[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100439934":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":25,"locations":36,"responsibleParty":59,"collaborators":10,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":10,"eligibilityCriteria":68,"healthyVolunteers":64,"sex":69,"minAge":10,"maxAge":10,"enrollmentInfo":70,"targetDuration":73,"studyType":74,"phases":10,"briefSummary":75,"conditions":76,"keywords":79,"overallStatus":38,"whyStopped":10,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},{"fullName":5,"class":6},"Seattle Children's Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Patients presenting with TTTS",null,"Pregnant persons between 16 and 36 weeks of pregnancy with a diagnosis of twin to twin transfusion syndrome",[13],"Procedure: Fetoscopic laser ablation",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"PROCEDURE","Fetoscopic laser ablation","Under ultrasound guidance, a 2 mm skin incision will be made and a 10Fr Cook Check Flow valve cannula and trocar will be introduced into the amniotic cavity.\n\nThe communicating vessels will be located endoscopically using a Storz straight or curved semirigid fetoscopes in a fetoscopic sheath, a Humanitarian Use Device, used with permission of the Federal Drug Administration under a Humanitarian Device Exemption agreement with Karl Storz, Inc, and will be ablated with a diode laser fiber that is passed through the operating channel of the endoscope.",[9],[21],{"name":22,"affiliation":23,"role":24},"Martin P Walker, MD","Seattle Childrens Hospital","PRINCIPAL_INVESTIGATOR",[26,31],{"name":22,"role":27,"phone":28,"phoneExt":29,"email":30},"CONTACT","206-987-3539","73539","martin.walker@seattlechildrens.org",{"name":32,"role":27,"phone":33,"phoneExt":34,"email":35},"Melissa Dorn, RN MN","206-987-4137","74137","melissa.dorn@seattlechildrens.org",[37,52],{"facility":23,"status":38,"city":39,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"RECRUITING","Seattle","Washington","98015","United States","US",{"type":45,"coordinates":46},"Point",[47,48],-122.33207,47.60621,{"lat":48,"lon":47},[51],{"name":22,"role":27,"phone":28,"phoneExt":29,"email":30},{"facility":53,"status":54,"city":39,"state":40,"zip":55,"country":42,"countryCode":43,"cosmosGeoPoint":56,"geoPoint":58,"contacts":10},"University of Washington","ACTIVE_NOT_RECRUITING","98195",{"type":45,"coordinates":57},[47,48],{"lat":48,"lon":47},{"type":24,"investigatorFullName":60,"investigatorTitle":61,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Martin Walker","Co-Director Seattle Childrens Fetal Intervention and Surgery Program, Clinical Assistant Professor","100439934","laser-photocoagulation-of-communicating-vessels-in-twin-to-twin-transfusion-syndrome-100439934",false,"NCT05008744","Laser Photocoagulation of Communicating Vessels in Twin-to-Twin Transfusion Syndrome","Laser Photocoagulation of Communicating Vessels in Twin-to-Twin Transfusion Syndrome (TTTS)","Inclusion Criteria:\n\n* Single placenta (Monochorionic)\n* Polyhydramnios present in recipient twin (Greater than 8 cm maximum vertical pocket below 20 weeks and greater than a 10 cm pocket for greater than 20 weeks gestational age)\n* Oligohydramnios present in donor twin (Less than 2 cm maximum vertical pocket)\n* Prominent bladder in the recipient\u002F non-filling bladder in the donor\n* Thin dividing membrane\n\nExclusion Criteria:\n\n* Patients unwilling to participate in the study or to be followed up\n* Presence of major congenital anomalies incompatible with survival\n* Active pre-term labor Ruptured membranes\n* Chorioamnionitis\n* Vaginal bleeding","FEMALE",{"count":71,"type":72},2000,"ESTIMATED","9 Months","OBSERVATIONAL","The purpose of this study is to evaluate the use of diode laser photocoagulation of the communicating vessels in twin-to- twin transfusion syndrome (TTTS) with respect to maternal, fetal and neonatal outcomes.",[77,78],"Twin to Twin Transfusion as Antepartum Condition","Monochorionic Diamniotic Placenta",[80,81,82,83],"Twin","Monochorionic","Fetoscopy","Laser","2024-04-18",{"date":86,"type":87},"2024-04-19","ACTUAL",{"date":89,"type":87},"2021-10-01",{"date":91,"type":72},"2031-10-01",{"name":5,"class":6},2]