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Vaudois","ACTIVE_NOT_RECRUITING","Lausanne","1011",{"type":55,"coordinates":224},[225,226],6.63282,46.516,{"lat":226,"lon":225},{"type":229,"investigatorFullName":230,"investigatorTitle":231,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"SPONSOR_INVESTIGATOR","Thomas Riva","Prof. Dr. med.",[233,235,237,239,241,243,245,247,249,250],{"name":234,"class":6},"University Hospital, Geneva",{"name":236,"class":6},"Kantonsspital Aarau",{"name":238,"class":6},"Centre Hospitalier Universitaire Vaudois",{"name":240,"class":6},"Charite University, Berlin, Germany",{"name":69,"class":242},"UNKNOWN",{"name":244,"class":6},"The Hospital for Sick Children",{"name":246,"class":6},"Istituto Giannina Gaslini",{"name":248,"class":242},"Cantonal Hospital of Lucerne",{"name":47,"class":6},{"name":251,"class":6},"Montreal Children's Hospital of the MUHC","100513594","laryngoscopy-for-neonatal-and-infant-airway-management-with-supplemental-oxygen-at-different-flow-rates-optimise-2-100513594",false,"NCT05967507","Laryngoscopy for Neonatal and Infant Airway Management wIth Supplemental Oxygen at Different Flow Rates (OPTIMISE-2)","Laryngoscopy for Neonatal and Infant Airway Management wIth Supplemental Oxygen at Different Flow Rates (OPTIMISE-2): a Multi-center, Non-inferiority, Prospective Randomized Controlled Trial","OPTIMISE-2","Inclusion Criteria:\n\n* Pediatric patients requiring oral or nasal tracheal intubation for elective, semi-elective, or urgent surgical and non-surgical indications.\n* Neonates and infants up to 52 weeks postconceptual age, with legal guardians providing written informed consent before the intervention\n\nExclusion Criteria:\n\n* Prediction of difficult intubation upon physical examination or previous history of difficult intubation, mandating a technique different than direct laryngoscopy to secure the airway;\n* Congenital heart disease demanding FiO2 \\\u003C 1.0\n* Cardiopulmonary collapse requiring advanced life support\n* Intubation for emergency surgical and non-surgical indications.","ALL","52 Weeks",{"count":263,"type":264},1192,"ESTIMATED","INTERVENTIONAL",[267],"NA","This study aims to investigate the optimal oxygen flow rate needed during tracheal intubation with the C-MAC video laryngoscope (Karl Storz, Tuttlingen, Germany) using Miller-blade or Macintosh-blade size No. 0 or No. 1 in the operating room or intensive care unit. The investigators hypothesize that the difference between low-flow and high-flow supplemental oxygen is negligible.",[270],"Airway Management","2026-05-09",{"date":273,"type":274},"2026-05-12","ACTUAL",{"date":276,"type":274},"2023-12-01",{"date":278,"type":264},"2027-09",{"name":230,"class":6},11]