[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100434273":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":34,"locations":42,"responsibleParty":59,"collaborators":63,"id":77,"slug":78,"hasResults":79,"nctId":80,"briefTitle":81,"officialTitle":82,"acronym":83,"eligibilityCriteria":84,"healthyVolunteers":79,"sex":85,"minAge":86,"maxAge":87,"enrollmentInfo":88,"targetDuration":25,"studyType":91,"phases":92,"briefSummary":94,"conditions":95,"keywords":97,"overallStatus":44,"whyStopped":25,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":101,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":108,"locationsCount":109},{"fullName":5,"class":6},"Obstetrics & Gynecology Hospital of Fudan University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"1","EXPERIMENTAL","the group of LRH",[13],"Other: Total Laparoscopic or Robotic Radical Hysterectomy",{"label":15,"type":16,"description":17,"interventionNames":18},"2","ACTIVE_COMPARATOR","the group of ARH",[19],"Other: Total Abdominal Radical Hysterectomy",[21,26],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"Total Laparoscopic or Robotic Radical Hysterectomy","Stage IA1 with lymphovascular interstitial infiltration and IA2 surgical approach was type B (modified radical hysterectomy plus bilateral pelvic lymph node dissection, i.e., resection of 1\\~2 cm of the parametrium and 1\\~2 cm of the vagina) with abdominal para-aortic lymph node dissection if necessary (surgical staging according to FIGO 2018 and surgical staging according to Querleu-Morrow staging).",[9],null,{"type":6,"name":27,"description":23,"armGroupLabels":28,"otherNames":25},"Total Abdominal Radical Hysterectomy",[15],[30],{"name":31,"affiliation":32,"role":33},"Hua Jiang, PHD","The Obstetrics and Gynecology Hospital of Fudan University","PRINCIPAL_INVESTIGATOR",[35,39],{"name":31,"role":36,"phone":37,"phoneExt":25,"email":38},"CONTACT","(021)33189900-6529","jianghua@fudan.edu.cn",{"name":40,"role":36,"phone":37,"phoneExt":25,"email":41},"Xin Wu, PHD","wuxin_fc@fudan.edu.cn",[43],{"facility":32,"status":44,"city":45,"state":25,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"RECRUITING","Shanghai","20000","China","CN",{"type":50,"coordinates":51},"Point",[52,53],121.45806,31.22222,{"lat":53,"lon":52},[56,57],{"name":31,"role":36,"phone":25,"phoneExt":25,"email":25},{"name":25,"role":36,"phone":58,"phoneExt":25,"email":38},"(86)13601978182",{"type":60,"investigatorFullName":61,"investigatorTitle":62,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"SPONSOR_INVESTIGATOR","Hua Jiang","Chief Physician",[64,66,68,70,72,75],{"name":65,"class":6},"Children's Hospital of Fudan University",{"name":67,"class":6},"Xinhua Hospital, Shanghai Jiao Tong University School of Medicine",{"name":69,"class":6},"Shanghai Zhongshan Hospital",{"name":71,"class":6},"RenJi Hospital",{"name":73,"class":74},"Taizhou Hospital, Affiliated Cancer Hospital of the University of Chinese Academy of Sciences","UNKNOWN",{"name":76,"class":6},"First Affiliated Hospital of Wenzhou Medical University","100434273","laparoscopic-or-abdominal-radical-hysterectomy-for-cervical-cancerstage-ia1-with-lvsi-ia2-100434273",false,"NCT04934982","Laparoscopic or Abdominal Radical Hysterectomy for Cervical Cancer(Stage IA1 With LVSI, IA2)","A Multicenter Noninferior Randomized Controlled Study Comparing the Efficacy of Laparoscopic Versus Abdominal Radical Hysterectomy for Cervical Cancer (Stage IA1 With LVSI, IA2)","LAUNCH 1","Inclusion Criteria:\n\n1. Clinical diagnosis of squamous carcinoma of the cervix, adenocarcinoma, squamous adenocarcinoma (IA1 with lymphovascular interstitial invasion, stage IA2).\n2. Age ≥ 21 years and ≤ 70 years.\n3. Surgery type B and C (refer to Q-M surgical staging)\n4. Normal range of liver and kidney function and blood count (specific details below) Hemoglobin \\> 60g\u002FL Platelets \\> 70\\*109\u002FL Leukocytes \\> 3\\*109\u002FL Creatinine \\\u003C 50mg\u002FdL Transaminase abnormal indicators ≤ 3 Maximum value of transaminases not exceeding 3 times the corresponding normal value.\n5. No history of other malignancies.\n6. Non-pregnancy.\n7. Physical strength classification: Karnofsky score ≥ 60;\n8. Subjects voluntarily joined the study, signed the informed consent form, were compliant and cooperated with the follow-up.\n9. No psychiatric disorders and other serious immune system disorders (e.g. lupus erythematosus, myasthenia gravis, HIV infection, etc.) (Note: Maximum diameter measurement of cervical lesions is based on PET-CT, or CT, or MRI)\n\nExclusion Criteria:\n\n1. Those who are contraindicated for various surgeries and cannot undergo surgery.\n2. Patients who have received pelvic\u002Fabdominal radiotherapy irradiation or neoadjuvant chemotherapy for cervical cancer.\n3. Patients with recurrent cervical cancer\n4. Patients with CT, MRI or PET-CT suggesting suspicious metastasis of pelvic lymph nodes with maximum diameter \\>2cm after further improvement of preoperative examination.","FEMALE","21 Years","70 Years",{"count":89,"type":90},690,"ESTIMATED","INTERVENTIONAL",[93],"NA","The purpose of this study is to confirm whether there is a difference between laparoscopic radical hysterectomy (LRH) and abdominal radical hysterectomy (ARH) in patient survival for Cervical Cancer (Stage IA1 with LVSI, IA2)",[96],"Cervical Cancer",[96,98,99],"Abdominal Radical Hysterectomy","Laparoscopic Radical Hysterectomy","2021-11-02",{"date":102,"type":103},"2021-11-10","ACTUAL",{"date":105,"type":103},"2021-09-24",{"date":107,"type":90},"2026-06",{"name":61,"class":6},1]