[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100529590":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":37,"centralContacts":41,"locations":50,"responsibleParty":67,"collaborators":30,"id":70,"slug":71,"hasResults":72,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":30,"eligibilityCriteria":76,"healthyVolunteers":72,"sex":77,"minAge":78,"maxAge":79,"enrollmentInfo":80,"targetDuration":30,"studyType":83,"phases":84,"briefSummary":86,"conditions":87,"keywords":89,"overallStatus":53,"whyStopped":30,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":102},{"fullName":5,"class":6},"Derzhavin Tambov State University","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Laser","ACTIVE_COMPARATOR","to take photo of problem area in the patient's standing position in the room with artificial lighting using the Canon SX510 HS from a distance of 50 cm.\n\nto measure the maximum diameter of telangiectasia using the Ultrasound Mindray M7 .\n\nto treat the reticular vein by the Nd:YAG laser with a wavelength of 1064 nm, a 7 mm spot, pulse length of 50 msec and fluency 140 J\u002Fcm2",[13],"Procedure: Laser ablation",{"label":15,"type":10,"description":16,"interventionNames":17},"Laser with Sclerotherapy","to take photo of problem area in the patient's standing position in the room with artificial lighting using the Canon SX510 HS from a distance of 50 cm.\n\nto measure the maximum diameter of telangiectasia using the Ultrasound Mindray M7 .\n\nto treat the reticular vein by the Nd:YAG laser with a wavelength of 1064 nm, a 7 mm spot, pulse length of 15 msec and fluency 70 J\u002Fcm2 to inject the 0.3% foam polidocanol with a 5 ml luer-lock syringe through 30 G needle into reticular vein until the vessel disappears.",[18],"Procedure: Laser with Sclerotherapy",{"label":20,"type":10,"description":21,"interventionNames":22},"Sclerotherapy","to take photo of problem area in the patient's standing position in the room with artificial lighting using the Canon SX510 HS from a distance of 50 cm.\n\nto measure the maximum diameter of telangiectasia using the Ultrasound Mindray M7 .\n\nto inject the 0.5% foam polidocanol with a 5 ml luer-lock syringe through 30 G needle into reticular vein until the vessel disappears.",[23],"Procedure: Sclerotherapy",[25,31,34],{"type":26,"name":27,"description":28,"armGroupLabels":29,"otherNames":30},"PROCEDURE","Laser ablation","Examination, photographing, inclusion in the study, signing of informed consent, randomization, diameter measurement, laser",[9],null,{"type":26,"name":15,"description":32,"armGroupLabels":33,"otherNames":30},"Examination, photographing, inclusion in the study, signing of informed consent, randomization, diameter measurement, laser plus sclerotherapy",[15],{"type":26,"name":20,"description":35,"armGroupLabels":36,"otherNames":30},"Examination, photographing, inclusion in the study, signing of informed consent, randomization, diameter measurement, sclerotherapy",[20],[38],{"name":39,"affiliation":5,"role":40},"Oksana V Bukina, PhD","PRINCIPAL_INVESTIGATOR",[42,46],{"name":39,"role":43,"phone":44,"phoneExt":30,"email":45},"CONTACT","+79051204983","ovsafonova@yandex.ru",{"name":47,"role":43,"phone":48,"phoneExt":30,"email":49},"Gusen I Kurbanov","+79622348861","alpha297@mail.ru",[51],{"facility":52,"status":53,"city":54,"state":30,"zip":55,"country":56,"countryCode":57,"cosmosGeoPoint":58,"geoPoint":63,"contacts":64},"Bukina Oksana Vasilyevna","RECRUITING","Tambov","392002","Russia","RU",{"type":59,"coordinates":60},"Point",[61,62],41.44102,52.73632,{"lat":62,"lon":61},[65,66],{"name":39,"role":43,"phone":44,"phoneExt":30,"email":45},{"name":47,"role":43,"phone":48,"phoneExt":30,"email":49},{"type":40,"investigatorFullName":68,"investigatorTitle":69,"investigatorAffiliation":5,"oldNameTitle":30,"oldOrganization":30},"Oksana Bukina","Director, Clinical Research","100529590","laser-treatment-of-reticular-leg-veins-vs-sclerotherapy-100529590",false,"NCT06175754","Laser Treatment of Reticular Leg Veins vs. Sclerotherapy","Treatment of Reticular Leg Veins: a Prospective, Randomized, Comparative Clinical Trial of a 1064 nm Nd:YAG Long Pulse Laser, Combined Treatment of a 1064 nm Nd:YAG Long Pulse Laser and Sclerotherapy vs. Sclerotherapy Alone.","Inclusion Criteria:\n\n* women over 18\n* reticular veins\n* signed informed consent to participate in the study\n\nExclusion Criteria:\n\n* diabetes mellitus\n* pregnancy or lactation\n* malignant neoplasms\n* inability or unwillingness of the patient to wear compression stockings\n* hypersensitivity to the polidocanol, cold, sunlight\n* concomitant diseases: bronchial asthma, severe liver and kidney disease, acute thrombosis and thrombophlebitis, infection of the skin and\u002For soft tissues, infectious diseases, arteriosclerosis, diabetic angiopathy, heart defects requiring surgery, fever, toxic hyperthyroidism, obesity, tuberculosis, sepsis, violation of the cellular composition of the blood, all diseases requiring bed rest, heart disease with decompensation phenomena,\n* known hereditary thrombophilia.\n* period after treatment of alcoholism\n* reception of oral contraceptives\n* sedentary lifestyle","FEMALE","18 Years","75 Years",{"count":81,"type":82},174,"ESTIMATED","INTERVENTIONAL",[85],"NA","Treatment of reticular veins with a 1064 nm long-pulsed Nd:YAG laser and combination of a 1064 nm Nd:YAG long pulse laser and sclerotherapy should be no less effective than sclerotherapy alone, and have a frequency of adverse events less then sclerotherapy alone.",[88],"Reticular Leg Veins",[90,91,92],"reticular veins","long-pulsed Nd:YAG laser","sclerotherapy","2025-02-03",{"date":95,"type":96},"2025-02-05","ACTUAL",{"date":98,"type":96},"2023-10-09",{"date":100,"type":82},"2025-12-09",{"name":5,"class":6},1]