[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100616154":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":26,"locations":31,"responsibleParty":49,"collaborators":26,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":26,"eligibilityCriteria":59,"healthyVolunteers":55,"sex":60,"minAge":61,"maxAge":62,"enrollmentInfo":63,"targetDuration":26,"studyType":66,"phases":67,"briefSummary":69,"conditions":70,"keywords":73,"overallStatus":33,"whyStopped":26,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"Cairo University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Banded Leaf expander supported on the maxillary first permanent molars","EXPERIMENTAL","9mm leaf expander delievering 900 gm force will be supported on the upper first permanent molars with the appliance arm extending to the canines",[13],"Device: The Leaf expander",{"label":15,"type":16,"description":17,"interventionNames":18},"Banded Hyrax expander supported on the maxillary first permanent molars","ACTIVE_COMPARATOR","9mm Hyrax expander will be supported on the upper first permanent molars with the appliance arm extending to the canines",[19],"Device: Hyrax expander",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","The Leaf expander","The Leaf expander incorporates Nickel Titanium springs that will not require the patients' home activation",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Hyrax expander","Hyrax expander incorporates a screw that requires the patients' home activation",[15],[32],{"facility":5,"status":33,"city":34,"state":26,"zip":26,"country":35,"countryCode":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"RECRUITING","Cairo","Egypt","EG",{"type":38,"coordinates":39},"Point",[40,41],31.24967,30.06263,{"lat":41,"lon":40},[44],{"name":45,"role":46,"phone":47,"phoneExt":26,"email":48},"Noura Saleh, Masters in Orthodontics","CONTACT","122476422","noura.mohamed@dentistry.cu.edu.eg",{"type":50,"investigatorFullName":51,"investigatorTitle":52,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Noura Mohamed Hamza Hassan Saleh","Principal investigator","100616154","leaf-expander-versus-hyrax-expander-in-mixed-dentition-patients-with-posterior-crossbite-100616154",false,"NCT07301918","Leaf Expander Versus Hyrax Expander in Mixed Dentition Patients With Posterior Crossbite.","Evaluation of the Effects of the Leaf Expander Versus Hyrax Expander in Mixed Dentition Patients With Posterior Crossbite: A Randomized Clinical Trial.","Inclusion Criteria:\n\n* Male and female patients\n* Mixed dentition stage\n* Unilateral or bilateral posterior crossbite.\n* Patients in prepubertal stage with cervical vertebral maturation stage 1-3.\n* Fully erupted maxillary and mandibular permanent first molars.\n* Skeletal class I or II.\n\nExclusion Criteria:\n\n* Previous orthodontic treatment.\n* Missing teeth.\n* Inadequate oral hygiene.\n* Patients with bad oral habits.\n* Patients with medical conditions.\n* Patients with cleft lip and palate.","ALL","6 Years","12 Years",{"count":64,"type":65},30,"ESTIMATED","INTERVENTIONAL",[68],"NA","Design: Two-arm parallel randomized clinical trial in mixed dentition (6-12 years).\n\nArms: (1) 9 mm, 900 g leaf expander; (2) 9 mm Hyrax expander. Follow-up: From appliance insertion → completion of intended expansion → 6-month retention.\n\nPrimary outcome: Pain perception during the first 7 days post-insertion (daily patient-reported scale).\n\nSecondary outcomes: Skeletal and dental changes on CBCT.",[71,72],"Posterior Crossbite","Maxilla; Hypoplasia",[74,75,76,77],"expander","maxillary transverse deficiency","posterior crossbite","mixed dentition","2026-06-03",{"date":80,"type":81},"2026-06-04","ACTUAL",{"date":83,"type":81},"2025-10-01",{"date":85,"type":65},"2027-03",{"name":5,"class":6},1]