[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100619339":3},{"organization":4,"armGroups":7,"interventions":23,"overallOfficials":33,"centralContacts":38,"locations":48,"responsibleParty":126,"collaborators":128,"id":132,"slug":133,"hasResults":134,"nctId":135,"briefTitle":136,"officialTitle":137,"acronym":138,"eligibilityCriteria":139,"healthyVolunteers":140,"sex":141,"minAge":142,"maxAge":143,"enrollmentInfo":144,"targetDuration":10,"studyType":147,"phases":10,"briefSummary":148,"conditions":149,"keywords":153,"overallStatus":51,"whyStopped":10,"lastUpdateSubmitDate":157,"lastUpdatePostDateStruct":158,"startDateStruct":161,"completionDateStruct":163,"leadSponsor":165,"locationsCount":166},{"fullName":5,"class":6},"Lille Catholic University","OTHER",[8,15,19],{"label":9,"type":10,"description":11,"interventionNames":12},"General Population Group",null,"Patients aged between 18 and 75 years old who did not take part in the TOPATA study in 2021 and who visit their general practitioner for a consultation (for whatever reason)",[13,14],"Other: Epidemiological study","Diagnostic Test: Blood and urine tests",{"label":16,"type":10,"description":17,"interventionNames":18},"Gout Group","Patients aged between 18 and 75 years old who are treated at the rheumatology clinic of the Taaone Hospital Centre (CHT) in Papeete by Dr Baptiste Gérard.\n\n* There is a tophaceous gout subgroup: patients with tophaceous gout.\n* And a gout attack subgroup: patients presenting with a gout crisis.",[13,14],{"label":20,"type":10,"description":21,"interventionNames":22},"Follow-up group 2021","Patients aged between 18 and 75 years old who were included in the TOPATA study in 2021 and for whom genetic and biological samples during the 2021 study were taken.\n\nPatients must have had hyperuricaemia without signs of gout OR without hyperuricaemia or gout at the time of inclusion in the 2021 TOPATA study.",[13,14],[24,28],{"type":6,"name":25,"description":26,"armGroupLabels":27,"otherNames":10},"Epidemiological study","Collection of sociodemographic data, collection of treatment data, standard and clinical ophthalmological examination, physical and biological measurements, clinical characteristics specific to chronic and metabolic diseases, questionnaires (gout questionnaire, health assessment questionnaire (HAQ-II), EuroQol (EQ)-5D-5L, joint pain, state of health, diet and physical activity, access to care, addictions, sleep quality, pain scale (EVA), personal and family history) will be performed.",[20,9,16],{"type":29,"name":30,"description":31,"armGroupLabels":32,"otherNames":10},"DIAGNOSTIC_TEST","Blood and urine tests","Collection of blood and urine samples for genetic, biochemical, omics, and biobank analyses, in order to characterize cardiometabolic health markers will be performed.",[20,9,16],[34],{"name":35,"affiliation":36,"role":37},"Tristan Pascart, Professor","GHICL","PRINCIPAL_INVESTIGATOR",[39,44],{"name":40,"role":41,"phone":42,"phoneExt":10,"email":43},"Marie De Solere","CONTACT","+33 3 20 22 59 31","desolere.marie@ghicl.net",{"name":45,"role":41,"phone":46,"phoneExt":10,"email":47},"Berenice Marchant","+33 3 20 22 57 51","marchant.berenice@ghicl.net",[49,66,80,91,106,116],{"facility":50,"status":51,"city":52,"state":10,"zip":53,"country":54,"countryCode":10,"cosmosGeoPoint":55,"geoPoint":60,"contacts":61},"Medical Office Dr Antoine Scuiller","RECRUITING","Faa'a","98702","French Polynesia",{"type":56,"coordinates":57},"Point",[58,59],-149.59963,-17.55329,{"lat":59,"lon":58},[62],{"name":63,"role":41,"phone":64,"phoneExt":10,"email":65},"Antoine Scuiller","+689 87 29 99 11","taoteantoine@gmail.com",{"facility":67,"status":51,"city":68,"state":10,"zip":69,"country":54,"countryCode":10,"cosmosGeoPoint":70,"geoPoint":74,"contacts":75},"Medical Office Dr Cedric Gueguen","Papeete","98713",{"type":56,"coordinates":71},[72,73],-149.56843,-17.5347,{"lat":73,"lon":72},[76],{"name":77,"role":41,"phone":78,"phoneExt":10,"email":79},"Cedric Gueguen","+689 89 51 10 50","Docteur.cedricgueguen@gmail.com",{"facility":81,"status":51,"city":68,"state":10,"zip":82,"country":54,"countryCode":10,"cosmosGeoPoint":83,"geoPoint":85,"contacts":86},"Medical