol at any time point prior to inclusion\n\nExclusion Criteria:\n\n* Mitochondrial defect\n* Degenerative muscle disease\n* Terminal liver failure","ALL","18 Years",{"count":73,"type":74},60,"ESTIMATED","INTERVENTIONAL",[77],"NA","Lactate kinetics will be studied in hospitalized septic patients using a bolus injection of stable isotopically labeled lactate.",[80,81],"Sepsis","Septic Shock","2025-05-20",{"date":84,"type":85},"2025-05-23","ACTUAL",{"date":87,"type":85},"2022-12-28",{"date":89,"type":74},"2026-12-31",{"name":5,"class":6},1]