[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100584993":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":28,"centralContacts":33,"locations":38,"responsibleParty":51,"collaborators":54,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":63,"eligibilityCriteria":64,"healthyVolunteers":59,"sex":65,"minAge":66,"maxAge":12,"enrollmentInfo":67,"targetDuration":12,"studyType":70,"phases":71,"briefSummary":73,"conditions":74,"keywords":76,"overallStatus":83,"whyStopped":12,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},{"fullName":5,"class":6},"Sahlgrenska University Hospital","OTHER",[8,13],{"label":9,"type":10,"description":11,"interventionNames":12},"Rectal cancer surgery without lateral lymph node dissection","NO_INTERVENTION","Rectal cancer surgery without lateral lymph node dissection. Applicable if no lateral lymph nodes on primary MRI or lateral lymph nodes ≤4 mm after neoadjuvant treatment No lateral lymph node dissection",null,{"label":14,"type":15,"description":16,"interventionNames":17},"Rectal cancer surgery with lateral lymph node dissection","EXPERIMENTAL","Rectal cancer surgery with lateral lymph node dissection. Applicable if lateral lymph nodes on primary MRI that persist after neoadjuvant treatment (\\> 4 mm) .\n\nLateral lymph node dissection",[18],"Procedure: Lateral lymph node dissection",[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","Lateral lymph node dissection","Removal of lateral lymph nodes in the obturator and internal iliac compartment including fatty tissue, but excluding vascular and nervous tissue",[14],[26,27],"Lateral lymph node clearance","Lateral lymph node removal",[29],{"name":30,"affiliation":31,"role":32},"Eva Angenete, MD PhD","Sahlgrenska Universitetssjukhuset","PRINCIPAL_INVESTIGATOR",[34],{"name":30,"role":35,"phone":36,"phoneExt":12,"email":37},"CONTACT","+46760514441","eva.angenete@vgregion.se",[39],{"facility":40,"status":12,"city":41,"state":12,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":12},"Dept. of Surgery, Sahlgrenska University Hospital\u002FOstra","Gothenburg","SE 416 85","Sweden","SE",{"type":46,"coordinates":47},"Point",[48,49],11.96679,57.70716,{"lat":49,"lon":48},{"type":32,"investigatorFullName":52,"investigatorTitle":53,"investigatorAffiliation":5,"oldNameTitle":12,"oldOrganization":12},"Eva Angenete","Professor",[55],{"name":56,"class":6},"Göteborg University","100584993","latitude---lateral-lymph-node-attitude-study-100584993",false,"NCT06896578","Latitude - Lateral Lymph Node Attitude Study","Lateral Lymph Nodes in Rectal Cancer Attitude Study","Latitude","Inclusion Criteria:\n\n* 18 years or older\n* written informed consent\n* adenocarcinoma verified tumour below ≤ 8 cm from anal verge measured by rectoscopy and\u002For MRI\n* clinical tumor (cT) stage cT3, cT4a or cT4b on MRI or\n* adenocarcinoma verified tumour at any height ≤ 15 cm from anal verge measured by rectoscopy and\u002For MRI regardless of T\u002FN stage with visible lateral lymph node (according to definition 2.4.2) on pre-therapeutic MRI or PET-CT\n\nExclusion Criteria:\n\n* Not biopsy confirmed rectal cancer (adenocarcinoma)\n* Recurrent rectal cancer\n* Age below 18\n* Participation in other trials in conflict with the protocol and end-points of the Latitude study\n* No informed consent","ALL","18 Years",{"count":68,"type":69},1000,"ESTIMATED","INTERVENTIONAL",[72],"NA","Patients with advanced rectal cancer can sometimes have suspected tumour affected lymph nodes outside the standard operating field. These patients often receive preoperative treatment before surgery. There is a lack of consensus on what to do if there is remaining suspicion of tumour affected lymph nodes after the preoperative treatment. Removal of the lymph nodes using a broader surgical field with dissection of the lateral side-wall is often suggested, but the oncologic outcome is uncertain, and so is the patient reported outcome in terms of side effects.\n\nThis study aims to study the surgical treatment of tumour affected lateral lymph nodes to understand what lymph nodes require removal, and what effect that will have on oncologic outcome and the patient's function and QoL.",[75],"Rectal Neoplasm Malignant",[77,78,79,80,81,82],"lateral lymph nodes","Quality of life","local recurrence","thrombosis","lymph oedema","lateral lymph node dissection","NOT_YET_RECRUITING","2025-08-07",{"date":86,"type":87},"2025-08-08","ACTUAL",{"date":89,"type":69},"2025-09-15",{"date":91,"type":69},"2034-02-01",{"name":5,"class":6},1]