[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100543161":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":10,"centralContacts":23,"locations":32,"responsibleParty":48,"collaborators":10,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":10,"eligibilityCriteria":58,"healthyVolunteers":54,"sex":59,"minAge":10,"maxAge":10,"enrollmentInfo":60,"targetDuration":10,"studyType":63,"phases":10,"briefSummary":64,"conditions":65,"keywords":10,"overallStatus":69,"whyStopped":10,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":79},{"fullName":5,"class":6},"All India Institute of Medical Sciences","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Lesioning group",null,"Participants who undergo pallidal, subthalamic or thalamic lesioning for the management of Dystonia, Parkinson's disease or essential tremors",[13],"Procedure: Pallidal, subthalamic or thalamic lesioning",{"label":15,"type":10,"description":16,"interventionNames":10},"Control group","Participants who were considered for pallidal, subthalamic or thalamic lesioning for the management of Dystonia, Parkinson's disease or essential tremors but went on to continue best medical management",[18],{"type":19,"name":20,"description":21,"armGroupLabels":22,"otherNames":10},"PROCEDURE","Pallidal, subthalamic or thalamic lesioning","Radiofrequency, ultrasound guided or other lesioning procedures of the Globus pallidus interna, subthalamic nucleus or Vim nucleus of the thalamus for the management of Movement disorders",[9],[24,29],{"name":25,"role":26,"phone":27,"phoneExt":10,"email":28},"Arunmozhimaran Elavarasi, MD DM","CONTACT","+919013844274","arun_ela@yahoo.com",{"name":30,"role":26,"phone":10,"phoneExt":10,"email":31},"Manjari Tripathi, DM","mtripathiaiims@gmail.com",[33],{"facility":34,"status":10,"city":35,"state":36,"zip":37,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"All India Institute of Medical Sciences, New Delhi","New Delhi","National Capital Territory of Delhi","110029","India","IN",{"type":41,"coordinates":42},"Point",[43,44],77.2148,28.62137,{"lat":44,"lon":43},[47],{"name":25,"role":26,"phone":27,"phoneExt":10,"email":28},{"type":49,"investigatorFullName":50,"investigatorTitle":51,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Arunmozhimaran Elavarasi","Assistant Professor","100543161","lesioning-procedures-for-movement-disorders-100543161",false,"NCT06352268","Lesioning Procedures for Movement Disorders","Clinical, Laboratory and Imaging Features, Treatment Trends and Long Term Outcomes of Patients Undergoing Lesioning Procedures for Movement Disorders - A Cohort Study and Registry","Inclusion Criteria:\n\n* Patients with movement disorders admitted at the Neurology wards\u002Fattending clinics\n* Who are being considered for lesioning procedures\n* Of all ages and sexes\n\nExclusion Criteria:\n\n· Those who deny consent","ALL",{"count":61,"type":62},250,"ESTIMATED","OBSERVATIONAL","Dystonia is a rare syndrome with varying etiologies. Similarly, tremor conditions refractory to medical management and disabling that they need surgical interventions are rare in our setting. So far there are no randomized controlled trials of pallidotomy for management of dystonia. There is scant literature on the long term efficacy and safety of Pallidotomy, thalamotomy and other such lesioning procedures in the management of movement disorders. The current literature is significantly plagued by publication bias as case reports with successful outcomes are likely to be selectively published in journals or conference abstracts. Lesioning procedures though seem to be effective are often considered to be risky, especially bilateral pallidotomy is not preferred by several centres. However, our center routinely performs simultaneous bilateral pallidotomy. To generate long term data on the efficacy and safety of lesioning procedures in rare diseases like dystonias especially the effect of functional neurosurgery on varying etiologies of the disease, robust registries are required which collect data on all consecutive patients who undergo the procedure.",[66,67,68],"Dystonia","Parkinson Disease","Essential Tremor","NOT_YET_RECRUITING","2024-04-04",{"date":72,"type":73},"2024-04-08","ACTUAL",{"date":75,"type":62},"2024-04-15",{"date":77,"type":62},"2028-12-31",{"name":5,"class":6},1]