Office Dr Voradeth Nouanesengsy","98714",{"type":56,"coordinates":84},[72,73],{"lat":73,"lon":72},[87],{"name":88,"role":41,"phone":89,"phoneExt":10,"email":90},"Voradeth Nouanesengsy","+689 89 52 59 17","taotevoradeth@gmail.com",{"facility":92,"status":93,"city":94,"state":10,"zip":95,"country":54,"countryCode":10,"cosmosGeoPoint":96,"geoPoint":100,"contacts":101},"CH de Polynesie Française Papeete","NOT_YET_RECRUITING","Pirae","98716",{"type":56,"coordinates":97},[98,99],-149.55119,-17.52985,{"lat":99,"lon":98},[102],{"name":103,"role":41,"phone":104,"phoneExt":10,"email":105},"Baptiste Gerard","+689 40 48 62 62","bap.gerard@gmail.com",{"facility":107,"status":51,"city":94,"state":10,"zip":95,"country":54,"countryCode":10,"cosmosGeoPoint":108,"geoPoint":110,"contacts":111},"Medical Office Dr Nanethida Nouanesengsy",{"type":56,"coordinates":109},[98,99],{"lat":99,"lon":98},[112],{"name":113,"role":41,"phone":114,"phoneExt":10,"email":115},"Nanethida Nouanesengsy","+689 87 23 67 12","docteurnane@gmail.com",{"facility":117,"status":51,"city":94,"state":10,"zip":95,"country":54,"countryCode":10,"cosmosGeoPoint":118,"geoPoint":120,"contacts":121},"Medical Office Dr Raphael Habib",{"type":56,"coordinates":119},[98,99],{"lat":99,"lon":98},[122],{"name":123,"role":41,"phone":124,"phoneExt":10,"email":125},"Raphael Habib","+689 40 85 13 23","raphaelhabib@hotmail.fr",{"type":127,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[129],{"name":130,"class":131},"Variant Bio, Inc.","INDUSTRY","100619339","landscape-of-gout-in-french-polynesia-100619339",false,"NCT07343336","Landscape of Gout in French Polynesia.","FENUA-METABOGOUT : Genetic Landscape of Gout, Inflammation and Metabolic Diseases in French Polynesia.","METABOGOUT","Inclusion Criteria:\n\nAll participants:\n\n* Age between 18 and 75 years old inclusive\n* Signature of informed consent\n* Fasting for the collection of biological samples\n* Declared Polynesian ancestry\n* Affiliated to a social security scheme\n\nGeneral population group :\n\n* Not having participated to the 2021 TOPATA study\n* Visiting a general practitioner (for whatever reason)\n\nGout Group :\n\n* Managed at the rheumatology clinic of the Taaone Hospital Centre (CHT) in Papeete by Dr Baptiste Gérard.\n\nTophaceous gout sub-group:\n\n* Present with tophaceous gout.\n\nGout crisis subgroup:\n\n* Be within 48 hours of the onset of a gout attack\n* Agree to return 1 week after inclusion for the second blood and urine sample.\n\n  2021 follow-up group:\n* To have been included in the TOPATA study in 2021\n* Have taken the genetic and biological samples that generated the genetic and serum urate data for the 2021 study\n* Have hyperuricaemia without signs of gout OR without hyperuricaemia or gout at the time of inclusion in TOPATA\n\nExclusion Criteria:\n\nAll participants :\n\n* Refusal or inability to understand or give consent\n* Physical inability to follow and respect the protocol\n* 1st degree relative\\*,\n* Person under guardianship or trusteeship\n* Pregnant or breast-feeding woman\n\n  \\* If several relatives from the same household are eligible to participate, only one person may be included in the study. The choice is left to the discretion of the investigator or the first person met. However, both members of a couple (e.g. husband and wife) may participate.\n* General population group :\n* Unable to return for sampling if required.\n* Gout group :\n* Person wearing a knee prosthesis\n* People suffering from other inflammatory rheumatic diseases",true,"ALL","18 Years","75 Years",{"count":145,"type":146},2750,"ESTIMATED","OBSERVATIONAL","The aim of this research is to characterise the genetic and molecular landscape of gout, inflammation and metabolic diseases, as well as the associated molecular, anthropomorphic and pathological characteristics.",[150,151,152],"Gout Disease","Metabolic Diseases","Inflammation",[154,155,156],"Gout disease","metabolic disease","inflammation","2026-01-06",{"date":159,"type":160},"2026-01-15","ACTUAL",{"date":162,"type":160},"2025-09-02",{"date":164,"type":146},"2027-09",{"name":5,"class":6},6]