[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100545987":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":22,"centralContacts":27,"locations":33,"responsibleParty":50,"collaborators":11,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":11,"eligibilityCriteria":58,"healthyVolunteers":59,"sex":60,"minAge":61,"maxAge":11,"enrollmentInfo":62,"targetDuration":11,"studyType":65,"phases":66,"briefSummary":68,"conditions":69,"keywords":11,"overallStatus":35,"whyStopped":11,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":80},{"fullName":5,"class":6},"Sciton","INDUSTRY",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Treatment + PRP Arm","ACTIVE_COMPARATOR",null,[13],"Device: Fractional 2940 nm Laser",{"label":15,"type":10,"description":11,"interventionNames":16},"Treatment only Arm",[13],[18],{"type":19,"name":20,"description":20,"armGroupLabels":21,"otherNames":11},"DEVICE","Fractional 2940 nm Laser",[9,15],[23],{"name":24,"affiliation":25,"role":26},"Josee Parent, MD","Clinique Medicale Uro-Gyneco de l'Abitibi","PRINCIPAL_INVESTIGATOR",[28],{"name":29,"role":30,"phone":31,"phoneExt":11,"email":32},"J Patel","CONTACT","6504939155","clinicaltrials@sciton.com",[34],{"facility":25,"status":35,"city":36,"state":37,"zip":38,"country":39,"countryCode":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"RECRUITING","Val-d'Or","Quebec","J9P1W1","Canada","CA",{"type":42,"coordinates":43},"Point",[44,45],-77.79737,48.0974,{"lat":45,"lon":44},[48],{"name":24,"role":30,"phone":49,"phoneExt":11,"email":11},"819-825-3800",{"type":51,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100545987","laser-treatment-for-lichen-sclerosus-100545987",false,"NCT06389071","Laser Treatment for Lichen Sclerosus","Safety and Efficacy of Ablative Fractional 2940 nm Laser Treatment for Lichen Sclerosus Lesion","Inclusion Criteria:\n\n* Female aged 18 years or older\n* Biopsy-proven vulvar lichen sclerosus lesion\n* Experiencing one or more of the following symptoms of LS:\n\n  1. Dryness\n  2. Itching\n  3. Burning\n  4. Bleeding\n  5. Blistering\n  6. Soreness\n  7. Easily bruises\n  8. Easily tears\n  9. Ulcerated lesions\n  10. Painful intercourse\n* Negative urine pregnancy test if subject is of childbearing potential before enrollment\n* Absence of vulvovaginal infection i.e. fungi, bacterial vaginosis, and STI\n* Ability to understand and sign informed consent, questionnaires, and all investigation requirements\n* Willing to consent to clinical photographs of the treatment area\n* Willing to consent to ultrasound images of the treatment area\n* Willing and able to logistically follow schedule of treatments and follow-up visits\n\nExclusion Criteria:\n\n* Pregnancy, less than 3 months postpartum, or planning to become pregnant during the investigation to protect integrity of the data\n* Is a nursing mother\n* History of uncontrolled malignant disease\n* Active urogenital infection or chronic infection (i.e., candida, herpes, herpes simplex, bacterial vaginosis, trichomoniasis, or other infection)\n* Immunocompromised (e.g., lymphoma, AIDS, Wiskott-Aldrich syndrome)\n* Subjects with genital skin disease, psoriasis due to risk of koeberizing\n* Subjects on immunosuppressants: mycophenolate, retinoids, azathioprine, cyclosporin\n* Known allergy or intolerance to local anesthesia\n* Known history of connective tissue disease\n* Known propensity for keloid formations\n* Known medical condition that may affect wound healing\n* Any reason that the investigator deems prohibits participation in the investigation",true,"FEMALE","18 Years",{"count":63,"type":64},50,"ESTIMATED","INTERVENTIONAL",[67],"NA","Fractional ablative laser treatment for Lichen Sclerosus lesion",[70],"Lichen Sclerosus Lesion","2026-04-21",{"date":73,"type":74},"2026-04-23","ACTUAL",{"date":76,"type":74},"2024-03-01",{"date":78,"type":64},"2027-12-30",{"name":5,"class":6},1]